Product image of Lidocaine Aguettant (Lidocaine Hydrochloride) supplied by GNH India

Lidocaine Aguettant

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocaine Aguettant (Lidocaine Hydrochloride)

Lidocaine Hydrochloride, the active ingredient in Lidocaine Aguettant, is a local anesthetic presented as a sterile solution for infiltration, intradermal and intravenous use. It provides temporary loss of sensation for minor surgical or diagnostic procedures and can be used to manage certain cardiac arrhythmias.
GNH India supplies Lidocaine Aguettant as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Aguettant

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Indications & Clinical Uses

Lidocaine Aguettant acts on peripheral nerve sodium channels to produce reversible loss of sensation in several clinical settings.

  • Minor surgical or diagnostic procedures: provides infiltration anesthesia for temporary numbness of the targeted tissue.
  • Intradermal procedures: enables skin testing or minor dermatologic interventions with rapid onset.
  • Ventricular arrhythmias: administered intravenously to suppress ectopic ventricular activity in cardiac emergencies.

How It Works

  • Lidocaine Hydrochloride blocks voltage‑gated sodium channels in neuronal membranes, preventing the initiation and propagation of action potentials. By stabilizing the neuronal membrane, it interrupts nerve impulse conduction, resulting in reversible loss of sensation in the area of administration and, when given intravenously, reduces abnormal cardiac excitability.

Side Effects

Lidocaine Aguettant may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Burning or stinging at the injection site
  • Dizziness or light‑headedness
  • Nausea or mild vomiting
  • Metallic taste in the mouth
  • Transient hypotension
  • Headache

Serious or Rare Side Effects

  • Central nervous system toxicity (e.g., seizures, confusion)
  • Cardiac toxicity (e.g., arrhythmias, cardiac arrest)
  • Severe allergic reactions (e.g., anaphylaxis, rash)
  • Methemoglobinemia
  • Respiratory depression
  • Persistent hypotension requiring intervention

Precautions & Warnings

Before using Lidocaine Aguettant, clinicians should consider several safety measures.

  • Allergy assessment: verify no known hypersensitivity to amide‑type local anesthetics.
  • Cardiac monitoring: use caution in patients with conduction disorders or severe heart disease.
  • Dose calculation: ensure total administered dose does not exceed recommended maximums.
  • Concomitant CNS depressants: monitor for additive sedative effects.
  • Pregnancy and lactation: use only if the potential benefit justifies the potential risk.
  • Store at ambient temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Lidocaine Aguettant can interact with other medications, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Class I antiarrhythmic agents (e.g., quinidine, procainamide): additive cardiotoxicity.
  • Other amide‑type local anesthetics: risk of cumulative systemic toxicity.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): increase plasma lidocaine concentrations.

Moderate Interactions (Monitor Closely)

  • Beta‑adrenergic blockers: may enhance bradycardia.
  • Diuretics (e.g., furosemide): can reduce plasma protein binding, raising free drug levels.
  • General anesthetics (e.g., propofol, volatile agents): additive central nervous system depression.

Frequently Asked Questions

Lidocaine Aguettant is a sterile solution of lidocaine hydrochloride used to provide local anesthesia for minor surgical or diagnostic procedures, to numb skin for intradermal testing, and, when given intravenously, to treat certain ventricular arrhythmias by suppressing abnormal heart rhythms.

Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the rapid influx of sodium ions that initiates an action potential. This stabilizes the nerve membrane, halting impulse conduction and producing a reversible loss of sensation in the treated area.

The appropriate dose of Lidocaine Aguettant is determined by the prescribing clinician based on the specific procedure, patient weight, and clinical context. Dosing recommendations are provided in the product labeling and must be individualized for each patient.

Safety data for Lidocaine Aguettant in pregnancy and lactation are limited. It should be used only when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and any required import documentation.

Lidocaine has a rapid onset and moderate duration of action, making it suitable for short procedures. Compared with longer‑acting agents such as bupivacaine, lidocaine provides quicker recovery of sensation but may require repeat dosing for prolonged surgeries. Its safety profile is well‑established, and it is often preferred when a fast, controllable block is needed.

Store the sterile solution at ambient temperature, preferably below 25 °C, in its original packaging. Protect it from direct sunlight, moisture, and extreme temperature fluctuations. Do not freeze the product, and inspect the vial for any particulate matter or discoloration before use.

Lidocaine Aguettant is administered by infiltration, intradermal injection, or intravenous infusion, depending on the clinical indication. The injection technique follows standard aseptic procedures, and the volume injected is calculated based on the desired anesthetic effect and patient-specific factors.

Serious risks include central nervous system toxicity (seizures, confusion), cardiac toxicity (arrhythmias, cardiac arrest), severe allergic reactions such as anaphylaxis, methemoglobinemia, and profound hypotension. Prompt recognition and supportive management are essential if these events occur.

Patients with known hypersensitivity to lidocaine or other amide‑type local anesthetics, those with severe heart block, uncontrolled epilepsy, or significant hepatic impairment should avoid using Lidocaine Aguettant unless a specialist determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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