Licain (Lidocaine Hydrochloride)

Lidocaine works by reversibly binding to voltage‑gated sodium channels on neuronal membranes, stabilizing them in an inactive state. This prevents the influx of sodium ions required for depolarization, thereby halting the propagation of nerve impulses and producing a localized loss of sensation.

The appropriate dose of Licain is determined by the prescribing clinician based on the specific procedure, patient characteristics, and route of administration. Healthcare professionals calculate the amount required to achieve effective anesthesia while maintaining safety.

Safety data for lidocaine hydrochloride in pregnancy and lactation are limited. It should be used only when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.

To order Licain, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials. The team then provides pricing, availability, shipping details (including cold‑chain if needed) and assists with import documentation.

Lidocaine is an amide‑type local anesthetic with a rapid onset and moderate duration, making it suitable for many procedures. Compared with bupivacaine, lidocaine has a shorter duration but a lower risk of cardiotoxicity, while it offers faster onset than procaine, an ester‑type anesthetic.

Licain should be stored below 25 °C in its original packaging, protected from moisture and light. Ensure the container is sealed tightly and avoid exposure to extreme temperatures. Follow standard aseptic techniques when preparing for injection.

Licain is supplied as a sterile solution for injection and can be given epidurally, intramuscularly, or intravenously. Administration is performed by qualified healthcare professionals who calculate the appropriate volume based on the clinical indication and monitor the patient for efficacy and safety.

Serious risks include cardiac arrhythmias, seizures, severe allergic reactions (anaphylaxis), and methemoglobinemia. These events are rare but require immediate medical attention. Monitoring of cardiovascular and neurologic status during and after administration helps mitigate these risks.

Licain should not be used in patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, in individuals with severe heart block or uncontrolled arrhythmias, and in patients with significant hepatic impairment without dose adjustment. Contraindications are determined by the prescribing clinician.