Product image of Lidokain Aguettant (Lidocaine Hydrochloride) supplied by GNH India

Lidokain Aguettant

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidokain Aguettant (Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Lidokain Aguettant, is a local anesthetic presented as a sterile solution for infiltration, intradermal and intravenous use. It provides reversible nerve block for minor surgical and diagnostic procedures in patients requiring short‑term anesthesia.

GNH India supplies Lidokain Aguettant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Aguettant

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Indications & Clinical Uses

Lidocaine is a local anesthetic that temporarily blocks nerve conduction for minor procedures and regional techniques.

  • Local anesthesia for minor surgical or diagnostic procedures: provides temporary loss of sensation to facilitate the procedure.
  • Infiltration anesthesia: numbs a specific tissue area before incision or suturing.
  • Intravenous regional anesthesia (Bier block): creates a reversible nerve block in a limb for short surgeries.

How It Works

  • Lidocaine reversibly binds to voltage‑gated sodium channels on neuronal membranes, stabilizing the inactive state of the channel. This prevents the rapid influx of sodium ions required for depolarization, thereby inhibiting initiation and propagation of nerve impulses and producing a localized loss of sensation.

Side Effects

Lidocaine may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Tingling or numbness at the injection site.
  • Mild dizziness or light‑headedness.
  • Transient headache.
  • Nausea or mild gastrointestinal upset.
  • Localized swelling or erythema.

Serious or Rare Side Effects

  • Central nervous system toxicity (e.g., seizures, altered mental status).
  • Cardiovascular effects such as arrhythmias or hypotension.
  • Allergic reactions including rash, urticaria, or anaphylaxis.
  • Methemoglobinemia, especially with high doses.
  • Persistent numbness or motor weakness beyond the expected duration.

Precautions & Warnings

When using Lidokain Aguettant, consider the following safety measures.

  • Patient assessment: evaluate for known hypersensitivity to amide‑type local anesthetics.
  • Dose calculation: ensure total administered dose does not exceed recommended maximums for the patient’s weight and age.
  • Cardiac monitoring: observe patients with pre‑existing heart disease or those receiving large volumes.
  • Concurrent CNS depressants: use caution when combined with other agents that may lower seizure threshold.
  • Pregnancy and lactation: use only if the potential benefit justifies the potential risk, as safety data are limited.
  • Store at ambient temperature: keep below 25°C, in the original container, protected from moisture and direct sunlight.

Avoid Interactions

Lidocaine can interact with several medications, altering its safety profile.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may increase risk of cardiotoxicity.
  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): can raise plasma lidocaine levels.
  • Beta‑blockers: may potentiate cardiovascular depression.

Moderate Interactions (Monitor Closely)

  • Other local anesthetics: cumulative toxicity risk.
  • CNS depressants (e.g., benzodiazepines, opioids): may enhance sedation and seizure risk.
  • Diuretics: may affect plasma protein binding, altering free lidocaine concentration.

Frequently Asked Questions

Lidokain Aguettant contains lidocaine, a local anesthetic used to provide temporary loss of sensation for minor surgical or diagnostic procedures, infiltration anesthesia, and intravenous regional (Bier block) anesthesia. It is administered by infiltration, intradermal injection, or intravenous infusion under professional supervision.

Lidocaine blocks voltage‑gated sodium channels on nerve membranes, stabilizing them in an inactive state. This prevents the rapid influx of sodium ions needed for depolarization, thereby inhibiting the initiation and conduction of nerve impulses and producing a reversible, localized anesthetic effect.

The appropriate dose of Lidokain Aguettant is determined by the prescribing clinician based on the procedure, patient weight, age, and overall health. Healthcare professionals calculate the total allowable dose to stay within safety limits and adjust the volume administered accordingly.

Safety data for lidocaine in pregnancy and lactation are limited. The product should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and it should be prescribed by a qualified healthcare provider after careful assessment.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Lidocaine is an amide‑type local anesthetic with a rapid onset and moderate duration, making it suitable for many short procedures. Compared with ester‑type agents such as procaine, lidocaine has a lower incidence of allergic reactions and a more predictable pharmacokinetic profile, though alternatives like bupivacaine may offer longer lasting anesthesia.

Store Lidokain Aguettant at ambient temperature, preferably below 25 °C. Keep the vial in its original packaging, protect it from moisture, direct sunlight, and extreme temperatures. Do not freeze the solution, and ensure the container is sealed when not in use.

Lidokain Aguettant is supplied as a sterile solution for injection. It can be administered by infiltration into the target tissue, intradermally for superficial anesthesia, or intravenously for regional (Bier block) anesthesia. Administration is performed by qualified healthcare professionals following aseptic technique.

Serious risks include central nervous system toxicity (such as seizures), cardiovascular effects (including arrhythmias, hypotension, or cardiac arrest), severe allergic reactions (anaphylaxis), and methemoglobinemia. Prompt recognition and supportive management are essential if any of these events occur.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, those with severe cardiac conduction disorders, or individuals taking interacting medications that could raise lidocaine levels (e.g., class I antiarrhythmics) should avoid its use unless a specialist determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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