Product image of Lidocaini Hydrochloridum Noridem (Lidocaine Hydrochloride Monohydrate) supplied by GNH India

Lidocaini Hydrochloridum Noridem

Active Ingredient:
Lidocaine Hydrochloride Monohydrate
Origin:
EU

Lidocaini Hydrochloridum Noridem (Lidocaine Hydrochloride Monohydrate)

Lidocaine Hydrochloride, the active ingredient in Lidocaini Hydrochloridum Noridem, is a local anesthetic presented as a sterile solution for epidural, intradermal and intramuscular use. It provides reversible nerve block for minor surgical, obstetric and diagnostic procedures in adult patients.
GNH India supplies Lidocaini Hydrochloridum Noridem as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Noridem Enterprises Ltd

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Indications & Clinical Uses

Lidocaine Hydrochloride is employed in the management of pain through local anesthetic action across several clinical settings.

  • Minor surgical procedures: produces rapid, reversible loss of sensation to facilitate incision and suturing.
  • Labor analgesia: enables epidural pain control during childbirth, improving maternal comfort.
  • Diagnostic procedures: provides infiltration anesthesia for biopsies, endoscopies and other minor interventions.

How It Works

  • Lidocaine Hydrochloride exerts its effect by reversibly binding to the intracellular portion of voltage‑gated sodium channels in neuronal membranes. This blockade prevents the influx of sodium ions during depolarization, thereby inhibiting the initiation and propagation of nerve impulses and producing a localized loss of sensation without affecting consciousness.

Side Effects

Adverse reactions may occur following administration of lidocaine hydrochloride.

Common Side Effects

  • Transient burning or stinging at the injection site.
  • Mild erythema or swelling around the administration area.
  • Dizziness or light‑headedness.

Serious or Rare Side Effects

  • Systemic toxicity manifesting as seizures or central nervous system depression.
  • Cardiac arrhythmias, including ventricular tachycardia.
  • Methemoglobinemia, a rare disorder affecting oxygen transport.

Precautions & Warnings

Prior to using lidocaine hydrochloride, clinicians should consider several safety measures.

  • Assess allergy: confirm no known hypersensitivity to amide‑type local anesthetics.
  • Monitor cardiovascular status: observe for signs of toxicity during high‑dose administration.
  • Use caution in patients with hepatic impairment: consider dose adjustment.
  • Avoid concurrent use with other sodium channel blockers: increased risk of cardiotoxicity.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Lidocaine hydrochloride can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine): may potentiate cardiotoxicity.
  • Beta‑blockers (e.g., propranolol): increase risk of severe hypotension.
  • General anesthetics (e.g., propofol): additive central nervous system depression.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs: may increase bleeding risk at injection site.
  • CYP3A4 inhibitors (e.g., erythromycin): may raise plasma lidocaine levels.

Frequently Asked Questions

Lidocaini Hydrochloridum Noridem contains lidocaine hydrochloride, a local anesthetic used to provide temporary loss of sensation for minor surgical procedures, epidural labor analgesia, and diagnostic interventions such as biopsies or endoscopies. It is administered by injection into the targeted tissue area.

Lidocaine hydrochloride blocks voltage‑gated sodium channels on neuronal membranes, preventing sodium influx during depolarization. This inhibition stops the generation and propagation of nerve impulses, resulting in a reversible, localized loss of pain sensation without affecting consciousness.

The specific dose of Lidocaini Hydrochloridum Noridem is determined by the prescribing clinician based on the procedure, patient weight, age, and clinical condition. Healthcare professionals calculate the appropriate amount to achieve effective anesthesia while minimizing toxicity.

Safety data for lidocaine hydrochloride in pregnancy and lactation are limited. It should only be used when clearly needed and after a risk‑benefit assessment by the prescriber. Breastfeeding mothers should consult their healthcare provider, as small amounts may be excreted in milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Lidocaine is an amide‑type local anesthetic with a rapid onset (1–3 minutes) and moderate duration (1–2 hours). Compared with agents such as bupivacaine, lidocaine has a shorter duration but a lower risk of cardiotoxicity, making it suitable for shorter procedures and epidural analgesia where quick recovery is desired.

Lidocaini Hydrochloridum Noridem should be stored at room temperature, below 25 °C, in its original sealed container. Protect the solution from direct sunlight, moisture and extreme temperatures to maintain sterility and potency.

The product is supplied as a sterile injectable solution and is administered by a qualified healthcare professional via epidural, intradermal or intramuscular injection, depending on the clinical indication. Proper aseptic technique and dosage calculation are essential for safe use.

Serious adverse events include systemic toxicity leading to seizures, cardiac arrhythmias, and, rarely, methemoglobinemia. These risks increase with high plasma concentrations, accidental intravascular injection, or when combined with other sodium channel blockers. Immediate medical attention is required if severe symptoms develop.

Patients with a known hypersensitivity to lidocaine, other amide‑type local anesthetics, or any component of the formulation should avoid this product. Caution is also advised for individuals with severe hepatic impairment, certain cardiac conduction disorders, or those receiving interacting medications listed under major interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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