Product image of Lidocaine Egis (Lidocaine) supplied by GNH India

Lidocaine Egis

Active Ingredient:
Lidocaine
Origin:
EU

Lidocaine Egis (Lidocaine)

Lidocaine, the active ingredient in Lidocaine Egis, is a local anesthetic presented as a topical preparation for cutaneous use. It provides temporary numbing of the skin and mucous membranes, facilitating pain relief during minor procedures and minor skin irritations in adults and children.

GNH India supplies Lidocaine Egis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation to support global distribution, ensuring product integrity throughout the supply chain.

Manufacturer / TM Owner

Egis Pharmaceuticals Plc

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Indications & Clinical Uses

Lidocaine is a local anesthetic used to block nerve conduction in the skin.

  • Skin surface procedures: provides temporary numbness to facilitate minor surgical or diagnostic interventions.
  • Minor burns or abrasions: reduces pain during dressing changes.
  • Venipuncture or cannulation: eases discomfort from needle insertion.
  • Insect bite relief: alleviates itching and pain from minor insect stings.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the influx of sodium ions required for depolarisation. This inhibition stops the initiation and propagation of nerve impulses, resulting in reversible loss of sensation in the area where the drug is applied.

Side Effects

Lidocaine may cause a range of adverse reactions, from mild local irritation to rare systemic toxicity.

Common Side Effects

  • Localized skin irritation: mild redness at the application site.
  • Burning or stinging sensation: transient discomfort upon application.
  • Pruritus: itching of the treated area.
  • Edema: slight swelling of the skin.

Serious or Rare Side Effects

  • Systemic toxicity: dizziness, tinnitus, or seizures if absorbed in large amounts.
  • Cardiac effects: arrhythmias or hypotension in cases of overdose.
  • Severe allergic reaction: anaphylaxis or widespread rash.

Precautions & Warnings

Before using Lidocaine Egis, consider the following safety measures.

  • Allergy assessment: confirm the patient has no known hypersensitivity to lidocaine or related anesthetics.
  • Application area: limit use to intact skin and avoid large surface areas to reduce systemic absorption.
  • Mucous membranes: do not apply to eyes, inside the nose, or other mucosal surfaces unless specifically indicated.
  • Monitoring: observe for signs of systemic toxicity such as CNS or cardiac symptoms during extensive use.
  • Pregnancy and lactation: use only if the potential benefit justifies the potential risk; consult a healthcare professional.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lidocaine can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Other local anesthetics: additive toxicity may increase risk of systemic effects.
  • Class I antiarrhythmics (e.g., quinidine, procainamide): combined use can heighten cardiac conduction disturbances.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may raise systemic lidocaine levels.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask tachycardia that signals lidocaine toxicity.
  • Diuretics: can elevate plasma concentrations of lidocaine.
  • Alcohol: may potentiate central nervous system depression when used together.

Frequently Asked Questions

Lidocaine Egis is a topical formulation of lidocaine intended to provide local anesthesia of the skin. It is commonly applied to numb the surface for minor surgical or diagnostic procedures, to relieve pain from small burns, abrasions, insect bites, and to ease discomfort during venipuncture or cannulation.

Lidocaine works by blocking voltage‑gated sodium channels on nerve cells. By preventing sodium influx, it stops the generation and propagation of action potentials, which temporarily halts the transmission of pain signals from the treated area to the brain.

The appropriate amount of Lidocaine Egis is determined by the prescribing healthcare professional based on the size of the area to be treated, the patient’s age, and the specific procedure. Patients should follow the exact instructions provided by their clinician and not exceed the recommended application.

Safety data for topical lidocaine in pregnancy and lactation are limited. It should only be used when the potential benefit outweighs any possible risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Lidocaine is a widely used amide‑type local anesthetic offering rapid onset and moderate duration of action. Compared with benzocaine, another topical anesthetic, lidocaine generally provides deeper penetration and a longer numbness period, while having a well‑characterised safety profile and lower risk of methemoglobinemia.

Store Lidocaine Egis at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and ensure it is out of reach of children. Do not freeze or expose the product to extreme temperatures.

Lidocaine Egis is applied directly to the skin surface. The clinician cleans the area, spreads a thin layer of the preparation over the target region, and allows it to absorb for the recommended time before proceeding with the procedure. It should not be ingested or injected.

The most serious adverse events include systemic toxicity leading to central nervous system symptoms such as seizures, cardiac arrhythmias or hypotension, and severe allergic reactions like anaphylaxis. These risks are rare but require immediate medical attention if signs such as dizziness, irregular heartbeat, or widespread rash appear.

Individuals with a known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid using the product. It is also contraindicated in patients with severe heart block, certain cardiac conduction disorders, or those taking medications that may significantly increase lidocaine plasma levels without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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