Product image of Lidocaína B. Braun (Lidocaine Hydrochloride) supplied by GNH India

Lidocaína B. Braun

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocaína B. Braun (Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Lidocaína B. Braun, is a local anesthetic presented as a sterile solution for epidural, infiltration and intradermal use. It provides reversible nerve block to facilitate minor surgical procedures, obstetric analgesia and diagnostic skin testing in adult patients.

GNH India supplies Lidocaína B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. The company adheres to stringent quality standards and provides reliable logistics for global healthcare institutions. Its portfolio includes a range of injectable medicines for perioperative care.

Manufacturer / TM Owner

B.Braun Medical, S.A.

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Indications & Clinical Uses

Lidocaína B. Braun is used to provide local anesthesia in several clinical settings.

  • Minor surgical procedures: provides surface or deep anesthesia to facilitate incision and suturing.
  • Epidural analgesia: delivers analgesia for labor, postoperative pain or chronic back pain.
  • Infiltration anesthesia: numbs tissue surrounding a surgical site for dental, orthopedic or dermatologic interventions.
  • Intradermal anesthesia: enables painless skin testing and minor dermatologic procedures.

How It Works

  • Lidocaine acts by reversibly binding to voltage‑gated sodium channels on neuronal membranes, stabilizing the inactive state of the channel. This blockade prevents the rapid influx of sodium ions required for depolarization, thereby inhibiting initiation and propagation of nerve impulses. The effect is concentration‑dependent and occurs rapidly after administration, producing a temporary loss of sensation in the targeted area.

Side Effects

Lidocaine may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Tingling or numbness at the injection site.
  • Metallic taste or mild mouth irritation.
  • Dizziness or light‑headed feeling.
  • Nausea or mild vomiting.

Serious or Rare Side Effects

  • Seizures or convulsions, especially with high plasma levels.
  • Cardiac arrhythmias, including ventricular tachycardia.
  • Severe hypotension or cardiovascular collapse.
  • Allergic reactions such as rash, urticaria or anaphylaxis.

Precautions & Warnings

When using Lidocaína B. Braun, clinicians should observe several safety measures to minimize risk.

  • Assess patient allergy: verify no known hypersensitivity to amide‑type local anesthetics.
  • Use lowest effective concentration: select the minimal dose required for the intended procedure.
  • Monitor cardiovascular status: observe heart rate and blood pressure during and after administration.
  • Avoid intravascular injection: aspirate before injecting to prevent systemic toxicity.
  • Adjust dose in hepatic impairment: reduce total dose in patients with liver dysfunction.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Lidocaine can interact with other medicines, altering its efficacy or increasing toxicity.

Major Interactions (Avoid)

  • Class I antiarrhythmic agents (e.g., quinidine, procainamide): may raise lidocaine plasma concentrations and risk toxicity.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): can significantly increase systemic exposure.

Moderate Interactions (Monitor Closely)

  • Other amide local anesthetics: cumulative effect may enhance neuro‑ or cardiotoxicity.
  • CYP1A2 inducers (e.g., carbamazepine, rifampin): may reduce lidocaine effectiveness.
  • Diuretics such as furosemide: can increase free lidocaine levels by altering protein binding.
  • General anesthetics (e.g., propofol, inhalational agents): additive central nervous system depression.

Frequently Asked Questions

Lidocaína B. Braun is a prescription‑only local anesthetic used to produce temporary loss of sensation in targeted tissues. It is employed for minor surgical procedures, epidural analgesia during labor or postoperative pain management, infiltration anesthesia for dental, orthopedic or dermatologic interventions, and intradermal anesthesia for skin testing.

Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, stabilising them in an inactive state. By preventing sodium influx, the drug stops the depolarisation necessary for nerve impulse generation and propagation, resulting in a reversible loss of sensation in the area where it is administered.

The appropriate dose of Lidocaína B. Braun is determined by the prescribing clinician based on the specific procedure, the site of administration, patient age, weight, and overall health status. No standard dosing is provided here; the prescriber tailors the amount to achieve effective anesthesia while minimising toxicity.

Safety data for lidocaine in pregnancy and lactation are limited. Use is generally reserved for situations where the benefit outweighs potential risk, and the decision should be made by a qualified healthcare professional. Breastfeeding mothers should consult their physician, as lidocaine can be excreted in small amounts in milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Lidocaine has a rapid onset of action (1–3 minutes) and a moderate duration (30–120 minutes), whereas bupivacaine has a slower onset but a longer duration (up to several hours). Lidocaine is often chosen for procedures requiring quick recovery, while bupivacaine is preferred for prolonged analgesia. Both share similar mechanisms but differ in potency and toxicity profiles.

Lidocaína B. Braun should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from direct sunlight, moisture and extreme temperature fluctuations. Do not freeze the solution, and keep it out of reach of children.

The product is supplied as a sterile solution for injection and is administered by a qualified healthcare professional via epidural, infiltration or intradermal routes. The clinician selects the appropriate needle size, injects the solution slowly, and monitors the patient for any immediate adverse reactions.

Serious risks include central nervous system toxicity such as seizures, and cardiovascular toxicity manifesting as arrhythmias, severe hypotension or cardiac arrest. These events are more likely with high plasma concentrations, accidental intravascular injection, or when combined with interacting medications.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid this product. Caution is also advised for individuals with severe hepatic impairment, significant cardiac conduction disorders, or those taking medications that markedly increase lidocaine plasma levels.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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