Product image of Licoforte (Hydroquinone) supplied by GNH India

Licoforte

Active Ingredient:
Hydroquinone
Origin:
EU

Licoforte (Hydroquinone)

Hydroquinone, the active ingredient in Licoforte, is a depigmenting agent presented as a topical formulation for skin application. It reduces excess melanin production and is employed to treat hyperpigmentation disorders such as melasma, age spots, and other dark patches in adults. It is indicated for use on facial and body skin where discoloration is present, and is formulated for safe topical use under medical supervision.

GNH India supplies Licoforte as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution.

Manufacturer / TM Owner

Industrial Farmaceutica Cantabria, S.A.

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Indications & Clinical Uses

  • Licoforte (hydroquinone) is used to manage disorders of melanin overproduction affecting the skin.
  • Hyperpigmentation: lightens dark patches by inhibiting melanin synthesis, resulting in a more uniform skin colour.
  • Melasma: diminishes facial discoloration and evens skin tone through gradual pigment reduction.
  • Age spots: fades solar lentigines and improves the appearance of sun‑induced spots by decreasing melanin content.

How It Works

  • Hydroquinone acts as a reversible inhibitor of the enzyme tyrosinase, which catalyzes the oxidation of tyrosine to DOPA and subsequently to melanin within melanocytes. By blocking this key step, hydroquinone reduces the production of melanin pigments, leading to gradual lightening of hyperpigmented skin areas when applied topically over a period of weeks.

Side Effects

Topical hydroquinone may cause a range of local skin reactions, varying from mild to severe.

Common Side Effects

  • Skin irritation or redness at the application site.
  • Dryness or flaking of the treated skin.
  • Mild itching or tingling sensation.
  • Slight burning or warmth during initial use.
  • Peeling or scaling of the epidermis.

Serious or Rare Side Effects

  • Exogenous ochronosis (paradoxical darkening of the skin).
  • Allergic contact dermatitis with swelling or vesicles.
  • Severe erythema or ulceration.
  • Bullous reactions or extensive blistering.
  • Persistent hyperpigmentation after discontinuation.

Precautions & Warnings

  • When using Licoforte, several safety measures should be observed to minimize adverse reactions and ensure effective treatment.
  • Sun exposure: limit direct sunlight and apply broad‑spectrum sunscreen daily.
  • Application area: avoid applying to broken, inflamed or infected skin.
  • Duration of use: follow the prescriber's recommended treatment period and discontinue if irritation persists.
  • Combination therapy: do not use concurrently with other topical bleaching agents without medical advice.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Hydroquinone can interact with certain topical agents, affecting safety or efficacy.

Major Interactions (Avoid)

  • Other depigmenting agents (e.g., phenol, mercury compounds): increased risk of severe irritation.
  • Strong photosensitizers (e.g., psoralen): heightened sun sensitivity.
  • Potent corticosteroids: may mask early signs of irritation.

Moderate Interactions (Monitor Closely)

  • Retinoids (e.g., tretinoin): may enhance depigmenting effect but also increase irritation.
  • Alpha‑hydroxy acids: can amplify skin dryness and sensitivity.
  • Antioxidant creams: generally safe but monitor for unexpected skin reactions.

Frequently Asked Questions

Licoforte contains hydroquinone and is indicated for the topical treatment of skin hyperpigmentation conditions such as melasma, age spots and other dark patches. It works by lightening the affected areas when applied under medical supervision.

Hydroquinone reduces skin colour by inhibiting the enzyme tyrosinase, which is essential for melanin production in melanocytes. Blocking this pathway lowers melanin synthesis, leading to a gradual fading of pigmented lesions with regular topical application.

The dosage regimen for Licoforte is determined by the prescribing healthcare professional based on the severity of the pigmentation, the area to be treated and individual skin tolerance. Patients should follow the specific instructions provided on the prescription label.

Safety of hydroquinone during pregnancy or lactation has not been established. It should only be used if the prescriber judges that the potential benefit outweighs any possible risk to the fetus or infant.

Enquiries for Licoforte can be submitted on the product page at gnhindia.com, where you specify the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import paperwork.

Hydroquinone is considered the gold‑standard depigmenting agent because it directly inhibits tyrosinase. Alternatives such as azelaic acid, kojic acid or tretinoin may be less potent or act through different mechanisms, and they often require combination therapy to achieve comparable results.

Licoforte should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from light and moisture, and avoid freezing. Do not use the product after the expiry date.

Apply a thin layer of Licoforte to clean, dry skin once or twice daily as directed by the prescriber. Avoid the eyes, mucous membranes and broken skin. Wash hands after application and use sunscreen on treated areas during daylight.

Serious adverse events include exogenous ochronosis (paradoxical darkening), severe allergic contact dermatitis, extensive blistering or ulceration, and persistent hyperpigmentation after discontinuation. Any of these signs require immediate medical evaluation.

Licoforte should be avoided by individuals with known hypersensitivity to hydroquinone, those with broken or inflamed skin in the treatment area, children, pregnant or breastfeeding women, and patients using other strong bleaching agents without professional guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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