Product image of Lidocaina Cloridrato Galenica Senese (Lidocaine Hydrochloride) supplied by GNH India

Lidocaina Cloridrato Galenica Senese

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocaina Cloridrato Galenica Senese (Lidocaine Hydrochloride)

Lidocaine Hydrochloride, the active ingredient in Lidocaina Cloridrato Galenica Senese, is a local anesthetic (amide type) presented as a sterile injectable solution for intramuscular and intravenous use. It provides reversible nerve impulse blockade for procedures requiring regional or systemic analgesia in adult patients.

GNH India supplies Lidocaina Cloridrato Galenica Senese as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU GMP standards and offers reliable logistics for global distribution.

Manufacturer / TM Owner

Industria Farmaceutica Galenica Senese S.R.L..

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Indications & Clinical Uses

Lidocaine Hydrochloride is used in clinical settings to achieve local anesthesia and to manage certain cardiac rhythm disturbances.

  • Minor surgical procedures: provides local anesthesia to facilitate pain‑free operation.
  • Diagnostic procedures: enables painless tissue sampling or imaging studies.
  • Nerve block anesthesia: produces regional numbness for limb or trunk surgeries.
  • Ventricular arrhythmia management: stabilizes cardiac electrical activity during acute episodes.

How It Works

  • Lidocaine Hydrochloride blocks voltage‑gated sodium channels on neuronal membranes, preventing the rapid influx of sodium ions required for depolarization. This reversible inhibition stops the initiation and propagation of nerve impulses, producing loss of sensation in the targeted area and, when administered systemically, can suppress abnormal cardiac electrical activity.

Side Effects

Adverse reactions to lidocaine injection vary in frequency and severity.

Common Side Effects

  • Transient numbness at the injection site.
  • Mild dizziness or light‑headedness.
  • Metallic taste in the mouth.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis).
  • Cardiac arrhythmias, including ventricular tachycardia.
  • Seizures or central nervous system toxicity.

Precautions & Warnings

Lidocaine should be used with careful assessment of patient-specific factors and potential drug interactions.

  • Pregnancy: safety not established; use only if benefit outweighs risk.
  • Breastfeeding: unknown; consider potential infant exposure.
  • Cardiac disease: monitor for arrhythmias, especially in patients with conduction abnormalities.
  • Central nervous system disorders: use cautiously; risk of seizures may increase.
  • Concomitant medications: review for drugs that affect lidocaine metabolism.
  • Store below 25°C: keep in original container, protect from light and moisture.

Avoid Interactions

Lidocaine may interact with several medications, requiring assessment of clinical relevance.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may potentiate cardiotoxicity.
  • Other local anesthetics: additive toxicity risk.
  • CYP1A2 or CYP3A4 inhibitors (e.g., cimetidine, erythromycin): increase plasma lidocaine levels.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers (e.g., propranolol): may enhance bradycardia.
  • Calcium channel blockers (e.g., verapamil): may affect cardiac conduction.
  • Diuretics (e.g., furosemide): may alter plasma protein binding.

Frequently Asked Questions

Lidocaina Cloridrato Galenica Senese is a sterile injectable form of lidocaine hydrochloride used to provide local anesthesia for minor surgical or diagnostic procedures, to perform regional nerve blocks, and to manage acute ventricular arrhythmias when administered intravenously.

Lidocaine hydrochloride blocks voltage‑gated sodium channels on nerve and cardiac cells, preventing the rapid influx of sodium that initiates action potentials. This reversible blockade stops nerve impulse transmission, producing localized numbness, and can suppress abnormal cardiac electrical activity when given systemically.

The appropriate dose of lidocaine is determined by the prescribing clinician based on the specific procedure, patient weight, age, and clinical condition. Dosing may vary for local infiltration, nerve block, or intravenous anti‑arrhythmic use, and should always follow the prescriber’s instructions.

Safety data for lidocaine during pregnancy and lactation are limited. It is classified as category C, meaning it should be used only if the potential benefit justifies any potential risk to the fetus. Breastfeeding mothers should consider possible infant exposure and discuss risks with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

The most common alternative local anesthetic is bupivacaine, which has a longer duration of action but a higher risk of cardiotoxicity at comparable doses. Lidocaine offers a shorter onset and duration, making it suitable for procedures requiring rapid recovery, while bupivacaine is preferred when prolonged anesthesia is needed.

Lidocaina Cloridrato should be stored below 25 °C in its original packaging, protected from light and moisture. Do not freeze the solution. Before use, inspect the vial for particulate matter or discoloration and discard if any abnormalities are observed.

The product is administered by a qualified healthcare professional via intramuscular or intravenous injection. The injection site and technique depend on the intended use—local infiltration for minor procedures, regional nerve block for targeted anesthesia, or slow intravenous infusion for cardiac arrhythmia control.

Serious risks include severe allergic reactions (anaphylaxis), cardiac arrhythmias such as ventricular tachycardia, and central nervous system toxicity leading to seizures. Immediate medical attention is required if any of these events occur during or after administration.

Lidocaine is contraindicated in patients with known hypersensitivity to amide‑type local anesthetics, those with severe heart block or uncontrolled arrhythmias, and individuals with significant hepatic impairment that could impair drug metabolism. Caution is also advised for patients with epilepsy or other seizure disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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