Lidokain/Adrenalin Aguettant (Epinephrine, Lidocaine Hydrochloride)

Lidocaine blocks voltage‑gated sodium channels, halting nerve impulse transmission and producing numbness. Epinephrine stimulates alpha‑adrenergic receptors, causing vasoconstriction that reduces local blood flow, limits systemic absorption of lidocaine, and extends the anesthetic effect.

The specific dose is determined by the prescribing clinician based on the procedure, patient weight, and clinical setting. Healthcare professionals calculate the appropriate volume and concentration to achieve effective anesthesia while staying within safety limits.

Safety in pregnancy and lactation has not been definitively established. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with plain lidocaine solutions, the addition of epinephrine offers longer duration of action and reduced systemic absorption, which can lower toxicity risk. It is similar to other lidocaine‑epinephrine combinations but may differ in concentration, packaging, or regulatory status.

Store the product at temperatures below 25 °C, in its original container, protected from light and moisture. Avoid freezing and ensure the vial is kept upright to prevent leakage.

The solution is administered by a qualified healthcare professional via epidural, infiltration, or perineural injection techniques. Proper aseptic technique and dosage calculation are essential for safe and effective use.

Serious risks include severe allergic reactions (anaphylaxis), cardiac arrhythmias, hypertension or hypotension extremes, seizures, and rare cases of methemoglobinemia. Immediate medical attention is required if any of these events occur.

Patients with known hypersensitivity to lidocaine, epinephrine, or any component of the formulation should avoid this product. It is also contraindicated in individuals with certain cardiac conditions, uncontrolled hypertension, or those taking monoamine oxidase inhibitors without careful medical supervision.