Product image of Lidocaina Kabi (Lidocaine Hydrochloride Monohydrate) supplied by GNH India

Lidocaina Kabi

Active Ingredient:
Lidocaine Hydrochloride Monohydrate
Origin:
EU

Lidocaina Kabi (Lidocaine Hydrochloride Monohydrate)

Lidocaine, the active ingredient in Lidocaina Kabi, is a local anesthetic (amide) presented as a sterile solution for epidural, intramuscular and intravenous use. It provides reversible nerve block for minor surgical procedures and analgesia in adult patients.

GNH India supplies Lidocaina Kabi as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Fresenius Kabi Italia S.R.L.

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Indications & Clinical Uses

Lidocaina Kabi is a local anesthetic indicated for several procedural and analgesic pathways.

  • Minor surgical procedures: provides local anesthesia for incision and minor tissue manipulation.
  • Epidural analgesia: delivers regional pain relief during labor or postoperative periods.
  • Intravenous regional anesthesia (Bier block): produces rapid, reversible anesthesia of a limb for short surgical interventions.

How It Works

  • Lidocaine reversibly blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of action potentials. By stabilising the neuronal membrane, it inhibits nerve impulse transmission, resulting in loss of sensation in the targeted area without affecting surrounding tissues.

Side Effects

Lidocaina Kabi may cause a range of adverse reactions.

Common Side Effects

  • Transient numbness or tingling at the injection site.
  • Dizziness or light‑headedness.
  • Metallic taste in the mouth.
  • Mild hypotension.
  • Nausea or mild vomiting.
  • Localized swelling or erythema.

Serious or Rare Side Effects

  • Seizures or convulsions.
  • Cardiac arrhythmias, including ventricular tachycardia.
  • Severe hypotension or cardiovascular collapse.
  • Allergic reactions such as urticaria, angioedema, or anaphylaxis.
  • Methemoglobinemia.
  • Respiratory depression.

Precautions & Warnings

Before using Lidocaina Kabi, consider the following safety measures.

  • Allergy assessment: confirm no known hypersensitivity to amide‑type local anesthetics.
  • Cardiac monitoring: observe patients with pre‑existing heart disease or conduction abnormalities.
  • Dose calculation: adjust dose based on patient weight, age, and comorbidities.
  • Concurrent medications: review for drugs that may increase lidocaine toxicity.
  • Injection technique: use proper aseptic technique to avoid infection.
  • Store at controlled room temperature: keep in original container, protect from light, do not freeze.

Avoid Interactions

Lidocaina Kabi can interact with several medicines; awareness helps prevent toxicity.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may increase systemic lidocaine levels.
  • Beta‑adrenergic blockers: can exacerbate bradycardia and hypotension.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may raise plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Other local anesthetics: additive neuro‑ and cardiotoxic effects.
  • Diuretics (e.g., furosemide): may reduce plasma protein binding, increasing free lidocaine.
  • General anesthetics (e.g., propofol, volatile agents): may potentiate central nervous system depression.

Frequently Asked Questions

Lidocaina Kabi is a sterile lidocaine preparation used to provide local or regional anesthesia. It is commonly employed for minor surgical procedures, epidural analgesia during labor or postoperative care, and intravenous regional (Bier) blocks for short‑duration limb surgeries.

Lidocaine blocks voltage‑gated sodium channels on nerve membranes, preventing the rapid influx of sodium ions that initiates an action potential. This stabilises the neuronal membrane and stops the transmission of pain signals, producing a reversible loss of sensation in the targeted area.

The dose of Lidocaina Kabi is determined by the prescribing clinician based on the intended procedure, patient weight, age, and overall health. Only a qualified healthcare professional should calculate and administer the appropriate amount.

Safety data for lidocaine in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Lidocaine has a rapid onset and moderate duration, making it suitable for short‑ to medium‑length procedures. Compared with bupivacaine, which offers a longer duration but slower onset, lidocaine is preferred when quick recovery of sensation is desired. Its safety profile is well‑established, though toxicity thresholds differ among agents.

Lidocaina Kabi should be stored at controlled room temperature, away from direct sunlight and moisture. Keep the vial in its original packaging, protect it from freezing, and ensure the seal remains intact until use. Do not refrigerate unless specifically instructed by the manufacturer.

The product is supplied as a sterile injectable solution and may be administered epidurally, intramuscularly, or intravenously, depending on the clinical indication. Administration must be performed by a qualified healthcare professional using aseptic technique and appropriate dosing calculations.

Serious adverse events include central nervous system toxicity such as seizures, cardiovascular effects like arrhythmias or severe hypotension, and rare allergic reactions ranging from urticaria to anaphylaxis. Prompt recognition and supportive management are essential if these events occur.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid the product. It is also contraindicated in individuals with severe heart block, uncontrolled epilepsy, or significant hepatic impairment without careful medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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