Product image of Lidocain/Adrenalin Aguettant (Epinephrine, Lidocaine Hydrochloride) supplied by GNH India

Lidocain/Adrenalin Aguettant

Active Ingredient:
Epinephrine, Lidocaine Hydrochloride
Origin:
EU

Lidocain/Adrenalin Aguettant (Epinephrine, Lidocaine Hydrochloride)

Lidocaine hydrochloride, the active ingredient in Lidocain/Adrenalin Aguettant, is a local anesthetic presented as a sterile injectable solution for epidural, infiltration and perineural use. It provides rapid onset numbness and, together with epinephrine, prolongs anesthesia for surgical patients.

GNH India supplies Lidocain/Adrenalin Aguettant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Laboratoire Aguettant

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Indications & Clinical Uses

Lidocain/Adrenalin Aguettant is used in the local anesthetic pathway to provide targeted pain control during procedures.

  • Surgical procedures: enables local anesthesia and reduces intra‑operative bleeding
  • Epidural analgesia: extends duration of pain relief during labor or postoperative care
  • Peripheral nerve block: lengthens the effect of nerve block for orthopedic or dental surgery

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of nerve impulses. Epinephrine stimulates alpha‑adrenergic receptors on vascular smooth muscle, causing vasoconstriction that reduces systemic absorption of lidocaine, thereby prolonging its anesthetic effect and providing hemostasis at the injection site.

Side Effects

Adverse reactions to Lidocain/Adrenalin Aguettant are generally related to the local anesthetic component or the vasoconstrictor.

Common Side Effects

  • Transient burning or stinging at the injection site
  • Mild dizziness or light‑headedness
  • Tachycardia
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Cardiac arrhythmias
  • Seizures
  • Persistent hypotension

Precautions & Warnings

When using Lidocain/Adrenalin Aguettant, clinicians should observe the following precautions.

  • Patient assessment: verify allergy to amide‑type anesthetics or epinephrine
  • Cardiovascular status: avoid in uncontrolled hypertension or severe cardiac disease
  • Dose limits: adhere to recommended maximum lidocaine dose with epinephrine
  • Concurrent medications: review for MAO inhibitors or beta‑blockers
  • Store below 25°C: keep in original container, protect from light and moisture

Avoid Interactions

Lidocain/Adrenalin Aguettant may interact with other medicines; the following interactions are recognized.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis
  • Beta‑blockers: may potentiate bradycardia with epinephrine
  • Class I antiarrhythmics: increased risk of cardiac toxicity

Moderate Interactions (Monitor Closely)

  • Diuretics: may enhance hypotensive effect
  • Tricyclic antidepressants: additive CNS toxicity
  • CYP1A2 inhibitors: may increase lidocaine plasma levels

Frequently Asked Questions

Lidocain/Adrenalin Aguettant is a combination of lidocaine and epinephrine used to provide local anesthesia and prolonged analgesia for surgical procedures, epidural analgesia, infiltration anesthesia, and peripheral nerve blocks. The epinephrine component reduces bleeding and extends the duration of lidocaine’s effect.

Lidocaine blocks voltage‑gated sodium channels on nerve membranes, preventing the generation and conduction of action potentials. This interruption stops pain signals from reaching the brain, producing a rapid and reversible loss of sensation at the injection site.

The specific dose and volume are determined by the prescribing clinician based on the type of procedure, patient weight, and maximum allowable lidocaine dose with epinephrine. Healthcare professionals calculate the appropriate amount to ensure safety and efficacy.

Safety data for this combination in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Adding epinephrine to lidocaine creates vasoconstriction, which reduces systemic absorption, prolongs the anesthetic effect, and minimizes intra‑operative bleeding. Plain lidocaine provides a shorter duration of action and does not offer the same hemostatic benefit.

Store the product below 25 °C in its original packaging, protected from light and moisture. Do not freeze. Inspect the solution for particulate matter or discoloration before use, and discard if any abnormalities are observed.

The medication is supplied as a sterile injectable solution and is administered by a qualified healthcare professional via epidural, infiltration, or perineural injection techniques, following aseptic procedures and the prescribed dosage.

Serious risks include severe allergic reactions (anaphylaxis), cardiac arrhythmias, seizures, and profound hypotension. Immediate medical attention is required if any of these events occur during or after administration.

Patients with known hypersensitivity to lidocaine, other amide‑type local anesthetics, or epinephrine, as well as those with uncontrolled hypertension, severe cardiac disease, or certain arrhythmias, should not receive this product unless a risk‑benefit assessment justifies its use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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