Product image of Lidokain/Adrenalin Aguettant (Epinephrine, Lidocaine Hydrochloride) supplied by GNH India

Lidokain/Adrenalin Aguettant

Active Ingredient:
Epinephrine, Lidocaine Hydrochloride
Origin:
EU

Lidokain/Adrenalin Aguettant (Epinephrine, Lidocaine Hydrochloride)

Lidocaine hydrochloride, the active ingredient in Lidokain/Adrenalin Aguettant, is a local anesthetic presented as a sterile solution for epidural, infiltration, and perineural use. It provides temporary loss of sensation for minor surgical procedures and other indicated anesthetic applications.

GNH India supplies Lidokain/Adrenalin Aguettant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Aguettant

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Indications & Clinical Uses

Lidokain/Adrenalin is a local anesthetic combination used in procedures involving the peripheral and central nervous system pathways.

  • Minor surgical procedures: provides local anesthesia to facilitate the operation.
  • Infiltration anesthesia: numbs tissue for minor dermatologic or dental work.
  • Perineural (nerve block) anesthesia: blocks nerve transmission for targeted analgesia.
  • Epidural anesthesia: produces regional anesthesia for obstetric or surgical procedures.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing depolarization and impulse conduction. Epinephrine activates alpha‑adrenergic receptors causing vasoconstriction, which reduces systemic absorption of lidocaine, prolongs its anesthetic effect, and limits bleeding at the injection site.

Side Effects

Adverse reactions may occur following administration of Lidokain/Adrenalin.

Common Side Effects

  • Transient burning or stinging at the injection site
  • Mild dizziness or light‑headedness
  • Nausea or vomiting
  • Temporary tachycardia
  • Localized swelling or erythema
  • Headache

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Cardiac arrhythmia or myocardial ischemia
  • Seizures or central nervous system toxicity
  • Methemoglobinemia
  • Persistent hypotension
  • Respiratory depression

Precautions & Warnings

Before using Lidokain/Adrenalin, consider the following safety measures.

  • Allergy assessment: verify no known hypersensitivity to lidocaine or epinephrine.
  • Cardiovascular status: use cautiously in patients with heart disease or hypertension.
  • Pregnancy: avoid unless the potential benefit justifies the potential risk.
  • Drug interactions: review concomitant medications for possible additive effects.
  • Dosage limits: adhere to the prescriber's maximum recommended dose.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Lidokain/Adrenalin may interact with other medicines; monitor patients accordingly.

Major Interactions (Avoid)

  • Class I antiarrhythmic agents (e.g., quinidine): may increase lidocaine toxicity.
  • Beta‑blockers: can potentiate epinephrine‑induced hypertension.
  • Monoamine oxidase inhibitors: risk of hypertensive crisis.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs: may increase bleeding risk.
  • Diuretics: may alter plasma concentrations of lidocaine.
  • General anesthetics: may enhance central nervous system depression.

Frequently Asked Questions

Lidokain/Adrenalin is a prescription‑only local anesthetic combination containing lidocaine hydrochloride and epinephrine. It is used to provide regional or local anesthesia for minor surgical procedures, infiltration of tissues, perineural nerve blocks, and epidural anesthesia in various clinical settings.

Lidocaine hydrochloride blocks voltage‑gated sodium channels on nerve membranes, preventing the initiation and propagation of action potentials. This inhibition stops nerve impulse transmission, resulting in loss of sensation in the targeted area.

The specific dose of Lidokain/Adrenalin is determined by the prescribing clinician based on the procedure, patient characteristics, and route of administration. Only a qualified health professional should set the dosage and administration schedule.

Safety data for Lidokain/Adrenalin in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lidokain/Adrenalin combines lidocaine with epinephrine, which causes local vasoconstriction. This prolongs the anesthetic effect, reduces systemic absorption, and can decrease intra‑operative bleeding compared with lidocaine alone, making it useful for procedures where a longer duration of action is desired.

Store the product at room temperature, preferably below 25 °C, in its original packaging. Protect it from direct sunlight, moisture, and extreme temperatures. Do not freeze the solution, and keep it out of reach of children.

Lidokain/Adrenalin is administered by a qualified health professional via injection. It can be given epidurally, infiltratively, or perineurally, depending on the clinical indication and the targeted anatomical site.

Serious risks include severe allergic reactions (anaphylaxis), cardiac arrhythmias, seizures, and methemoglobinemia. Patients should be monitored for signs of toxicity, especially when high doses are used or when administered near highly vascular areas.

Individuals with a known hypersensitivity to lidocaine, epinephrine, or any component of the formulation should avoid this product. Caution is also advised for patients with severe cardiac disease, uncontrolled hypertension, or certain metabolic disorders, as determined by the prescribing clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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