Lidocaïne/Prilocaïne Bio Valys (Lidocaine, Prilocaine)

Both lidocaine and prilocaine block voltage‑gated sodium channels on peripheral nerves. By stabilising the channels in their inactivated state, they prevent sodium influx that is necessary for depolarisation, thereby halting the generation and propagation of nerve impulses. The result is a reversible loss of sensation in the area where the product is applied.

The appropriate amount and frequency of application are determined by the prescribing healthcare professional based on the specific procedure, treatment area and patient characteristics. No fixed dosing regimen can be provided here; clinicians should follow local guidelines and product labeling when prescribing.

Safety data for topical lidocaine/prilocaine use during pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made by the prescriber after evaluating the individual clinical situation.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Compared with single‑agent products such as benzocaine or tetracaine, the lidocaine‑prilocaine combination offers a broader spectrum of nerve block and a longer duration of action. It also tends to produce less mucosal irritation than benzocaine and provides more consistent anaesthesia than tetracaine for deeper dermal layers, making it a preferred choice for many minor surgical and dermatologic procedures.

Store the product at temperatures below 25 °C, in its original container, protected from moisture and direct light. Keep the packaging tightly closed when not in use and avoid exposing the cream or gel to excessive heat. Follow any additional handling instructions on the label to maintain product stability.

The preparation is applied topically to clean, intact skin. A thin layer is spread over the intended area, usually using a gloved fingertip or applicator, and left in place for the time recommended by the prescriber (often 5–30 minutes). The area should be covered with a non‑occlusive dressing only if directed, and the product should not be used on mucous membranes unless specifically indicated.

Serious adverse events, although rare, include systemic toxicity such as central nervous system symptoms (dizziness, seizures) and cardiovascular effects (arrhythmia, hypotension). Prilocaine can cause methemoglobinemia, a condition that reduces oxygen delivery in the blood. Severe allergic reactions, including contact dermatitis and anaphylaxis, also require immediate medical attention.

The product should be avoided in individuals with a known hypersensitivity to lidocaine, prilocaine or any amide‑type local anesthetic. It is also contraindicated on broken skin, extensive