Product image of Lidocain Aguettant (Lidocaine Hydrochloride) supplied by GNH India

Lidocain Aguettant

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocain Aguettant (Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Lidocain Aguettant, is a local anesthetic presented as a solution for injection for infiltration, intradermal and intravenous use. It provides reversible loss of sensation for minor surgical, dental and cardiac procedures in adult patients.
GNH India supplies Lidocain Aguettant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Aguettant

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Indications & Clinical Uses

Lidocaine is a local anesthetic that blocks nerve conduction in various clinical settings.

  • Minor surgical procedures: provides rapid, reversible local anesthesia for skin and soft‑tissue surgery.
  • Dental procedures: numbs oral tissues to facilitate extractions, restorations and periodontal work.
  • Intravenous antiarrhythmic use: stabilises cardiac rhythm in selected arrhythmias under monitored conditions.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the rapid influx of sodium ions required for depolarisation. This inhibition halts the initiation and propagation of nerve impulses, resulting in loss of sensation in the targeted area while sparing motor function at therapeutic concentrations.

Side Effects

Lidocaine may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Burning or stinging at the injection site
  • Tingling or numbness extending beyond the target area
  • Dizziness or light‑headedness
  • Nausea or metallic taste in the mouth

Serious or Rare Side Effects

  • Seizures or convulsions
  • Cardiac arrhythmias, including ventricular tachycardia
  • Severe allergic reactions such as anaphylaxis
  • Methemoglobinemia leading to cyanosis
  • Respiratory depression or arrest

Precautions & Warnings

When using Lidocain Aguettant, consider the following safety measures.

  • Allergy assessment: verify no known hypersensitivity to amide‑type local anesthetics.
  • Dose minimisation: employ the lowest effective concentration for the intended procedure.
  • Cardiac monitoring: observe heart rate and rhythm, especially for intravenous use.
  • Hepatic function: exercise caution in patients with severe liver disease due to altered metabolism.
  • Neurological conditions: avoid or reduce dose in individuals with epilepsy or seizure disorders.
  • Store at below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lidocaine can interact with several medicines, altering its safety or efficacy.

Major Interactions (Avoid)

  • Quinidine: may increase plasma lidocaine levels and toxicity.
  • Beta‑blockers: combined use can enhance cardiac depressant effects.
  • Other amide‑type local anesthetics: concurrent administration raises risk of systemic toxicity.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines): may potentiate central nervous system effects.
  • Diuretics (e.g., furosemide): can reduce plasma protein binding, increasing free lidocaine.
  • Cimetidine: may inhibit hepatic metabolism, modestly raising lidocaine concentrations.

Frequently Asked Questions

Lidocain Aguettant contains lidocaine hydrochloride and is employed as a local anesthetic for infiltration, intradermal and intravenous applications. It is commonly used to provide pain relief during minor surgical procedures, dental treatments, and, under monitored conditions, as an antiarrhythmic agent in cardiac care.

Lidocaine blocks voltage‑gated sodium channels on nerve membranes, preventing the rapid influx of sodium ions needed for depolarisation. By inhibiting nerve impulse generation and propagation, it produces a reversible loss of sensation in the area where it is administered, while typically preserving motor function.

The appropriate dose of Lidocain Aguettant is determined by the prescribing clinician based on the specific procedure, patient characteristics, and route of administration. Healthcare professionals calculate the dose to achieve effective anesthesia while minimising the risk of systemic toxicity.

Safety data for lidocaine in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any potential risk to the fetus or infant. Clinicians should assess each case individually and consider alternative options when possible.

To request Lidocain Aguettant, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and any required import documentation.

Lidocaine is an amide‑type local anesthetic with a rapid onset and moderate duration, making it suitable for many short‑to‑medium procedures. Compared with ester‑type agents such as procaine, lidocaine has a lower incidence of allergic reactions and a more predictable pharmacokinetic profile, though alternatives like bupivacaine may offer longer lasting anesthesia.

Lidocain Aguettant should be stored at temperatures below 25 °C, protected from moisture, light and extreme heat. Keep the vial in its original packaging until use, and avoid freezing. Follow standard aseptic techniques when preparing for injection.

The product is supplied as an injectable solution. It can be administered by infiltration into the target tissue, intradermally for superficial anesthesia, or intravenously under controlled conditions for antiarrhythmic therapy. Administration technique and volume are determined by the treating clinician.

Serious adverse events include central nervous system toxicity such as seizures, severe cardiac effects like arrhythmias or cardiac arrest, and rare allergic reactions including anaphylaxis. Prompt recognition and supportive management are essential if these events occur.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, those with severe hepatic impairment, and individuals with certain cardiac conduction disorders should avoid using Lidocain Aguettant unless a specialist determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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