Product image of Lidocaina Cloridrato Monico (Lidocaine Hydrochloride) supplied by GNH India

Lidocaina Cloridrato Monico

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocaina Cloridrato Monico (Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Lidocaina Cloridrato Monico, is a local anesthetic (amide type) presented as a sterile injectable solution for intravenous use. It provides reversible nerve impulse blockade for minor surgical procedures, regional nerve blocks, and ventricular arrhythmia management in adult patients.

GNH India supplies Lidocaina Cloridrato Monico as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. The company adheres to EU GMP standards and provides reliable logistics for clinical and institutional customers. Products are shipped with full documentation to meet regulatory requirements across regions.

Manufacturer / TM Owner

Monico S.P.A.

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Indications & Clinical Uses

  • Lidocaine is employed in clinical settings to achieve local anesthesia and to control certain cardiac arrhythmias.
  • Minor surgical procedures: provides rapid onset surface anesthesia for incision and suturing.
  • Peripheral nerve blocks: enables regional anesthesia for limb surgeries and pain control.
  • Ventricular arrhythmias: stabilizes cardiac electrical activity during acute episodes.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels in neuronal and cardiac cell membranes, preventing the rapid influx of sodium ions required for depolarization. By stabilizing the inactive state of the channel, it inhibits the initiation and propagation of action potentials, resulting in loss of sensation in the targeted area and suppression of abnormal cardiac conduction. The effect is dose‑dependent and reversible as the drug dissociates from the channel.

Side Effects

Lidocaine may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Transient tingling or numbness at the injection site
  • Mild dizziness or light‑headedness
  • Nausea or metallic taste

Serious or Rare Side Effects

  • Anaphylactic reaction with rash, bronchospasm or shock
  • Cardiac conduction disturbances (bradycardia, heart block, ventricular arrhythmia)
  • Central nervous system toxicity (seizures, confusion, loss of consciousness)

Precautions & Warnings

When using lidocaine, clinicians should observe several safety measures.

  • Dose adjustment: individualize dose based on patient weight, cardiac status and concomitant medications
  • Cardiovascular monitoring: observe heart rate and rhythm during IV administration
  • Avoid rapid bolus: administer slowly to reduce risk of CNS toxicity
  • Use with caution in patients with hepatic impairment
  • Avoid in patients with known hypersensitivity to amide local anesthetics
  • Store at ambient temperature: keep in original container, protect from light and moisture

Avoid Interactions

Lidocaine can interact with other medicines, requiring attention to potential additive effects.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): additive cardiac conduction effects
  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): increase lidocaine plasma levels
  • Beta‑blockers: may enhance bradycardia

Moderate Interactions (Monitor Closely)

  • Class II antiarrhythmics (e.g., amiodarone): may increase toxicity
  • General anesthetics (e.g., propofol, volatile agents): synergistic CNS depression
  • Diuretics (e.g., furosemide): may alter plasma protein binding

Frequently Asked Questions

Lidocaina Cloridrato Monico contains lidocaine hydrochloride and is used to provide local anesthesia for minor surgical procedures, to perform regional nerve blocks, and to manage ventricular arrhythmias in adult patients under professional supervision.

Lidocaine blocks voltage‑gated sodium channels on nerve and cardiac cells, preventing the rapid influx of sodium ions needed for depolarisation. This reversible blockade stops the propagation of action potentials, producing loss of sensation in the targeted area and stabilising abnormal cardiac electrical activity.

The appropriate dose is determined by the prescribing clinician based on the specific indication, patient characteristics, and clinical setting. Dosage regimens are not standardized in public literature and must follow the prescriber’s order and local regulatory guidance.

Safety data for lidocaine in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by the treating physician in consultation with the patient.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lidocaine is an amide‑type local anesthetic with a rapid onset and moderate duration, making it suitable for many short‑procedures. Compared with ester‑type agents such as procaine, lidocaine has a lower risk of allergic reactions and a more predictable pharmacokinetic profile.

Lidocaina Cloridrato Monico should be stored at ambient temperature, preferably below 25 °C, in its original container. Protect the solution from light, moisture and extreme temperatures to maintain stability and potency.

The product is supplied as a sterile injectable solution for intravenous administration. It is administered by a qualified healthcare professional, typically as a slow infusion or controlled bolus, according to the prescriber’s instructions and institutional protocols.

Serious adverse events include anaphylactic reactions, severe cardiac conduction disturbances such as bradycardia or heart block, and central nervous system toxicity that may present as seizures, confusion or loss of consciousness. Immediate medical attention is required if these occur.

Patients with known hypersensitivity to lidocaine or other amide‑type local anesthetics, those with severe hepatic impairment, and individuals with certain cardiac conduction disorders should avoid this medication unless a risk‑benefit assessment justifies its use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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