Product image of Lidocain Accord (Lidocaine Hydrochloride) supplied by GNH India

Lidocain Accord

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocain Accord (Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Lidocain Accord, is a local anesthetic presented as a sterile solution for epidural, intramuscular and intravenous use. It provides reversible loss of sensation for procedures that require regional or procedural analgesia in patients of various ages.
GNH India supplies Lidocain Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Accord Healthcare B.V.

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Indications & Clinical Uses

Lidocain Accord is a local anesthetic that acts on peripheral nerves to block pain transmission.

  • Local anesthesia: provides reversible loss of sensation for minor surgical or diagnostic procedures.
  • Pain management: offers analgesia for acute postoperative or procedural pain.
  • Regional anesthesia: enables nerve block techniques such as epidural or spinal anesthesia.

How It Works

  • Lidocaine reversibly blocks voltage‑gated sodium channels in neuronal membranes, preventing the initiation and propagation of action potentials. By stabilising the neuronal membrane, it inhibits nerve impulse transmission, resulting in loss of sensation and analgesia in the targeted area.

Side Effects

Adverse reactions may occur following administration of Lidocain Accord.

Common Side Effects

  • Injection site pain: mild discomfort at the site of administration.
  • Redness or swelling: localized erythema around the injection area.
  • Transient numbness: temporary loss of sensation extending beyond the intended region.
  • Nausea: mild gastrointestinal upset.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, or anaphylaxis.
  • Cardiac arrhythmia: irregular heart rhythm that may be life‑threatening.
  • Seizure: central nervous system excitation leading to convulsions.
  • Methemoglobinemia: reduced oxygen‑carrying capacity of blood.

Precautions & Warnings

Before using Lidocain Accord, consider the following precautions.

  • Cardiac history: assess for pre‑existing heart disease or conduction abnormalities.
  • Blood pressure: monitor for hypotension, especially with large doses.
  • Allergy: avoid in patients with known lidocaine hypersensitivity.
  • Hepatic function: use caution in severe liver impairment as metabolism may be reduced.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lidocain Accord can interact with other medicines; review the following.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may increase cardiotoxicity.
  • Cimetidine: can raise plasma lidocaine levels.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers (e.g., propranolol): may enhance hypotensive effects.
  • Calcium channel blockers (e.g., verapamil): may increase risk of cardiac depression.
  • CYP3A4 inhibitors (e.g., erythromycin): may modestly raise lidocaine concentrations.

Frequently Asked Questions

Lidocain Accord is a sterile lidocaine solution used to provide local, regional or procedural anesthesia. It is commonly employed for epidural, intramuscular or intravenous administration to achieve reversible loss of sensation during minor surgeries, diagnostic procedures, or for acute pain control.

Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the influx of sodium ions that initiates action potentials. This stabilises the nerve membrane, halting the transmission of pain signals and producing a temporary loss of sensation in the treated area.

The appropriate dose of Lidocain Accord is determined by the prescribing clinician based on the specific procedure, patient weight, age, and clinical condition. Healthcare professionals calculate the dose to achieve effective anesthesia while maintaining safety.

Safety data for lidocaine during pregnancy and lactation are limited. Use is generally reserved for situations where the benefit to the mother outweighs potential risks to the fetus or infant. Clinicians should evaluate each case individually and follow local guidelines.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

The primary alternative to lidocaine is bupivacaine, another long‑acting local anesthetic. Lidocaine has a faster onset but a shorter duration of action, making it suitable for shorter procedures. Bupivacaine provides prolonged analgesia but carries a higher risk of cardiotoxicity at comparable doses.

Lidocain Accord should be stored at room temperature, below 25 °C, in its original sealed container. Protect the solution from moisture, direct sunlight and extreme temperatures. Do not freeze; discard any product that appears cloudy or contains particles.

The product is administered by a qualified healthcare professional via epidural, intramuscular or intravenous injection. The route, volume and rate are selected according to the clinical indication, patient condition and procedural requirements, following aseptic technique.

Serious risks include allergic reactions such as anaphylaxis, cardiac arrhythmias, seizures, and methemoglobinemia. These events are rare but require immediate medical attention. Monitoring of cardiovascular and neurological status is recommended during and after administration.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid the product. It is also contraindicated in individuals with severe hepatic impairment, certain cardiac conduction disorders, or when used concurrently with drugs that markedly increase lidocaine plasma levels.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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