Product image of Lidocain Aguettant (Lidocaine Hydrochloride) supplied by GNH India

Lidocain Aguettant

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocain Aguettant (Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Lidocain Aguettant, is a local anesthetic presented as a sterile solution for infiltration, intradermal and intravenous use. It provides reversible nerve block for minor surgical, dental and regional anesthesia procedures.

GNH India supplies Lidocain Aguettant as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Aguettant

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Indications & Clinical Uses

  • Lidocaine is a local anesthetic used to block nerve conduction in various procedural settings.
  • Minor surgical procedures: provides local anesthesia to facilitate pain‑free incision and manipulation.
  • Dental procedures: numbs oral tissues for extractions, restorations and other dental work.
  • Infiltration anesthesia: delivers targeted anesthesia for soft‑tissue surgeries.
  • Intradermal anesthesia: used for skin testing and minor dermatologic interventions.
  • Intravenous regional anesthesia: enables a Bier block for limb surgeries.

How It Works

  • Lidocaine exerts its effect by reversibly binding to the intracellular portion of voltage‑gated sodium channels on neuronal membranes. This blocks the rapid influx of sodium ions required for depolarization, thereby inhibiting the initiation and propagation of nerve impulses and producing a temporary loss of sensation in the treated area.

Side Effects

Lidocaine may cause a range of adverse reactions, most of which are dose‑related and dependent on the route of administration.

Common Side Effects

  • Tingling or numbness at the injection site
  • Burning or stinging sensation
  • Dizziness or light‑headedness
  • Nausea or metallic taste

Serious or Rare Side Effects

  • Methemoglobinemia
  • Cardiac arrhythmias or conduction block
  • Seizures or central nervous system toxicity
  • Severe allergic reactions, including anaphylaxis
  • Hypotension or respiratory depression

Precautions & Warnings

  • When using Lidocain Aguettant, clinicians should observe several safety measures.
  • Allergy assessment: verify no known hypersensitivity to amide‑type local anesthetics.
  • Cardiovascular status: use cautiously in patients with conduction disorders or severe heart disease.
  • Dosage limits: adhere to recommended maximum doses to avoid systemic toxicity.
  • Pregnancy and lactation: evaluate risk–benefit; limited data are available.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Lidocaine can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may potentiate cardiotoxicity.
  • Beta‑blockers and calcium channel blockers: increase risk of bradycardia and hypotension.
  • CYP3A4 inhibitors (e.g., ketoconazole): can raise plasma lidocaine levels.
  • Monoamine oxidase inhibitors: may enhance central nervous system toxicity.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs: may increase bleeding risk.
  • General anesthetics (e.g., propofol): additive CNS depression.
  • Diuretics (e.g., furosemide): may affect plasma protein binding.

Frequently Asked Questions

Lidocain Aguettant is a lidocaine‑based local anesthetic supplied as a sterile solution for infiltration, intradermal and intravenous regional anesthesia, commonly employed in minor surgical procedures, dental work, and other settings requiring short‑duration nerve block.

Lidocaine blocks voltage‑gated sodium channels in neuronal membranes, preventing the rapid influx of sodium ions needed for depolarization. This reversible inhibition stops the generation and propagation of nerve impulses, producing a temporary loss of sensation in the targeted area.

The specific dose is determined by the prescribing clinician based on the procedure, patient weight, and site of administration. Standard practice follows established maximum recommended limits for infiltration, intradermal or intravenous regional techniques, and the prescriber sets the exact amount.

Safety data are limited; lidocaine crosses the placenta and may be present in breast milk. Use is permitted only when the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by the treating physician.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with other amide‑type agents such as bupivacaine, lidocaine has a faster onset but a shorter duration of action, making it suitable for procedures requiring rapid anesthesia and quick recovery. Its toxicity profile is well‑characterized, and it is less cardiotoxic than some longer‑acting alternatives.

Store at ambient temperature, preferably below 25 °C, in the original sealed container. Protect from direct sunlight, moisture and extreme temperatures. Do not freeze. Inspect the solution for particulate matter or discoloration before use and discard if any abnormalities are observed.

The product is supplied as a sterile solution for injection. It can be administered by infiltration into the tissue surrounding the surgical site, intradermally for diagnostic or minor procedures, or intravenously as part of a regional (Bier) block. Administration technique follows standard aseptic practices and the dosage recommended by the prescriber.

Serious adverse events include systemic toxicity manifesting as central nervous system seizures, cardiac arrhythmias, hypotension, methemoglobinemia, and severe allergic reactions such as anaphylaxis. These risks increase with excessive dosing, rapid intravascular injection, or when combined with interacting medications, and require immediate medical intervention.

Individuals with a known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid this product. Caution is also advised for patients with severe cardiac conduction disorders, uncontrolled epilepsy, or those receiving medications that significantly raise lidocaine plasma levels. Use is contraindicated in such cases unless an alternative has been evaluated and approved by a qualified clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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