Product image of Lidocaïne Vaselinecrème Tiofarma (Lidocaine) supplied by GNH India

Lidocaïne Vaselinecrème Tiofarma

Active Ingredient:
Lidocaine
Origin:
EU

Lidocaïne Vaselinecrème Tiofarma (Lidocaine)

Lidocaine, the active ingredient in Lidocaïne Vaselinecrème Tiofarma, is a local anesthetic presented as a vaseline cream for rectal use. It provides topical pain relief and is employed in conditions such as hemorrhoids, anal fissures and other sources of local rectal discomfort.

GNH India supplies Lidocaïne Vaselinecrème Tiofarma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Tiofarma B.V.

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Indications & Clinical Uses

  • Lidocaine is a local anesthetic that blocks peripheral nerve sodium channels to relieve pain in several anorectal conditions.
  • Hemorrhoids: reduces pain and discomfort associated with hemorrhoidal disease.
  • Anal fissures: provides topical analgesia that facilitates healing of fissures.
  • Local pain relief: alleviates minor rectal irritation or procedural discomfort.

How It Works

  • Lidocaine binds to voltage‑gated sodium channels on neuronal membranes, stabilising the inactive state of the channel and preventing the rapid influx of sodium ions. This inhibition blocks the generation and propagation of nerve impulses, resulting in a reversible loss of sensation in the area of application and providing local anesthesia.

Side Effects

Lidocaine cream may cause local and systemic reactions, ranging from mild irritation to rare severe events.

Common Side Effects

  • Mild skin irritation at the application site
  • Burning or stinging sensation
  • Itching or pruritus
  • Redness or erythema
  • Swelling or edema
  • Dryness of the treated area

Serious or Rare Side Effects

  • Allergic reactions such as urticaria or angioedema
  • Severe dermatitis or contact eczema
  • Systemic toxicity presenting as CNS symptoms (dizziness, seizures)
  • Methemoglobinemia (rare)
  • Cardiovascular disturbances (arrhythmia, hypotension)

Precautions & Warnings

  • When using Lidocaïne Vaselinecrème Tiofarma, follow these safety measures.
  • Application: apply a thin layer only to the affected rectal area.
  • Avoid: do not use on extensive broken skin or mucosa beyond the intended site.
  • Contraindication: discontinue if known hypersensitivity to lidocaine or other amide anesthetics.
  • Pregnancy: safety not established; use only if potential benefit outweighs risk.
  • Children: exercise caution in pediatric patients and adjust usage as directed.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lidocaine can interact with other medicines that affect sodium channels or its metabolism.

Major Interactions (Avoid)

  • Concurrent use with other topical anesthetics containing lidocaine (risk of cumulative toxicity).
  • Co‑administration with class I antiarrhythmics (e.g., quinidine) may increase systemic lidocaine levels.
  • Strong CYP3A4 inhibitors could raise systemic exposure.

Moderate Interactions (Monitor Closely)

  • Use with other sodium‑channel blockers (e.g., mexiletine) may have additive effects.
  • Combination with vasoconstrictors may alter local absorption.
  • Caution when combined with other drugs that lower seizure threshold.

Frequently Asked Questions

Lidocaïne Vaselinecrème Tiofarma is a topical lidocaine formulation designed for rectal application. It is used to provide local pain relief in anorectal conditions such as hemorrhoids, anal fissures and minor procedural discomfort, helping to reduce pain and facilitate healing.

Lidocaine works by binding to voltage‑gated sodium channels on nerve cells, stabilising them in an inactive state. This blocks the rapid influx of sodium ions needed for nerve impulse generation, resulting in a reversible loss of sensation and analgesia at the site where the cream is applied.

The appropriate dose and frequency are determined by the prescribing healthcare professional based on the severity of the condition, patient age and other clinical factors. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety data for rectal lidocaine cream in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lidocaïne Vaselinecrème Tiofarma contains lidocaine, an amide‑type local anesthetic, which offers rapid onset and reliable analgesia. Compared with benzocaine or prilocaine creams, lidocaine generally provides a longer duration of action and a lower risk of methemoglobinemia, making it a preferred choice for anorectal applications.

Store the cream at room temperature, below 25 °C, in its original packaging. Protect it from moisture, direct sunlight and extreme temperatures. Keep the container tightly closed when not in use to maintain product stability.

The cream is applied rectally using a clean fingertip or applicator. A thin layer is spread over the affected area as directed by the prescriber, typically after gentle cleaning of the region. Do not insert the cream deep into the anal canal unless instructed.

Serious risks include allergic reactions such as urticaria or angioedema, severe dermatitis, systemic toxicity manifesting as central nervous system symptoms (e.g., dizziness, seizures), and rare cases of methemoglobinemia. Any signs of systemic effects or severe local reactions should prompt immediate medical attention.

Individuals with a known hypersensitivity to lidocaine, other amide‑type local anesthetics, or any component of the formulation should avoid using this product. It is also contraindicated in patients with severe liver disease that may impair lidocaine metabolism, unless a healthcare professional advises otherwise.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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