Product image of Lidocaine Hydrochloride Bp Mercury Pharmaceuticals (Lidocaine Hydrochloride) supplied by GNH India

Lidocaine Hydrochloride Bp Mercury Pharmaceuticals

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidocaine Hydrochloride Bp Mercury Pharmaceuticals (Lidocaine Hydrochloride)

Lidocaine Hydrochloride, the active ingredient in Lidocaine Hydrochloride Bp Mercury Pharmaceuticals, is an amide-type local anesthetic presented as a sterile solution for intravenous use. It provides local anesthesia for minor surgical procedures and can be employed in the management of ventricular arrhythmias in appropriate clinical settings.

GNH India supplies Lidocaine Hydrochloride Bp Mercury Pharmaceuticals as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mercury Pharmaceuticals Ltd.

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Indications & Clinical Uses

Lidocaine Hydrochloride acts on nerve conduction and cardiac electrical activity, making it useful in several clinical contexts.

  • Minor surgical procedures: provides reversible loss of sensation to facilitate painless operation.
  • Ventricular arrhythmias: stabilises cardiac rhythm during acute episodes.
  • Regional nerve block procedures: enables analgesia for diagnostic or therapeutic interventions.

How It Works

  • Lidocaine Hydrochloride blocks voltage‑gated sodium channels on neuronal and cardiac membranes, preventing the rapid influx of sodium ions required for depolarisation. This inhibition halts the initiation and propagation of action potentials, resulting in loss of sensation in peripheral nerves and suppression of abnormal cardiac electrical activity.

Side Effects

Adverse reactions may occur following intravenous administration of lidocaine.

Common Side Effects

  • Tingling or numbness at the injection site
  • Mild hypotension
  • Metallic taste in the mouth
  • Dizziness or light‑headedness
  • Nausea or vomiting
  • Transient visual disturbances

Serious or Rare Side Effects

  • Seizures or convulsions
  • Cardiac arrest or severe arrhythmias
  • Severe allergic reaction (anaphylaxis)
  • Respiratory depression
  • Persistent hypotension requiring intervention
  • Methemoglobinemia

Precautions & Warnings

Lidocaine Hydrochloride requires careful patient assessment and monitoring.

  • Allergy assessment: avoid use in patients with known hypersensitivity to amide‑type local anesthetics.
  • Cardiac monitoring: observe for arrhythmias or conduction disturbances during IV administration.
  • Dose adjustment: consider reduced doses in patients with hepatic impairment.
  • Concurrent CNS depressants: use caution when combined with other agents that lower seizure threshold.
  • Pregnancy and lactation: safety not established; weigh benefits against potential risks.
  • Store below 25°C: keep in original container, protect from light and moisture.

Avoid Interactions

Lidocaine Hydrochloride can interact with several drug classes, influencing efficacy and safety.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): additive cardiotoxicity.
  • Beta‑adrenergic blockers: may potentiate bradycardia.
  • CYP3A4 inhibitors (e.g., ketoconazole): increase lidocaine plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Other local anesthetics: risk of cumulative systemic toxicity.
  • Diuretics (e.g., furosemide): may enhance hypotensive effect.
  • General anesthetics (e.g., propofol): monitor for additive CNS depression.

Frequently Asked Questions

Lidocaine Hydrochloride Bp is used as a local anesthetic to provide reversible loss of sensation during minor surgical procedures and as an anti‑arrhythmic agent for the acute management of ventricular arrhythmias. It works by blocking nerve conduction and stabilising cardiac electrical activity.

Lidocaine blocks voltage‑gated sodium channels on neuronal and cardiac cell membranes, preventing the rapid influx of sodium that initiates action potentials. This inhibition stops the propagation of nerve impulses, producing local anaesthesia, and suppresses abnormal cardiac electrical activity, helping to control arrhythmias.

The dosage of lidocaine Hydrochloride Bp is determined by the prescribing clinician based on the specific procedure, patient weight, age, and clinical condition. Healthcare professionals calculate the appropriate amount and administration rate to ensure safety and efficacy.

Safety data for lidocaine Hydrochloride Bp in pregnancy and lactation are limited, and the pregnancy category is listed as unknown. Clinicians should evaluate the potential benefits against possible risks before prescribing to pregnant or nursing patients.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lidocaine is an amide‑type local anesthetic with a rapid onset and moderate duration, making it suitable for short‑to‑moderate procedures. Compared with ester‑type agents, it generally has a lower risk of allergic reactions and is metabolised hepatically, allowing predictable clearance in most patients.

Lidocaine Hydrochloride Bp should be stored below 25 °C, in its original packaging, protected from light and moisture. Maintaining these conditions preserves the solution’s stability and potency throughout its shelf life.

The product is supplied as a sterile injectable solution for intravenous use. Administration is performed by a qualified healthcare professional, who injects the solution directly into a vein, typically using an infusion pump or controlled syringe to manage the rate and total dose.

Serious risks include seizures, severe cardiac arrhythmias or arrest, and anaphylactic reactions. These events are rare but require immediate medical intervention. Monitoring of cardiac and neurological status during and after administration helps mitigate these risks.

Patients with known hypersensitivity to amide‑type local anesthetics, those with severe hepatic impairment, or individuals taking interacting Class I antiarrhythmics or strong CYP3A4 inhibitors should avoid lidocaine Hydrochloride Bp unless a risk‑benefit assessment justifies its use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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