Product image of Lidocaine Aguettant (Lidocaine Hydrochloride) supplied by GNH India

Lidocaine Aguettant

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocaine Aguettant (Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Lidocaine Aguettant, is a local anesthetic presented as a sterile solution for endotracheopulmonary use. Manufactured under EU standards, it provides temporary loss of sensation in the airway and pulmonary structures during diagnostic or therapeutic procedures requiring localized anesthesia of the trachea, bronchi, or lung tissue.

GNH India supplies Lidocaine Aguettant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide. The company ensures quality assurance, regulatory compliance, and reliable cold‑chain logistics where required.

Manufacturer / TM Owner

Laboratoire Aguettant

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Indications & Clinical Uses

Lidocaine Aguettant is used to provide local anesthesia in the endotracheopulmonary tract.

  • Bronchoscopy: facilitates patient comfort and reduces cough reflex during airway examination.
  • Tracheal intubation: provides topical anesthesia to the tracheal mucosa to ease tube placement.
  • Pulmonary surgery: offers localized numbness of lung tissue during minimally invasive procedures.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of action potentials. By inhibiting sodium influx, it stabilizes the neuronal membrane and halts nerve impulse transmission, resulting in reversible loss of sensation in the targeted area.

Side Effects

Adverse reactions to Lidocaine Aguettant are generally related to its local anesthetic properties and systemic absorption.

Common Side Effects

  • Mild burning sensation at the application site
  • Transient numbness of the treated area
  • Light‑headed dizziness
  • Nausea

Serious or Rare Side Effects

  • Cardiac arrhythmias, including ventricular tachycardia
  • Seizures due to central nervous system toxicity
  • Severe allergic reaction (anaphylaxis)
  • Methemoglobinemia, a rare blood disorder

Precautions & Warnings

When using Lidocaine Aguettant, clinicians should observe several precautions to minimize risks.

  • Patient assessment: evaluate for known hypersensitivity to amide‑type local anesthetics.
  • Cardiac history: avoid in patients with significant conduction disorders or arrhythmias.
  • Dosage limit: adhere to recommended maximum dose to prevent systemic toxicity.
  • Concomitant CNS depressants: use caution when combined with other agents that lower seizure threshold.
  • Pregnancy and lactation: consider risk‑benefit ratio; use only if clearly needed.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Lidocaine Aguettant may interact with other medicines that affect cardiac conduction or central nervous system activity.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): additive cardiotoxicity.
  • Beta‑blockers: may enhance bradycardia.
  • CYP3A4 inhibitors (e.g., ketoconazole): increase lidocaine plasma levels.

Moderate Interactions (Monitor Closely)

  • Opioids: may increase sedation and respiratory depression.
  • Diuretics: may reduce plasma protein binding, raising free lidocaine.
  • Local anesthetic mixtures: risk of cumulative toxicity.

Frequently Asked Questions

Lidocaine Aguettant is a sterile solution of lidocaine hydrochloride that provides local anesthesia for endotracheopulmonary procedures. It is commonly employed during bronchoscopy, tracheal intubation, and minimally invasive pulmonary surgeries to numb the airway and lung tissue, improving patient comfort and procedural conditions.

Lidocaine works by blocking voltage‑gated sodium channels on nerve membranes, which prevents the influx of sodium ions needed for depolarisation. This inhibition stops the generation and propagation of action potentials, resulting in a reversible loss of sensation in the area where the drug is applied.

The dose of Lidocaine Aguettant is determined by the prescribing clinician based on the specific procedure, patient weight, and clinical context. Healthcare professionals calculate the amount needed to achieve adequate local anesthesia while staying within established safety limits for lidocaine exposure.

Safety data for Lidocaine Aguettant in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any potential risk to the fetus or infant. Clinicians are advised to assess each case individually and consider alternative options when possible.

To order Lidocaine Aguettant, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Lidocaine is an amide‑type local anesthetic with a rapid onset and moderate duration, making it suitable for short‑ to medium‑length airway procedures. Compared with agents such as bupivacaine, lidocaine has a shorter half‑life and lower cardiotoxic potential, but may require repeat dosing for longer surgeries.

Lidocaine Aguettant should be stored at room temperature, below 25 °C, in its original packaging. Protect the solution from direct light and moisture. Ensure that the container is sealed when not in use and that any unused portion is discarded according to local regulations after the labeled expiry date.

The product is administered by a qualified healthcare professional via endotracheopulmonary routes, typically as a topical spray or instillation onto the mucosal surfaces of the airway. The exact technique depends on the procedure, and the drug should be applied only to the intended area to achieve localized anesthesia.

Serious risks include systemic toxicity leading to cardiac arrhythmias, seizures, severe allergic reactions (anaphylaxis), and rare cases of methemoglobinemia. Early signs of toxicity such as dizziness, tinnitus, or altered mental status should prompt immediate medical evaluation and supportive care.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid the product. It is also contraindicated in individuals with significant cardiac conduction disorders, severe liver dysfunction, or those taking medications that markedly increase lidocaine plasma levels without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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