Product image of Lidocaina Cloridrato S.A.L.F. (Lidocaine Hydrochloride Monohydrate) supplied by GNH India

Lidocaina Cloridrato S.A.L.F.

Active Ingredient:
Lidocaine Hydrochloride Monohydrate
Origin:
EU

Lidocaina Cloridrato S.A.L.F. (Lidocaine Hydrochloride Monohydrate)

Lidocaine hydrochloride, the active ingredient in Lidocaina Cloridrato S.A.L.F., is a local anesthetic presented as a sterile injectable solution for intravenous use. It provides rapid, reversible loss of sensation for surgical procedures, regional nerve blocks, and analgesia.
GNH India supplies Lidocaina Cloridrato S.A.L.F. as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

S.A.L.F. Spa Laboratorio Farmacologico

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Indications & Clinical Uses

Lidocaine hydrochloride is employed in the management of pain and sensation within the surgical and procedural setting.

  • Surgical procedures: provides localized numbness to facilitate operative interventions.
  • Regional anesthesia: enables nerve block techniques for limb or trunk anesthesia.
  • Analgesia: offers pain relief during minor procedures or the postoperative period.

How It Works

  • Lidocaine hydrochloride exerts its effect by binding to and blocking voltage‑gated sodium channels on neuronal membranes, inhibiting the rapid influx of sodium ions required for the initiation and propagation of action potentials. This blockade prevents the transmission of pain signals from the peripheral site to the central nervous system, resulting in temporary loss of sensation.

Side Effects

Adverse reactions may occur with intravenous lidocaine administration.

Common Side Effects

  • Dizziness or light‑headedness.
  • Metallic taste in the mouth.
  • Numbness or tingling at the injection site.
  • Mild hypotension.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Cardiac arrhythmias, including ventricular tachycardia.
  • Central nervous system toxicity manifesting as seizures.

Precautions & Warnings

When using Lidocaina Cloridrato S.A.L.F., clinicians should consider several safety measures.

  • Assess cardiac history: avoid rapid IV bolus in patients with conduction disorders.
  • Monitor blood pressure: watch for hypotension during administration.
  • Avoid in patients with known lidocaine allergy.
  • Use caution in hepatic impairment: reduced metabolism may increase exposure.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Lidocaine may interact with other medications, requiring careful assessment.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may increase lidocaine plasma levels leading to toxicity.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): can raise concentrations.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may enhance cardiac depressant effects.
  • Diuretics: may alter plasma protein binding.
  • Other local anesthetics: additive toxicity risk.

Frequently Asked Questions

It is a sterile injectable solution of lidocaine hydrochloride used as a local anesthetic to provide numbness during surgical procedures, enable regional nerve blocks, and offer analgesia for minor interventions. The prescriber determines the appropriate use based on clinical need.

Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the rapid influx of sodium ions that initiates an action potential. By inhibiting nerve impulse propagation, it temporarily halts transmission of pain signals from the site of administration to the central nervous system.

The dosage is individualized; a qualified healthcare professional selects the amount, concentration, and rate of intravenous administration based on the patient’s age, weight, procedure type, and clinical response. No fixed regimen is provided in public literature.

Safety data are limited; lidocaine crosses the placenta and is excreted in breast milk in small amounts. Use is generally reserved for situations where the benefit outweighs potential risk, and only under medical supervision.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Lidocaine has a rapid onset (1–2 minutes) and intermediate duration (30–120 minutes), making it suitable for many procedures. Compared with bupivacaine, it has a shorter duration and lower cardiotoxicity, while offering faster recovery. Choice depends on required anesthesia depth, procedure length, and patient risk factors.

Store at ambient temperature, preferably below 25 °C, in the original sealed container. Protect from moisture, direct sunlight and extreme temperatures. Do not freeze. Ensure the vial remains upright and check the expiry date before use.

The solution is administered intravenously by a qualified healthcare professional. It may be given as a slow bolus or continuous infusion, depending on the clinical setting. Proper aseptic technique and appropriate monitoring of vital signs are essential during administration.

Serious adverse events include anaphylactic reactions, cardiac arrhythmias such as ventricular tachycardia, and central nervous system toxicity leading to seizures. These risks increase with rapid high‑dose administration or in patients with pre‑existing cardiac or hepatic impairment, requiring immediate medical intervention.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid it. It is also contraindicated in individuals with severe heart block, uncontrolled epilepsy, or significant hepatic dysfunction where metabolism is impaired. Clinical judgment is required for other high‑risk groups.

Published by

GNH India Pharmaceuticals Limited

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Last updated:

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