Product image of Lidocaïne Vaselinecrème Dmb (Lidocaine) supplied by GNH India

Lidocaïne Vaselinecrème Dmb

Active Ingredient:
Lidocaine
Origin:
EU

Lidocaïne Vaselinecrème Dmb (Lidocaine)

Lidocaine, the active ingredient in Lidocaïne Vaselinecrème Dmb, is a local anesthetic presented as a cream for rectal use. It provides topical analgesia for anorectal discomfort in adult patients.
GNH India supplies Lidocaïne Vaselinecrème Dmb as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Tiofarma B.V.

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Indications & Clinical Uses

  • Lidocaine cream is a topical local anesthetic used to relieve pain in the anorectal region.
  • Hemorrhoidal pain: reduces discomfort associated with internal and external hemorrhoids.
  • Anal fissure pain: eases burning and stinging during bowel movements.
  • Post‑procedural anorectal discomfort: alleviates pain after minor surgical or diagnostic procedures in the anal canal.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of nerve impulses. By stabilising the neuronal membrane, it reduces the transmission of pain signals from the application site, resulting in localized loss of sensation without affecting systemic nerve function.

Side Effects

Lidocaine cream may cause local and systemic adverse reactions.

Common Side Effects

  • Burning or stinging at the application site
  • Mild itching or erythema
  • Localized swelling or edema
  • Sensation of coldness or tingling
  • Dryness or flaking of the skin
  • Transient headache

Serious or Rare Side Effects

  • Systemic toxicity (e.g., dizziness, seizures, cardiac arrhythmia)
  • Allergic reactions (e.g., rash, urticaria, angioedema)
  • Methemoglobinemia
  • Severe skin necrosis or ulceration
  • Persistent numbness beyond the intended area
  • Vision disturbances if absorbed in large amounts

Precautions & Warnings

  • Before using Lidocaïne Vaselinecrème Dmb, consider the following safety measures.
  • Allergy assessment: verify no known hypersensitivity to lidocaine or related amide anesthetics.
  • Avoid broken skin: do not apply to ulcerated or severely inflamed mucosa.
  • Limit application area: restrict use to the recommended surface area to prevent systemic absorption.
  • Do not exceed recommended amount: follow prescriber instructions regarding quantity and frequency.
  • Monitor for systemic signs: watch for dizziness, tinnitus, or cardiac symptoms.
  • Store at room temperature: keep in the original container, protect from moisture and direct heat.

Avoid Interactions

Lidocaine may interact with other medicines; awareness of these interactions helps maintain safety.

Major Interactions (Avoid)

  • Amiodarone: may increase lidocaine plasma levels, raising toxicity risk.
  • Class I anti‑arrhythmics (e.g., quinidine, procainamide): additive cardiac conduction effects.
  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): can reduce lidocaine metabolism.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers (e.g., propranolol): may enhance bradycardic effects.
  • Other local anesthetics: cumulative toxicity if used concurrently.
  • Anticonvulsants (e.g., phenytoin): may alter seizure threshold when lidocaine systemic levels rise.

Frequently Asked Questions

Lidocaïne Vaselinecrème Dmb is a rectally administered lidocaine cream designed to provide topical analgesia for anorectal conditions such as hemorrhoidal pain, anal fissures, and discomfort following minor procedures. It works by numbing the affected area, helping to reduce pain during bowel movements and improving patient comfort.

Lidocaine blocks voltage‑gated sodium channels on peripheral nerve membranes, preventing the initiation and propagation of pain signals. By stabilising neuronal membranes in the rectal mucosa, the cream produces a localized loss of sensation without affecting systemic nerve function, thereby relieving pain at the site of application.

The specific dose and frequency are determined by the prescribing healthcare professional based on the patient’s condition, severity of symptoms, and treatment goals. The prescriber will provide instructions on the amount of cream to apply, the number of applications per day, and the duration of therapy.

Safety data for rectal lidocaine cream in pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits against any possible risks before prescribing it to pregnant or nursing individuals. If used, it should be applied only as directed and under medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. The sales team will then respond with pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Lidocaïne Vaselinecrème Dmb offers a topical, rectal formulation that provides localized analgesia without the need for injections, unlike some other lidocaine preparations. Compared with oral analgesics, it delivers pain relief directly at the site of discomfort, reducing systemic exposure and associated side effects. Its cream base also allows for easy application and patient comfort.

Store the cream at room temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture, direct sunlight, and excessive heat. Ensure the container is tightly closed when not in use to maintain product stability.

The cream is applied rectally using a gloved finger or applicator as directed by the prescriber. The recommended amount is spread gently over the affected area, avoiding excessive pressure. Application should be performed after thorough hand hygiene and following any specific instructions regarding timing relative to bowel movements.

Serious risks include systemic lidocaine toxicity, which can manifest as dizziness, seizures, cardiac arrhythmias, or methemoglobinemia, especially if large amounts are applied or if the mucosa is compromised. Allergic reactions such as rash, urticaria, or angioedema are also possible and require immediate medical attention.

Individuals with a known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid this product. It is also contraindicated in patients with severe mucosal ulceration, extensive skin breakdown in the rectal area, or those taking medications that significantly increase lidocaine plasma levels without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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