Product image of Lidocaïne Hcl B. Braun (Lidocaine Hydrochloride Monohydrate) supplied by GNH India

Lidocaïne Hcl B. Braun

Active Ingredient:
Lidocaine Hydrochloride Monohydrate
Origin:
EU

Lidocaïne Hcl B. Braun (Lidocaine Hydrochloride Monohydrate)

Lidocaine hydrochloride, the active ingredient in Lidocaïne Hcl B. Braun, is a local anesthetic (amide) presented as a sterile solution for intraosseous and intravenous use. It provides reversible nerve impulse blockade for minor surgical or diagnostic procedures and can be used intravenously to treat ventricular arrhythmias.

GNH India supplies Lidocaïne Hcl B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Lidocaine hydrochloride is a local anesthetic that acts on peripheral nerves and cardiac tissue to block abnormal electrical activity.

  • Minor surgical procedures: provides rapid, reversible local anesthesia for incision and excision.
  • Diagnostic procedures: offers analgesia for endoscopic or catheter‑based examinations.
  • Ventricular arrhythmias: stabilises cardiac rhythm when administered intravenously in emergency settings.

How It Works

  • Lidocaine hydrochloride reversibly binds to the intracellular portion of voltage‑gated sodium channels, stabilising the neuronal membrane and preventing the rapid influx of sodium ions required for depolarisation. This inhibition blocks the initiation and propagation of nerve impulses, producing local anaesthesia, and in cardiac tissue it suppresses abnormal automaticity and conduction, helping to control ventricular arrhythmias.

Side Effects

Adverse reactions may vary with the route of administration and patient factors.

Common Side Effects

  • Tingling or numbness at the injection site
  • Light‑headedness or dizziness
  • Nausea or vomiting
  • Metallic taste in the mouth
  • Local irritation or erythema
  • Transient visual disturbances

Serious or Rare Side Effects

  • Seizures, especially with high plasma concentrations
  • Cardiac conduction abnormalities such as bradycardia or heart block
  • Severe allergic reactions including anaphylaxis
  • Methemoglobinemia leading to cyanosis
  • Respiratory depression or apnea in overdose situations

Precautions & Warnings

Lidocaine should be used with careful clinical assessment and monitoring.

  • Cardiac history: evaluate for pre‑existing conduction disorders before intravenous use.
  • Hepatic function: adjust dosing in patients with severe liver impairment.
  • Hypersensitivity: avoid in individuals with known allergy to amide‑type local anesthetics.
  • Elderly patients: start with lower doses and monitor for toxicity.
  • Prolonged infusion: consider serum level monitoring to prevent accumulation.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Lidocaine may interact with other drugs that affect cardiac conduction or metabolism.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide) – additive cardiac toxicity.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin) – increase lidocaine plasma levels.
  • Amiodarone – potentiates lidocaine’s anti‑arrhythmic effect and risk of bradycardia.

Moderate Interactions (Monitor Closely)

  • Diuretics (e.g., furosemide) – may enhance lidocaine‑induced hypotension.
  • Anticonvulsants (e.g., phenytoin) – alter lidocaine metabolism.
  • Other local anesthetics – risk of cumulative systemic toxicity.

Frequently Asked Questions

Lidocaïne Hcl B. Braun contains lidocaine hydrochloride and is used to provide local anesthesia for minor surgical or diagnostic procedures, to give analgesia during invasive examinations, and, when given intravenously, to treat ventricular arrhythmias in emergency cardiac care.

Lidocaine blocks voltage‑gated sodium channels on nerve and cardiac cell membranes, preventing the rapid influx of sodium that initiates an action potential. This stops nerve impulse transmission for local anesthesia and reduces abnormal electrical activity in the heart, helping to control arrhythmias.

The appropriate dose is determined by the prescribing clinician based on the intended route (intraosseous or intravenous), the procedure, patient weight, age, and clinical condition. Dosing guidelines are provided in the product’s prescribing information and must be followed by a qualified health professional.

Safety data for lidocaine hydrochloride in pregnancy and lactation are limited, and the product’s pregnancy category is not established. Use only if the potential benefit justifies any potential risk to the fetus or infant, and consult a healthcare professional for individualized assessment.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and any required import documentation.

Lidocaine is an amide‑type local anesthetic with a rapid onset and moderate duration, making it suitable for short procedures and emergency cardiac use. Compared with ester‑type agents such as procaine, lidocaine has a lower risk of allergic reactions and a more predictable pharmacokinetic profile.

Lidocaïne Hcl B. Braun should be stored at room temperature, below 25 °C, in its original packaging. Protect the solution from moisture, direct sunlight and extreme temperatures. Do not freeze the product, and inspect the container for any signs of contamination before use.

The product is supplied as a sterile solution for intraosseous or intravenous injection. Administration is performed by a qualified healthcare professional using aseptic technique, with the dose and rate adjusted to the clinical indication and patient characteristics.

Serious risks include seizures, severe cardiac conduction disturbances (such as bradycardia or heart block), anaphylactic reactions, methemoglobinemia, and respiratory depression. Prompt recognition and supportive measures are essential if any of these events occur.

Patients with known hypersensitivity to lidocaine or other amide‑type local anesthetics, those with severe hepatic impairment, and individuals with certain pre‑existing cardiac conduction disorders should avoid this product unless a specialist determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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