Product image of Librofem (Ibuprofen Bp) supplied by GNH India

Librofem

Active Ingredient:
Ibuprofen Bp
Origin:
EU

Librofem (Ibuprofen Bp)

Ibuprofen, the active ingredient in Librofem, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It is used to relieve mild to moderate pain, reduce fever, and treat inflammatory conditions in adults and children when appropriate.
GNH India supplies Librofem as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Activase Pharmaceuticals Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Librofem (ibuprofen) acts on the cyclooxygenase pathway to manage pain, fever and inflammation.

  • Pain: provides relief of mild to moderate acute pain such as headache, dental or musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammatory conditions: reduces swelling and discomfort in disorders like osteoarthritis, rheumatoid arthritis and dysmenorrhea.

How It Works

  • Ibuprofen reversibly inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis diminishes inflammation, lowers pain‑signal sensitisation, and resets the hypothalamic set‑point for body temperature, producing analgesic, antipyretic and anti‑inflammatory effects.

Side Effects

Adverse reactions may range from mild to serious, depending on individual susceptibility and duration of therapy.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or heartburn.
  • Headache or dizziness.
  • Mild rash or itching.
  • Elevated blood pressure in susceptible patients.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome.
  • Renal impairment or acute kidney injury.
  • Hepatotoxicity with elevated liver enzymes.
  • Cardiovascular events including myocardial infarction or stroke.
  • Hematologic abnormalities like thrombocytopenia.

Precautions & Warnings

Before initiating Librofem, consider the following safety measures:

  • Assess gastrointestinal risk: avoid use in patients with active ulcers or a history of GI bleeding.
  • Evaluate renal function: monitor creatinine in patients with chronic kidney disease.
  • Monitor cardiovascular status: use the lowest effective dose in those with heart disease.
  • Avoid in known hypersensitivity to ibuprofen or other NSAIDs.
  • Use concomitant anticoagulants with caution and under medical supervision.
  • Store at ambient temperature: keep in the original container, protect from moisture and excessive heat.

Avoid Interactions

Ibuprofen can affect the pharmacokinetics or pharmacodynamics of several medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Corticosteroids: synergistic ulcerogenic effect.
  • Lithium: elevated lithium serum concentrations.
  • Methotrexate: reduced renal clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function.
  • Diuretics: risk of reduced renal perfusion.
  • Selective serotonin reuptake inhibitors (SSRIs): additive bleeding risk.
  • Antihypertensive agents: may blunt blood pressure control.
  • Beta‑blockers: monitor for potential changes in heart rate.

Frequently Asked Questions

Librofem contains ibuprofen, which is indicated for the relief of mild to moderate pain such as headaches, dental pain, or musculoskeletal aches, for the reduction of fever, and for the management of inflammatory conditions including arthritis and dysmenorrhea. It works across a broad range of acute and chronic inflammatory disorders.

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, ibuprofen reduces inflammation, diminishes pain‑signal transmission, and resets the hypothalamic thermostat that controls body temperature.

The appropriate dose of Librofem is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and response to therapy. Healthcare professionals consider the lowest effective dose for the shortest duration needed to achieve therapeutic goals.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because of potential fetal complications, and caution is advised during the first two trimesters. Breastfeeding mothers should consult their physician, as small amounts may be excreted in milk.

To place an order, submit an enquiry on the Librofem product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both ibuprofen (Librofem) and naproxen belong to the NSAID class and share similar mechanisms of COX inhibition. Ibuprofen generally has a shorter half‑life, which may require more frequent dosing, while naproxen offers a longer duration of action. Choice between them depends on patient‑specific factors, tolerability, and physician preference.

Librofem should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keeping the tablets in a dry, cool place helps maintain potency and prevents degradation.

Librofem is taken orally, usually with a full glass of water. It may be taken with or without food, although taking it with food can reduce the likelihood of stomach upset. Patients should follow the dosing schedule prescribed by their healthcare provider.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, hepatotoxicity, and an increased chance of cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they notice signs of these conditions.

Librofem should not be used by individuals with a known hypersensitivity to ibuprofen or any NSAID, those with active gastrointestinal bleeding or ulcer disease, patients with severe renal or hepatic impairment, and anyone in the third trimester of pregnancy. Consultation with a healthcare professional is essential before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.