Product image of Lidocain Hwi Pharma (Lidocaine) supplied by GNH India

Lidocain Hwi Pharma

Active Ingredient:
Lidocaine
Origin:
EU

Lidocain Hwi Pharma (Lidocaine)

Lidocaine, the active ingredient in Lidocain Hwi Pharma, is a local anesthetic presented as a rectal formulation for local anesthesia and analgesia. It is used to numb tissue and relieve pain in the rectal area.
GNH India supplies Lidocain Hwi Pharma as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dr. Kade Pharmazeutische Fabrik Gmbh

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Indications & Clinical Uses

Lidocaine is a local anesthetic that works on peripheral nerves to provide temporary loss of sensation.

  • Rectal anesthesia: provides localized numbness for minor procedures or examinations of the rectal mucosa.
  • Analgesia: reduces discomfort associated with hemorrhoidal disease or proctologic irritation.
  • Pain relief: offers short‑term relief of acute rectal pain following minor trauma or surgery.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the rapid influx of sodium ions required for depolarisation. This inhibition stops the generation and propagation of nerve impulses, resulting in reversible loss of sensation in the area where the drug is applied.

Side Effects

Lidocaine may cause a range of adverse reactions, most of which are mild and localized.

Common Side Effects

  • Local irritation: mild burning, itching or redness at the application site.
  • Nausea: occasional feeling of queasiness after absorption.
  • Dizziness: transient light‑headedness.
  • Headache: mild headache in some patients.

Serious or Rare Side Effects

  • Systemic toxicity: seizures, cardiac arrhythmia or hypotension with excessive absorption.
  • Allergic reaction: rash, urticaria, angioedema or anaphylaxis.
  • Methemoglobinemia: rare blood disorder causing reduced oxygen delivery.
  • Severe local tissue damage: ulceration or necrosis if applied to compromised mucosa.

Precautions & Warnings

Before using Lidocain Hwi Pharma, consider the following safety measures.

  • Allergy assessment: confirm the patient has no known hypersensitivity to lidocaine or other amide‑type anesthetics.
  • Dose limitation: avoid exceeding the maximum recommended amount for rectal administration.
  • Hepatic impairment: use with caution in patients with liver dysfunction, as metabolism may be reduced.
  • Cardiac conditions: monitor patients with conduction disorders or arrhythmias.
  • Concomitant local anesthetics: avoid simultaneous use to prevent additive toxicity.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Lidocaine can interact with other medicines, altering its safety profile.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): increase risk of cardiotoxicity.
  • Beta‑blockers: may enhance lidocaine’s negative inotropic effects.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): raise systemic lidocaine concentrations.

Moderate Interactions (Monitor Closely)

  • Other local anesthetics: additive neuro‑ and cardiotoxic effects.
  • Diuretics (e.g., furosemide): may increase plasma levels by reducing clearance.
  • General anesthetics (e.g., propofol): potential potentiation of central nervous system depression.

Frequently Asked Questions

Lidocain Hwi Pharma is a lidocaine‑based product formulated for rectal administration. It is used to provide local anesthesia and short‑term analgesia for minor procedures, examinations, or discomfort in the rectal area, such as hemorrhoidal treatment or proctologic diagnostics.

Lidocaine blocks voltage‑gated sodium channels on nerve membranes, preventing the rapid influx of sodium ions needed for depolarisation. This stops the initiation and conduction of nerve impulses, resulting in reversible loss of sensation and pain relief at the site of application.

The appropriate dose is determined by the prescribing healthcare professional based on the specific procedure, patient age, weight, and clinical condition. Dosage instructions are provided on the product label and must be followed exactly as directed by the prescriber.

Safety data for rectal lidocaine in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant, and this decision must be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lidocaine is an amide‑type local anesthetic with a rapid onset and moderate duration of action. Compared with ester‑type agents such as procaine, lidocaine generally offers a more predictable pharmacokinetic profile, lower allergenic potential, and broader clinical use for both topical and injectable applications.

Lidocain Hwi Pharma should be stored at room temperature, below 25 °C, in its original container. Keep the product away from moisture, direct sunlight and extreme heat. Ensure the packaging remains sealed until use to maintain product integrity.

The product is applied rectally, typically as a gel, ointment or suppository, according to the prescribing information. The healthcare professional will clean the area, apply the appropriate amount, and allow the formulation to remain in place for the recommended contact time before proceeding with the procedure.

Serious risks include systemic toxicity leading to seizures, cardiac arrhythmias, or hypotension, especially if excessive amounts are absorbed. Rare but severe allergic reactions such as anaphylaxis and methemoglobinemia may also occur. Immediate medical attention is required if any of these symptoms develop.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid this product. It is also contraindicated in individuals with severe cardiac conduction disorders, uncontrolled heart failure, or those taking medications that may cause dangerous interactions without close monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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