Product image of Lidbree (Lidocaine) supplied by GNH India

Lidbree

Active Ingredient:
Lidocaine
Origin:
EU

Lidbree (Lidocaine)

Lidocaine, the active ingredient in Lidbree, is a local anesthetic presented as a solution for intrauterine use. It provides a numbing effect for gynecologic procedures and is used in adult patients undergoing intrauterine interventions.

GNH India supplies Lidbree as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Gedeon Richter Plc.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lidbree (lidocaine) is employed in gynecologic procedures that require local anesthesia of the uterine cavity.

  • Hysteroscopic surgery: provides analgesia to reduce patient discomfort during operative hysteroscopy.
  • IUD insertion: numbs the endocervical canal to facilitate smooth device placement.
  • Endometrial biopsy: minimizes pain associated with tissue sampling from the uterine lining.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels in neuronal membranes, preventing the initiation and propagation of nerve impulses. By stabilising the neuronal membrane, it inhibits the transmission of pain signals from the uterine tissue, producing a rapid and reversible loss of sensation at the site of application.

Side Effects

Lidbree may cause a range of adverse reactions, most of which are mild and transient, while rare events can be serious.

Common Side Effects

  • Burning sensation at application site
  • Mild uterine cramping
  • Nausea
  • Dizziness
  • Headache
  • Local irritation

Serious or Rare Side Effects

  • Allergic reaction (rash, angioedema, anaphylaxis)
  • Cardiovascular toxicity (arrhythmia, hypotension)
  • Seizures
  • Methemoglobinemia
  • Severe hypotension
  • Respiratory depression

Precautions & Warnings

When using Lidbree, several safety measures should be observed to minimise risk.

  • Allergy assessment: confirm no known hypersensitivity to lidocaine or amide‑type anesthetics.
  • Cardiac monitoring: observe heart rhythm and blood pressure during administration.
  • Dose limitation: use the lowest effective amount for the procedure.
  • Avoid intravascular injection: aspirate before injection to prevent systemic exposure.
  • Caution in hepatic impairment: reduce dose as lidocaine is metabolised by the liver.
  • Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Lidbree can interact with other medicines, altering its safety profile.

Major Interactions (Avoid)

  • Amiodarone: may increase lidocaine plasma levels leading to toxicity.
  • Cimetidine: inhibits metabolism and raises systemic exposure.
  • Erythromycin: can reduce clearance and enhance adverse effects.
  • Class I antiarrhythmics (e.g., quinidine): additive cardiac conduction effects.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may potentiate bradycardia.
  • Calcium channel blockers: can enhance cardiac depressant effects.
  • Other local anesthetics: risk of cumulative toxicity.
  • MAO inhibitors: may increase risk of hypertensive reactions.

Frequently Asked Questions

Lidbree is a lidocaine‑based solution designed for intrauterine administration. It is used to provide local anesthesia during gynecologic procedures such as hysteroscopic surgery, intrauterine device (IUD) placement, and endometrial biopsy, helping to reduce pain and improve patient comfort.

Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, which stops the initiation and propagation of nerve impulses. By stabilising the neuronal membrane, it prevents the transmission of pain signals from the uterine tissue, resulting in a rapid and reversible loss of sensation at the site of application.

The specific dose of Lidbree is determined by the prescribing clinician based on the type of procedure, patient characteristics, and clinical guidelines. Healthcare professionals calculate the appropriate volume and concentration to achieve effective anesthesia while minimising systemic exposure.

Safety data for intrauterine lidocaine during pregnancy and lactation are limited. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified obstetrician after careful assessment.

To order Lidbree, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any required import documentation.

Lidbree (lidocaine) offers a rapid onset and moderate duration of action, which is comparable to other amide‑type local anesthetics such as bupivacaine. Lidocaine generally has a lower risk of prolonged cardiac toxicity, but its duration may be shorter, making it suitable for brief procedures.

Lidbree should be stored at room temperature, below 25 °C, in its original container. Protect the solution from moisture, direct sunlight and extreme temperatures. Ensure the vial is sealed until use and discard any product that appears discoloured or contaminated.

Lidbree is administered directly into the uterine cavity by a qualified healthcare professional. The solution is typically injected through a catheter or syringe under aseptic conditions, with careful aspiration to avoid intravascular injection before delivering the anesthetic.

Serious risks include allergic reactions such as anaphylaxis, cardiovascular toxicity (arrhythmias, severe hypotension), seizures, methemoglobinemia, and respiratory depression. Immediate medical attention is required if any of these symptoms develop during or after administration.

Lidbree should be avoided in patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, those with severe hepatic impairment, and individuals with significant cardiac conduction disorders unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.