Product image of Lidocaína 5% Braun (Lidocaine Hydrochloride) supplied by GNH India

Lidocaína 5% Braun

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocaína 5% Braun (Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Lidocaína 5% Braun, is a local anesthetic presented as a 5% injectable solution for epidural, intramuscular, and intravenous use. It provides local anesthesia and analgesia in surgical and procedural settings.

GNH India supplies Lidocaína 5% Braun as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B. Braun Medical Lda.

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Indications & Clinical Uses

Lidocaine is used to achieve local anesthesia and analgesia in various clinical settings.

  • Surgical procedures: provides regional or local anesthesia to facilitate surgery
  • Labor and delivery: used for epidural analgesia to reduce pain during childbirth
  • Diagnostic procedures: numbs tissue for minor surgeries or catheter insertions

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, stabilizing the neuronal membrane and preventing the initiation and propagation of action potentials. By inhibiting sodium influx, it interrupts nerve impulse transmission, resulting in reversible loss of sensation in the targeted area without affecting surrounding tissues.

Side Effects

Adverse reactions may range from mild, transient events to rare but serious complications.

Common Side Effects

  • Transient burning or stinging at the injection site
  • Mild dizziness or light‑headedness
  • Nausea or vomiting
  • Metallic taste in the mouth
  • Localized swelling or erythema
  • Headache

Serious or Rare Side Effects

  • Seizures or convulsions
  • Cardiac arrhythmias, including ventricular tachycardia
  • Severe hypotension or cardiovascular collapse
  • Allergic reactions such as anaphylaxis
  • Methemoglobinemia
  • Persistent neurologic deficits

Precautions & Warnings

Before administration, clinicians should consider several safety measures.

  • Allergy assessment: confirm no known hypersensitivity to amide‑type local anesthetics
  • Cardiovascular status: avoid in patients with severe heart block or conduction disorders
  • Neurological conditions: use cautiously in patients with epilepsy or seizure disorders
  • Dosage limits: adhere to recommended maximum dose to prevent systemic toxicity
  • Concurrent CNS depressants: monitor for additive sedative effects
  • Store at room temperature: keep in original container, protect from light and moisture

Avoid Interactions

Lidocaine may interact with other medications, requiring careful management.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may increase lidocaine plasma levels and toxicity risk
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): can reduce lidocaine metabolism leading to accumulation

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may enhance cardiac depressant effects of lidocaine
  • General anesthetics (e.g., propofol, volatile agents): additive central nervous system depression
  • Diuretics (e.g., furosemide): may alter plasma protein binding and increase free drug concentration
  • Other local anesthetics: concurrent use raises cumulative toxicity potential

Frequently Asked Questions

Lidocaína 5% Braun is a lidocaine‑based injectable solution used to provide local or regional anesthesia and analgesia. It is commonly employed during surgical procedures, obstetric epidural analgesia, and minor diagnostic or therapeutic interventions where temporary loss of sensation is required.

Lidocaine blocks voltage‑gated sodium channels on nerve membranes, preventing the rapid influx of sodium ions that initiates an action potential. This inhibition stops nerve impulse propagation, resulting in a reversible loss of sensation in the area where the drug is administered.

The specific dose of Lidocaína 5% Braun is determined by the prescribing clinician based on the procedure, patient weight, age, and clinical condition. Healthcare professionals calculate the appropriate volume to stay within recommended maximum limits and to achieve the desired anesthetic effect.

Safety data for lidocaine use in pregnancy and lactation are limited. It is generally classified as Category B in many regions, indicating that animal studies have not shown risk but human data are insufficient. Use only when the potential benefit justifies any potential risk to the fetus or infant, and always under medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

The primary alternative to lidocaine is bupivacaine, which has a longer duration of action but a higher risk of cardiotoxicity at comparable doses. Lidocaine offers a faster onset and a shorter, more controllable duration, making it preferable for procedures requiring rapid recovery of sensation. Choice depends on the clinical need for duration versus safety profile.

Lidocaína 5% Braun should be stored at room temperature, below 25 °C, in its original sealed container. Protect the product from direct sunlight, moisture, and extreme temperature fluctuations. Do not freeze. Inspect the solution before use for any particulate matter or discoloration and discard if integrity is compromised.

The product is administered by a qualified healthcare professional via epidural, intramuscular, or intravenous injection, depending on the intended clinical use. The injection site is prepared aseptically, and the volume injected is calculated to stay within safe dosage limits. Continuous monitoring is recommended during and after administration.

Serious risks include central nervous system toxicity (seizures, loss of consciousness), cardiovascular complications (arrhythmias, severe hypotension, cardiac arrest), and allergic reactions such as anaphylaxis. These events are rare but require immediate medical intervention. Monitoring of vital signs and plasma drug levels is essential when high doses are used.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid this product. It is also contraindicated in individuals with severe heart block, uncontrolled epilepsy, or significant hepatic impairment that could impair drug metabolism. Clinicians must assess each patient’s medical history before administration.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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