Product image of Lidocaine Hydrochloride Bp B. Braun Melsungen (Lidocaine Hydrochloride Monohydrate) supplied by GNH India

Lidocaine Hydrochloride Bp B. Braun Melsungen

Active Ingredient:
Lidocaine Hydrochloride Monohydrate
Origin:
EU

Lidocaine Hydrochloride Bp B. Braun Melsungen (Lidocaine Hydrochloride Monohydrate)

Lidocaine, the active ingredient in Lidocaine Hydrochloride Bp B. Braun Melsungen, is a local anesthetic presented as a sterile solution for epidural, intradermal, and intramuscular use. It provides reversible nerve block for minor surgical procedures, epidural analgesia, and skin anesthesia.
GNH India supplies Lidocaine Hydrochloride Bp B. Braun Melsungen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Lidocaine is a local anesthetic used across several procedural pathways to achieve temporary loss of sensation.

  • Minor surgical procedures: provides localized numbness to facilitate painless incision and manipulation.
  • Epidural analgesia: delivers segmental pain relief during labor or postoperative recovery.
  • Intradermal anesthesia: numbs skin for diagnostic testing or minor dermatologic interventions.
  • Dental procedures: anesthetizes oral tissues for extractions, restorations and other dental work.

How It Works

  • Lidocaine reversibly blocks voltage‑gated sodium channels on neuronal membranes, preventing the rapid influx of sodium ions required for depolarization. This inhibition halts the initiation and propagation of nerve impulses, resulting in a temporary loss of sensory perception in the targeted area without affecting surrounding tissues.

Side Effects

Lidocaine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Tingling or numbness at the injection site
  • Mild dizziness or light‑headedness
  • Nausea or metallic taste
  • Transient swelling or erythema at the site

Serious or Rare Side Effects

  • Cardiac arrhythmias, including ventricular tachycardia
  • Seizures or convulsions
  • Severe allergic reaction (anaphylaxis) with rash, bronchospasm, or hypotension
  • Methemoglobinemia leading to cyanosis and hypoxia

Precautions & Warnings

Before using Lidocaine, several safety considerations should be observed.

  • Assess patient allergy: verify no known hypersensitivity to amide‑type local anesthetics.
  • Monitor cardiac status: observe for arrhythmias, especially with high cumulative doses.
  • Use caution in hepatic impairment: reduced metabolism may increase systemic exposure.
  • Avoid in patients with severe conduction disorders unless benefits outweigh risks.
  • Store at below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Lidocaine can interact with other medicines, altering its safety profile.

Major Interactions (Avoid)

  • Class I antiarrhythmic agents (e.g., quinidine, procainamide): increase risk of lidocaine toxicity.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): raise plasma concentrations.
  • CYP1A2 inducers (e.g., carbamazepine, phenobarbital): may reduce therapeutic effect.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may potentiate cardiac depressant effects.
  • Concurrent use of other local anesthetics: cumulative toxicity risk.
  • Loop diuretics (e.g., furosemide): may alter protein binding and increase free drug levels.

Frequently Asked Questions

Lidocaine Hydrochloride Bp B. Braun Melsungen is a sterile injectable solution of the local anesthetic lidocaine. It is employed to produce temporary loss of sensation for minor surgical procedures, epidural analgesia during labor or surgery, and intradermal anesthesia for skin‑related interventions.

Lidocaine works by reversibly binding to voltage‑gated sodium channels on nerve membranes. This blocks sodium influx, preventing the rapid depolarization needed for nerve impulse generation and propagation, thereby producing a localized anesthetic effect without affecting surrounding tissues.

The specific dose of lidocaine is determined by the prescribing clinician based on the procedure, patient weight, site of administration, and overall health status. Healthcare professionals calculate the appropriate volume and concentration to achieve effective anesthesia while staying within safety limits.

Safety data for lidocaine during pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Lidocaine is an amide‑type local anesthetic with a rapid onset and moderate duration, often compared to bupivacaine, which has a slower onset but longer lasting effect. Clinicians may choose lidocaine for procedures requiring quick anesthesia and shorter recovery, whereas bupivacaine is preferred when prolonged analgesia is needed.

Lidocaine Hydrochloride Bp B. Braun Melsungen should be stored at temperatures below 25 °C, protected from direct sunlight, moisture and extreme temperature fluctuations. Keep the vial in its original packaging until use, and discard any solution that appears discolored or contains particles.

The product is administered by a qualified healthcare professional via injection. Routes include epidural, intradermal, or intramuscular injection, depending on the clinical indication. Proper aseptic technique and dosage calculation are essential to ensure effective anesthesia and minimize adverse effects.

Serious risks include cardiac arrhythmias, seizures, severe allergic reactions (anaphylaxis), and methemoglobinemia. These events are rare but can be life‑threatening, especially with high systemic concentrations or accidental intravascular injection. Immediate medical intervention is required if any of these symptoms occur.

Lidocaine should be avoided in individuals with known hypersensitivity to amide‑type local anesthetics, severe hepatic impairment, or significant cardiac conduction disorders unless the therapeutic benefit justifies the risk. Patients on interacting medications should be evaluated carefully by their prescriber.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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