Product image of Lidocaine 2% Fresenius Kabi (Lidocaine Hydrochloride Monohydrate) supplied by GNH India

Lidocaine 2% Fresenius Kabi

Active Ingredient:
Lidocaine Hydrochloride Monohydrate
Origin:
EU

Lidocaine 2% Fresenius Kabi (Lidocaine Hydrochloride Monohydrate)

Lidocaine, the active ingredient in Lidocaine 2% Fresenius Kabi, is a local anesthetic presented as a 2% solution for injection for epidural, intramuscular, and intravenous use. It provides rapid, reversible loss of sensation and pain relief in a variety of clinical procedures.
GNH India supplies Lidocaine 2% Fresenius Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Fresenius Kabi Polska Sp. Z O.O.

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Indications & Clinical Uses

  • Lidocaine is a local anesthetic used to block nerve conduction for procedural and postoperative pain management.
  • Local anesthesia: provides rapid onset numbness for minor surgical or diagnostic procedures.
  • Epidural analgesia: delivers analgesia during labor, surgery, or postoperative period.
  • Regional nerve block: facilitates targeted pain control for limb or trunk surgeries.
  • Dental procedures: numbs oral tissues for dental work.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the rapid influx of sodium ions required for depolarization. By inhibiting action potential initiation and propagation, it interrupts nerve impulse transmission, resulting in reversible loss of sensation in the treated area.

Side Effects

Lidocaine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Transient burning or stinging at the injection site
  • Mild dizziness or light‑headedness
  • Nausea or vomiting
  • Tinnitus (ringing in the ears)

Serious or Rare Side Effects

  • Cardiac arrhythmias, including ventricular tachycardia
  • Central nervous system seizures
  • Methemoglobinemia leading to cyanosis
  • Severe allergic reactions such as anaphylaxis

Precautions & Warnings

When using Lidocaine 2% solution, clinicians should observe several safety measures.

  • Allergy assessment: verify no known hypersensitivity to amide‑type local anesthetics.
  • Cardiovascular status: avoid rapid high‑dose administration in patients with conduction disorders.
  • CNS disorders: use cautiously in patients with a history of seizures.
  • Pregnancy: consider risk‑benefit; data are limited.
  • Elderly or hepatic impairment: dose may need adjustment.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Lidocaine can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may potentiate cardiotoxicity.
  • Beta‑blockers: increase risk of bradycardia and hypotension.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may raise lidocaine plasma levels.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs: may increase bleeding risk.
  • General anesthetics (e.g., propofol): additive CNS depression.
  • Other local anesthetics: cumulative toxicity risk.

Frequently Asked Questions

Lidocaine 2% Fresenius Kabi is a sterile solution for injection that provides local anesthesia, epidural analgesia, and regional nerve block. It is employed in surgical, obstetric, dental, and diagnostic procedures to produce rapid, reversible loss of sensation and pain control.

Lidocaine works by blocking voltage‑gated sodium channels on nerve membranes, which stops the influx of sodium ions needed for action potential generation. This inhibition prevents nerve impulse propagation, resulting in temporary loss of sensation in the area where it is administered.

The appropriate dose of Lidocaine 2% is determined by the prescribing clinician based on the intended route, procedure, patient weight, age, and comorbidities. Healthcare professionals calculate the amount required to achieve effective anesthesia while staying within safety limits.

Lidocaine is classified as pregnancy category unknown; limited data exist. It should be used during pregnancy or lactation only when the potential benefit justifies any potential risk to the fetus or infant, and under close medical supervision.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Lidocaine has a faster onset of action but a shorter duration compared with bupivacaine, which provides longer-lasting analgesia but takes longer to take effect. Choice between them depends on the clinical need for rapid onset versus prolonged block, as well as safety considerations for cardiac toxicity.

Lidocaine 2% solution should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect it from direct sunlight, moisture, and freezing. Inspect the vial for particulate matter before use and discard if the solution appears discolored.

The solution is administered by injection via epidural, intramuscular, or intravenous routes, depending on the clinical indication. Administration techniques follow standard aseptic procedures, and the volume injected is calculated by the prescriber to achieve the desired anesthetic effect.

Serious risks include cardiac arrhythmias, seizures, methemoglobinemia, and severe allergic reactions such as anaphylaxis. Early signs of toxicity—such as tinnitus, metallic taste, or circumoral numbness—should prompt immediate medical evaluation.

Patients with known hypersensitivity to lidocaine or other amide‑type local anesthetics, those with severe heart block, uncontrolled epilepsy, or significant hepatic impairment should avoid its use unless a specialist determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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