Product image of Lidocaïne Hcl Cf (Lidocaine Hydrochloride) supplied by GNH India

Lidocaïne Hcl Cf

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocaïne Hcl Cf (Lidocaine Hydrochloride)

Lidocaine Hydrochloride, the active ingredient in Lidocaïne Hcl Cf, is a local anesthetic presented as a sterile solution for intravenous use. It provides reversible nerve block for minor surgical procedures, ventricular arrhythmias, and diagnostic nerve blocks in adult patients.

GNH India supplies Lidocaïne Hcl Cf as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Centrafarm B.V.

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Indications & Clinical Uses

Lidocaine Hydrochloride is employed in clinical settings that require rapid, reversible nerve blockade.

  • Minor surgical procedures: provides local anesthesia to reduce pain during the operation.
  • Ventricular arrhythmias: stabilizes cardiac rhythm when administered intravenously.
  • Diagnostic nerve blocks: temporarily blocks nerve conduction for diagnostic testing.

How It Works

  • Lidocaine Hydrochloride acts by reversibly binding to voltage‑gated sodium channels on neuronal membranes, preventing the influx of sodium ions during depolarisation. This blockade inhibits the generation and propagation of nerve impulses, resulting in loss of sensation in the targeted area and, when given intravenously, can suppress abnormal cardiac electrical activity.

Side Effects

Lidocaine Hydrochloride may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Tingling or numbness at the injection site
  • Mild dizziness or light‑headedness
  • Nausea or vomiting
  • Metallic taste in the mouth
  • Transient visual disturbances
  • Headache

Serious or Rare Side Effects

  • Severe hypotension or cardiovascular collapse
  • Life‑threatening cardiac arrhythmias
  • Anaphylactic or severe allergic reaction
  • Methemoglobinemia
  • Central nervous system toxicity (e.g., seizures)
  • Respiratory depression

Precautions & Warnings

Before using Lidocaine Hydrochloride, clinicians should consider several safety measures.

  • Allergy assessment: avoid use in patients with known lidocaine hypersensitivity.
  • Cardiac monitoring: observe patients with pre‑existing heart disease.
  • Dose adjustment: consider reduced doses in hepatic impairment.
  • Concurrent CNS depressants: use with caution as additive effects may occur.
  • Pregnancy and lactation: safety not established; weigh benefits against potential risks.
  • Store at controlled room temperature (15‑30 °C): keep in original container, protect from light and moisture.

Avoid Interactions

Lidocaine Hydrochloride can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may cause severe cardiotoxicity.
  • Beta‑blockers (e.g., propranolol): can enhance cardiac depression.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): increase lidocaine plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Central nervous system depressants (e.g., benzodiazepines, opioids): additive sedation.
  • Diuretics (e.g., furosemide): may raise risk of arrhythmias.
  • Concurrent local anesthetic mixtures: monitor total dose to avoid systemic toxicity.

Frequently Asked Questions

Lidocaïne Hcl Cf contains lidocaine hydrochloride, a local anesthetic used to provide rapid, reversible nerve block for minor surgical procedures, to manage ventricular arrhythmias when given intravenously, and to perform diagnostic nerve blocks that help identify the source of pain.

Lidocaine blocks voltage‑gated sodium channels on nerve and cardiac cells, preventing sodium influx during depolarisation. This stops the propagation of electrical impulses, producing loss of sensation in the targeted area and, in the heart, stabilising abnormal rhythm.

The specific dose of Lidocaïne Hcl Cf is determined by the prescribing clinician based on the indication, patient weight, age, and clinical condition. Healthcare professionals adjust the amount to achieve the desired anesthetic or anti‑arrhythmic effect while monitoring safety.

Safety data for lidocaine hydrochloride in pregnancy and lactation are limited. It is classified as pregnancy category unknown, so clinicians must weigh potential benefits against possible risks and consider alternative therapies when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs) and required import documentation.

Lidocaine has a rapid onset and moderate duration, making it suitable for short procedures and emergency cardiac use. Compared with bupivacaine, which lasts longer but has a slower onset, lidocaine offers quicker pain relief but may require repeat dosing for prolonged surgeries.

Lidocaïne Hcl Cf should be stored at controlled room temperature (15‑30 °C) in its original sealed container, protected from light and moisture. Do not freeze the solution, and keep it out of direct sunlight to maintain stability.

The product is supplied as a sterile solution for intravenous injection. Administration is performed by a qualified healthcare professional, who injects the prescribed volume directly into a vein, often using an infusion pump or syringe, depending on the clinical scenario.

Serious adverse events include severe hypotension, life‑threatening cardiac arrhythmias, anaphylactic reactions, methemoglobinemia, and central nervous system toxicity such as seizures. Prompt recognition and supportive measures are essential if these occur.

Patients with known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid this product. It is also contraindicated in individuals with severe heart block, uncontrolled heart failure, or those taking certain antiarrhythmic drugs that may precipitate toxicity.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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