Product image of Lidoject (Lidocaine Hydrochloride) supplied by GNH India

Lidoject

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidoject (Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Lidoject, is a local anesthetic presented as a sterile solution for intradermal use. It provides temporary loss of sensation to the skin and underlying tissues, facilitating minor surgical or diagnostic procedures in patients of all ages.

GNH India supplies Lidoject as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides regulatory documentation for importers. Its global logistics network ensures timely delivery across multiple continents.

Manufacturer / TM Owner

Hexal Ag

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Indications & Clinical Uses

  • Lidoject, a lidocaine‑based local anesthetic, is employed to achieve dermal anesthesia for a range of minor procedures.
  • Minor surgical procedures: provides rapid, reversible loss of sensation at the injection site, facilitating incision, excision or suturing of superficial tissues.
  • Diagnostic skin testing: numbs targeted skin areas to reduce discomfort during biopsies, lesion removal or intradermal testing.
  • Dental interventions: delivers localized anesthesia of oral mucosa for simple extractions, scaling or restorative work.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels in neuronal membranes, preventing the influx of sodium ions required for depolarisation. By stabilising the neuronal membrane, it inhibits initiation and propagation of nerve impulses, resulting in reversible loss of sensory perception in the administered area. The effect is concentration‑dependent and lasts until the drug is metabolised or diffused away.

Side Effects

Lidoject may be associated with a range of adverse reactions, varying from mild local irritation to rare systemic toxicity.

Common Side Effects

  • Pain or burning at the injection site
  • Redness or mild swelling
  • Transient tingling or numbness

Serious or Rare Side Effects

  • Cardiovascular toxicity (arrhythmia, bradycardia, cardiac arrest)
  • Central nervous system toxicity (seizures, loss of consciousness)
  • Severe allergic reactions (anaphylaxis, angio‑edema)

Precautions & Warnings

  • When using Lidoject, clinicians should observe several precautions to minimise risk and ensure safe administration.
  • Allergy assessment: verify no known hypersensitivity to amide‑type local anesthetics.
  • Cardiovascular status: avoid use in patients with severe heart block, conduction disorders, or uncontrolled arrhythmias.
  • Maximum dose: adhere to recommended total lidocaine dose limits for the patient’s weight and age.
  • Concurrent medications: exercise caution when other sodium‑channel blockers or class I antiarrhythmics are administered.
  • Pregnancy and lactation: consider use only when potential benefit justifies potential risk to the fetus or infant.
  • Store at ambient temperature: keep in original container, protect from light and moisture, and store below 25 °C.

Avoid Interactions

Lidoject can interact with other medicines, altering its safety profile or efficacy.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): increase risk of cardiotoxicity.
  • Other local anesthetics: additive systemic toxicity when combined.
  • Beta‑blockers: may potentiate cardiac depressant effects of lidocaine.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors (e.g., erythromycin, clarithromycin): may raise plasma lidocaine concentrations.
  • Diuretics (e.g., furosemide): can affect lidocaine clearance and plasma levels.
  • General anesthetics (e.g., propofol, volatile agents): require monitoring of hemodynamic status.

Frequently Asked Questions

Lidoject is a sterile lidocaine hydrochloride solution intended for intradermal injection to provide local anesthesia. It is commonly employed to numb the skin and superficial tissues during minor surgical interventions, diagnostic skin procedures, and simple dental treatments, allowing clinicians to perform these actions with reduced patient discomfort.

Lidocaine exerts its effect by blocking voltage‑gated sodium channels on neuronal membranes. This inhibition prevents sodium influx that is essential for the generation and propagation of action potentials, thereby halting nerve impulse transmission in the area where the drug is administered. The result is a reversible loss of sensation limited to the targeted tissue.

The appropriate dose of Lidoject is determined by the prescribing clinician based on the specific procedure, the size of the treatment area, and the patient’s age, weight, and overall health. Only a qualified healthcare professional should calculate and administer the amount, adhering to established maximum lidocaine dosage guidelines.

Safety data for lidocaine in pregnancy and lactation are limited, and the product is classified as category unknown. Consequently, Lidoject should only be used when the potential therapeutic benefit justifies any possible risk to the fetus or nursing infant, and the decision should be made by a qualified obstetric or pediatric specialist.

To place an order, visit the product page on gnhindia.com, submit an enquiry with the required quantity, and provide institutional or trade credentials. GNH India’s procurement team will verify the information, then respond with pricing, availability, shipping details—including any cold‑chain requirements—and the necessary import documentation.

Compared with other amide‑type local anesthetics such as bupivacaine, lidocaine offers a faster onset of action and a moderate duration of anesthesia, making it suitable for short‑duration procedures. Its safety profile is well‑established, though its duration is shorter than that of longer‑acting agents, which may be preferred for extended surgeries.

Lidoject should be stored at ambient temperature, preferably below 25 °C, in its original sealed container. Protect the product from direct sunlight, moisture, and extreme temperature fluctuations. Before use, inspect the solution for clarity and any particulate matter; discard if discoloration or contamination is observed.

Lidoject is administered by a trained healthcare professional via intradermal injection. The injection site is typically cleansed with an antiseptic, and a small gauge needle is used to deposit the solution into the superficial dermal layer. The volume injected depends on the size of the area to be anesthetized and the clinical protocol.

The most serious risks include systemic lidocaine toxicity, which can manifest as cardiovascular complications (arrhythmias, cardiac arrest) and central nervous system effects (seizures, loss of consciousness). Severe allergic reactions such as anaphylaxis and rare cases of methemoglobinemia also represent critical concerns that require immediate medical intervention.

Lidoject should be avoided in individuals with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, patients with severe cardiac conduction abnormalities, uncontrolled arrhythmias, or those receiving concurrent class I antiarrhythmic drugs. Caution is also advised for patients with significant hepatic impairment, as metabolism may be reduced.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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