Product image of Lidocaine Hydrochloride B. Braun Melsungen (Lidocaine Hydrochloride Monohydrate) supplied by GNH India

Lidocaine Hydrochloride B. Braun Melsungen

Active Ingredient:
Lidocaine Hydrochloride Monohydrate
Origin:
EU

Lidocaine Hydrochloride B. Braun Melsungen (Lidocaine Hydrochloride Monohydrate)

Lidocaine, the active ingredient in Lidocaine Hydrochloride B. Braun Melsungen, is a local anesthetic presented as a sterile solution for epidural, infiltration and intradermal use. It provides rapid, reversible loss of sensation in targeted tissues and is employed in a variety of minor surgical and diagnostic procedures.

GNH India supplies Lidocaine Hydrochloride B. Braun Melsungen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Lidocaine is a local anesthetic used to block nerve conduction in specific procedural settings.

  • Epidural anesthesia: provides localized numbness for epidural procedures and obstetric analgesia.
  • Infiltration anesthesia: numbs tissue for minor surgical, dental or diagnostic interventions.
  • Intradermal anesthesia: used for superficial skin anesthesia in dermatologic or cosmetic procedures.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the rapid influx of sodium ions required for depolarization. This inhibition halts the initiation and propagation of nerve impulses, resulting in reversible loss of sensation in the area where the drug is administered.

Side Effects

Lidocaine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Burning or tingling at the injection site.
  • Mild dizziness or light‑headedness.
  • Nausea or a metallic taste.
  • Transient hypotension.
  • Localized swelling or erythema.

Serious or Rare Side Effects

  • Seizures or convulsions.
  • Cardiac arrhythmias, including ventricular tachycardia.
  • Severe hypotension or cardiovascular collapse.
  • Methemoglobinemia.
  • Anaphylactic or severe allergic reactions.

Precautions & Warnings

When using Lidocaine Hydrochloride, several safety measures should be observed.

  • Allergy assessment: verify no known hypersensitivity to amide‑type local anesthetics.
  • Cardiovascular monitoring: observe for signs of arrhythmia or hypotension during and after administration.
  • Dosage calculation: ensure dose is appropriate for patient weight, site, and intended use.
  • Use in compromised patients: exercise caution in individuals with liver disease or pre‑existing cardiac conduction disorders.
  • Concurrent CNS depressants: avoid or closely monitor when combined with other central nervous system depressants.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Lidocaine can interact with other medicines, affecting its safety or efficacy.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may increase plasma lidocaine levels and risk toxicity.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): can raise lidocaine concentrations.
  • Beta‑blockers: may potentiate cardiac depression when used together.

Moderate Interactions (Monitor Closely)

  • Other local anesthetics: additive neuro‑ or cardiotoxic effects.
  • Diuretics (e.g., furosemide): may alter plasma protein binding, affecting free drug levels.
  • General anesthetics (e.g., propofol, volatile agents): may enhance central nervous system depression.

Frequently Asked Questions

Lidocaine Hydrochloride B. Braun Melsungen is a sterile local anesthetic solution used to provide temporary loss of sensation for epidural, infiltration and intradermal procedures. It is commonly employed in minor surgeries, obstetric analgesia, dental work and dermatologic interventions to ensure patient comfort.

Lidocaine works by blocking voltage‑gated sodium channels on nerve membranes, which prevents the rapid influx of sodium ions needed for depolarisation. This inhibition stops the generation and propagation of nerve impulses, resulting in a reversible loss of sensation in the area where the drug is administered.

The specific dose of lidocaine is determined by the prescribing clinician based on the procedure, patient weight, site of administration and safety considerations. Health‑care professionals calculate the appropriate volume and concentration to achieve effective anesthesia while staying within recommended maximum limits.

Safety data for lidocaine in pregnancy and lactation are limited, and the product does not have a definitive pregnancy category. Clinicians should weigh the potential benefits against any possible risks and use the lowest effective dose if treatment is deemed necessary.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Lidocaine is an amide‑type local anesthetic with a rapid onset (1–3 minutes) and intermediate duration (30–120 minutes), making it versatile for many procedures. Compared with shorter‑acting agents like procaine, lidocaine offers faster action and longer analgesia, while its safety profile is well‑established relative to longer‑acting agents such as bupivacaine.

Lidocaine Hydrochloride should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect the solution from direct light, moisture and extreme temperature fluctuations to maintain sterility and potency.

The solution is administered by a qualified health‑care professional via epidural catheter, direct infiltration into tissue, or intradermal injection, depending on the clinical indication. Proper aseptic technique and accurate dosing are essential to achieve effective anesthesia and minimise adverse effects.

Serious risks include central nervous system toxicity (seizures, loss of consciousness), cardiovascular toxicity (arrhythmias, severe hypotension, cardiac arrest), methemoglobinemia and severe allergic reactions such as anaphylaxis. Prompt recognition and supportive management are critical if these events occur.

Patients with a known hypersensitivity to amide‑type local anesthetics, severe liver disease, certain cardiac conduction disorders, or those taking medications that markedly increase lidocaine plasma levels should avoid its use unless a specialist determines that benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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