Lidocaine With Adrenaline (Epinephrine) 1:200 000 Laboratoire Aguettant (Epinephrine, Lidocaine Hydrochloride)

Lidocaine blocks voltage‑gated sodium channels on nerve cells, stopping the transmission of pain signals. Epinephrine activates alpha‑adrenergic receptors causing vasoconstriction, which limits systemic absorption of lidocaine, extends its duration, and minimizes local bleeding.

The dose of lidocaine with epinephrine is determined by the prescribing clinician based on the specific procedure, patient weight, age, and clinical condition. Only a qualified health professional should set the appropriate dosage and administration schedule.

Safety data for lidocaine with epinephrine in pregnancy and lactation are limited. The medication should only be used if the potential benefit justifies any possible risk to the fetus or infant, and it must be prescribed by a qualified health professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any required import documentation.

Compared with plain lidocaine, the addition of epinephrine offers longer duration of anesthesia and reduced intra‑operative bleeding due to vasoconstriction. It may be preferred over other agents when prolonged effect and hemostasis are desired, though the choice depends on the clinical scenario and patient factors.

Store the sterile solution at room temperature, preferably below 25 °C. Keep the vial in its original packaging, protect it from direct light and moisture, and ensure the container is sealed when not in use to maintain sterility.

Lidocaine with epinephrine is administered by a qualified health professional via injection. Routes include epidural, infiltration, intravenous or perineural techniques, depending on the intended anesthetic effect and the specific procedure being performed.

Serious risks include severe allergic reactions (anaphylaxis), cardiac arrhythmias, seizures, and rare cases of methemoglobinemia. Immediate medical attention is required if any of these events occur during or after administration.

Patients with known hypersensitivity to lidocaine, epinephrine, or any component of the formulation should avoid this product. Caution is also advised for individuals with severe cardiac disease, uncontrolled hypertension, hyperthyroidism, or certain metabolic disorders, and the decision should be made by a healthcare professional.