Product image of Lidocaïne Accord (Lidocaine Hydrochloride) supplied by GNH India

Lidocaïne Accord

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocaïne Accord (Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Lidocaïne Accord, is a local anesthetic (amide type) presented as a sterile solution for epidural, intramuscular and intravenous use. It provides reversible loss of sensation for minor surgical procedures, labor analgesia and regional anesthesia.
GNH India supplies Lidocaïne Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Accord Healthcare France Sas

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Indications & Clinical Uses

Lidocaïne Accord is a local anesthetic used in various procedural and pain‑management pathways.

  • Minor surgical or diagnostic procedures: provides rapid, reversible loss of sensation in the targeted tissue.
  • Epidural analgesia during labor or surgery: delivers continuous pain relief while preserving motor function.
  • Intravenous regional anesthesia (Bier block): produces rapid, localized anesthesia for limb surgeries.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, stabilising the neuronal membrane and preventing the initiation and propagation of action potentials. This reversible inhibition halts nerve impulse transmission, resulting in loss of sensation in the area where the drug is applied.

Side Effects

Lidocaine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Transient burning or stinging at the injection site
  • Mild hypotension
  • Dizziness or light‑headedness
  • Nausea or vomiting

Serious or Rare Side Effects

  • Allergic reactions including anaphylaxis
  • Cardiac arrhythmias or conduction disturbances
  • Methemoglobinemia
  • Central nervous system toxicity such as seizures

Precautions & Warnings

Careful assessment and monitoring are required when using Lidocaïne Accord.

  • Allergy assessment: verify no known hypersensitivity to amide‑type local anesthetics.
  • Cardiovascular status: monitor patients with heart block, conduction disorders or severe cardiac disease.
  • Dosage limits: avoid exceeding recommended total dose for the selected route of administration.
  • Concurrent CNS depressants: use caution when combined with other agents that depress the central nervous system.
  • Pregnancy and lactation: evaluate risk‑benefit; data are limited.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Lidocaine can interact with several drug classes, requiring vigilance.

Major Interactions (Avoid)

  • Class I antiarrhythmic agents (e.g., quinidine, procainamide): may enhance cardiotoxicity.
  • Beta‑blockers: increase risk of bradycardia and hypotension.
  • General anesthetics (e.g., propofol, volatile agents): additive central nervous system depression.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase bleeding risk with regional techniques.
  • Monoamine oxidase inhibitors (MAOIs): potential for prolonged anesthetic effect.
  • Calcium channel blockers: may potentiate hypotensive effects.

Frequently Asked Questions

Lidocaïne Accord is a lidocaine‑based local anesthetic used to provide reversible loss of sensation during minor surgical or diagnostic procedures, to deliver epidural analgesia for labor or surgery, and to perform intravenous regional anesthesia (Bier block) for limb surgeries.

Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, stabilising the membrane and preventing the initiation and propagation of nerve impulses. This reversible blockade stops pain signals from reaching the brain, producing localized numbness.

The appropriate dose of Lidocaïne Accord is determined by the prescribing clinician based on the route of administration, patient weight, procedure type and safety limits. Exact dosing regimens are not disclosed here and must follow the prescriber’s order.

Safety data for lidocaine during pregnancy and lactation are limited. Use is generally reserved for situations where the benefit outweighs potential risk, and the decision should be made by the treating physician after evaluating maternal and fetal considerations.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Both lidocaine and bupivacaine are amide‑type local anesthetics, but lidocaine has a faster onset and shorter duration of action, making it suitable for short procedures. Bupivacaine provides longer lasting analgesia but carries a higher risk of cardiotoxicity at equivalent doses.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging. Protect it from direct sunlight, moisture and extreme temperature fluctuations. Ensure the container is sealed when not in use to maintain sterility.

Lidocaïne Accord is administered by a qualified healthcare professional via epidural, intramuscular or intravenous routes, depending on the clinical indication. The drug is injected as a sterile solution, and dosage is adjusted according to the specific procedure and patient factors.

Serious risks include allergic reactions such as anaphylaxis, cardiac arrhythmias or conduction disturbances, methemoglobinemia, and central nervous system toxicity leading to seizures. Immediate medical attention is required if any of these events occur.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, those with severe cardiac conduction disorders, and individuals taking certain Class I antiarrhythmic drugs should avoid using Lidocaïne Accord unless a specialist determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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