Product image of Lidet (Naproxen) supplied by GNH India

Lidet

Active Ingredient:
Naproxen
Origin:
EU

Lidet (Naproxen)

Naproxen, the active ingredient in Lidet, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It is employed to relieve mild to moderate pain, reduce inflammation in musculoskeletal conditions, and lower fever in adult patients.

GNH India supplies Lidet as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality, regulatory compliance, and reliable logistics for global healthcare providers.

Manufacturer / TM Owner

Aristo Pharma Iberia, S.L.

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Indications & Clinical Uses

  • Naproxen acts systemically to alleviate pain and inflammation associated with several common conditions.
  • Mild to moderate pain: provides analgesic relief by decreasing pain perception.
  • Osteoarthritis: reduces joint inflammation and improves mobility.
  • Rheumatoid arthritis: helps control inflammatory activity and joint swelling.
  • Fever: lowers elevated body temperature through antipyretic action.

How It Works

  • Naproxen non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis diminishes inflammatory mediators, leading to reduced pain, swelling, and fever at the site of tissue injury.

Side Effects

Naproxen may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Dyspepsia or upset stomach.
  • Nausea or vomiting.
  • Headache.
  • Dizziness.
  • Mild abdominal discomfort.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment.
  • Cardiovascular events such as myocardial infarction.
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome).
  • Hepatic dysfunction.
  • Anaphylactic reactions.

Precautions & Warnings

  • Before initiating therapy, consider patient‑specific factors and monitor for adverse events.
  • Assess renal function: avoid or adjust use in patients with significant renal impairment.
  • Evaluate cardiovascular risk: use cautiously in individuals with a history of heart disease.
  • Screen for gastrointestinal ulcer history: consider gastro‑protective measures if needed.
  • Avoid concurrent use with other NSAIDs or anticoagulants unless medically justified.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Naproxen can interact with several drug classes, influencing safety and efficacy.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened gastrointestinal bleeding.
  • ACE inhibitors or diuretics: potential reduction in renal function.

Moderate Interactions (Monitor Closely)

  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Lithium: naproxen may raise lithium serum levels.
  • Methotrexate: possible decreased clearance leading to toxicity.

Frequently Asked Questions

Lidet contains naproxen, an NSAID that is commonly prescribed to treat mild to moderate pain, reduce inflammation in osteoarthritis and rheumatoid arthritis, and lower fever. It works across a broad range of inflammatory and painful conditions in adult patients.

Naproxen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, the drug diminishes the inflammatory response, reduces swelling, and lessens the sensation of pain.

The specific dosage of Lidet is determined by the prescribing healthcare professional based on the individual’s condition, age, weight, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Naproxen is generally classified as a pregnancy‑category drug that should be avoided, especially in the third trimester, due to potential risks to the fetus. It is also excreted in breast milk, so breastfeeding mothers should consult their physician before using naproxen.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Both naproxen and ibuprofen belong to the NSAID class and share similar mechanisms of COX inhibition. Naproxen has a longer half‑life, allowing less frequent dosing, whereas ibuprofen often requires multiple daily doses. Safety profiles are comparable, but individual patient factors may favor one over the other.

Lidet should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, and store them away from direct sunlight to maintain potency.

Lidet is taken orally with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort. The tablet should be swallowed whole and not chewed or crushed.

Serious risks include gastrointestinal bleeding or ulcer perforation, cardiovascular events such as heart attack or stroke, acute kidney injury, severe skin reactions, and hepatic dysfunction. Patients should seek immediate medical attention if they experience symptoms like black stools, chest pain, sudden swelling, or rash.

Naproxen is contraindicated in individuals with known hypersensitivity to NSAIDs, active gastrointestinal ulcer disease, severe heart failure, or significant renal impairment. It should also be avoided by patients on certain anticoagulants or those with a history of serious cardiovascular events unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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