Product image of Lidocain Accord (Lidocaine Hydrochloride) supplied by GNH India

Lidocain Accord

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocain Accord (Lidocaine Hydrochloride)

Lidocaine Hydrochloride, the active ingredient in Lidocain Accord, is a local anesthetic presented as a sterile injectable solution for epidural, intramuscular and intravenous use. It provides reversible nerve block to facilitate minor surgical procedures, epidural analgesia and intravenous regional anesthesia in adult patients. The formulation is intended for use under the supervision of qualified healthcare professionals.

GNH India supplies Lidocain Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, clinics and surgical centres worldwide. The company adheres to EU quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

Accord Healthcare B.V.

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Indications & Clinical Uses

Lidocain Accord, a local anesthetic, is used to achieve temporary loss of sensation in specific clinical settings.

  • Minor surgical procedures: provides local anesthesia to facilitate incision and manipulation without pain.
  • Epidural analgesia: produces segmental nerve block for pain relief during labor or postoperative period.
  • Intravenous regional anesthesia (Bier block): induces reversible anesthesia of a limb for short surgical interventions.

How It Works

  • Lidocaine Hydrochloride blocks voltage‑gated sodium channels in neuronal membranes, stabilizing the inactive state of the channel and preventing depolarization. By inhibiting the rapid influx of sodium ions, it stops the initiation and propagation of action potentials, resulting in reversible loss of sensory and motor nerve conduction in the area where it is administered. The effect is concentration‑dependent and reversible as the drug is cleared from the tissue.

Side Effects

Adverse reactions to Lidocain Accord may vary from mild, transient events to rare serious complications.

Common Side Effects

  • Transient tingling or numbness at the injection site.
  • Mild dizziness or light‑headedness.
  • Nausea.
  • Metallic taste.

Serious or Rare Side Effects

  • Cardiac arrhythmias or conduction block.
  • Seizures due to central nervous system toxicity.
  • Severe allergic reactions such as anaphylaxis.

Precautions & Warnings

When using Lidocain Accord, consider the following precautions to ensure patient safety.

  • Dose adjustment: reduce doses in patients with hepatic impairment.
  • Monitoring: observe cardiovascular and CNS status during high‑dose or rapid administration.
  • Allergy: avoid in individuals with known hypersensitivity to amide‑type local anesthetics.
  • Pregnancy: use only if the benefit outweighs the risk, as safety data are limited.
  • Drug interactions: review concomitant use of class I antiarrhythmics and CNS depressants.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and light, retain in the original container.

Avoid Interactions

Lidocain Accord may interact with other medicines; awareness of major and moderate interactions helps mitigate risk.

Major Interactions (Avoid)

  • Class I antiarrhythmic agents (e.g., quinidine, procainamide): may increase risk of cardiotoxicity.
  • CNS depressants (e.g., benzodiazepines, opioids): may potentiate central toxicity.
  • Beta‑blockers: can enhance bradycardia when combined with high doses.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase bleeding risk with regional techniques.
  • Diuretics: may alter plasma protein binding, affecting lidocaine levels.
  • Magnesium sulfate: can potentiate neuromuscular blockade.

Frequently Asked Questions

Lidocain Accord is a sterile injectable formulation of lidocaine hydrochloride used to provide local anesthesia for minor surgical procedures, to deliver epidural analgesia for labor or postoperative pain, and to perform intravenous regional (Bier) blocks for short‑duration limb surgeries.

Lidocaine hydrochloride blocks voltage‑gated sodium channels on neuronal membranes, stabilizing them in an inactive state. This prevents the rapid influx of sodium ions required for depolarisation, thereby halting the generation and propagation of nerve impulses and producing a reversible loss of sensation in the targeted area.

The appropriate dose of Lidocain Accord is determined by the prescribing clinician based on the specific procedure, route of administration, patient weight, and clinical condition. Dosage regimens are individualized and should follow local guidelines and the prescriber’s judgment.

Safety data for lidocaine hydrochloride in pregnancy and lactation are limited. It should be used only when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To order Lidocain Accord, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Lidocain Accord offers a rapid onset and moderate duration of action, making it suitable for short‑ to medium‑length procedures. Compared with longer‑acting agents such as bupivacaine, lidocaine provides quicker recovery of motor function but may require repeat dosing for prolonged analgesia. Its safety profile is well‑established for the indicated routes.

Lidocain Accord should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. The container should remain sealed until use, and any unused portion should be discarded according to local regulations.

Lidocain Accord is administered by a qualified healthcare professional via epidural, intramuscular or intravenous injection, depending on the clinical indication. The solution is injected directly into the target tissue or vascular compartment using aseptic technique and appropriate dosing equipment.

The most serious risks include cardiovascular toxicity such as arrhythmias or cardiac arrest, central nervous system toxicity leading to seizures or loss of consciousness, and severe allergic reactions including anaphylaxis. Immediate medical attention is required if any of these events occur.

Lidocain Accord should be avoided in patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, in individuals with severe heart block or uncontrolled arrhythmias, and in patients where the risk of systemic toxicity cannot be adequately monitored.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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