Product image of Lidokain-Fluorescein Bausch & Lomb (Fluorescein Sodium, Lidocaine Hydrochloride) supplied by GNH India

Lidokain-Fluorescein Bausch & Lomb

Active Ingredient:
Fluorescein Sodium, Lidocaine Hydrochloride
Origin:
EU

Lidokain-Fluorescein Bausch & Lomb (Fluorescein Sodium, Lidocaine Hydrochloride)

Fluorescein Sodium and Lidocaine Hydrochloride, the active ingredients in Lidokain-Fluorescein, are local anesthetic and ophthalmic diagnostic agents presented as an ophthalmic solution for ocular use. They provide topical anesthesia and allow visualization of corneal defects in patients undergoing minor eye examinations or procedures.

GNH India supplies Lidokain-Fluorescein as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

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Indications & Clinical Uses

Lidokain-Fluorescein is used in ophthalmology for diagnostic staining and temporary anesthesia of the ocular surface.

  • Diagnostic staining of cornea and conjunctiva: enables visualization of epithelial defects, foreign bodies and tear‑film abnormalities.
  • Topical ocular anesthesia for minor procedures: provides temporary numbness for slit‑lamp examinations, foreign‑body removal, or laser treatments.
  • Assessment of tear‑film integrity: fluorescein staining helps evaluate dry‑eye severity and corneal health.

How It Works

  • Lidocaine hydrochloride blocks voltage‑gated sodium channels on peripheral nerve endings, producing reversible loss of sensation on the ocular surface. Fluorescein sodium binds to extracellular proteins and stains damaged epithelial cells, creating a fluorescent contrast that is visible under cobalt‑blue illumination, facilitating detection of corneal and conjunctival lesions.

Side Effects

Adverse reactions may occur following ocular application of Lidokain-Fluorescein.

Common Side Effects

  • Stinging or burning sensation at the application site.
  • Transient blurred vision.
  • Mild conjunctival hyperemia.
  • Temporary eyelid edema.
  • Mild ocular discomfort.

Serious or Rare Side Effects

  • Allergic reactions including anaphylaxis.
  • Severe corneal toxicity or persistent epithelial defect.
  • Significant rise in intra‑ocular pressure.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Vision loss if severe toxicity occurs.

Precautions & Warnings

Before using Lidokain-Fluorescein, consider the following safety measures.

  • Allergy assessment: avoid in patients with known hypersensitivity to lidocaine or fluorescein.
  • Contact lens wear: remove lenses before application to prevent staining and irritation.
  • Pregnancy and lactation: use only if the potential benefit justifies the potential risk; data are limited.
  • Concurrent ocular medications: avoid mixing with other ophthalmic solutions unless directed by a clinician.
  • Storage: Store at room temperature below 25°C: keep in the original container, protect from light and moisture.

Avoid Interactions

Lidokain-Fluorescein may interact with other ophthalmic agents.

Major Interactions (Avoid)

  • Topical anesthetic eye drops containing preservatives: increased risk of corneal toxicity.
  • Systemic lidocaine‑containing products: may potentiate systemic lidocaine effects if large ocular surface area is treated.

Moderate Interactions (Monitor Closely)

  • Anticholinergic eye drops: may reduce fluorescein staining quality.
  • Beta‑blocker eye drops: monitor intra‑ocular pressure changes.
  • Proton pump inhibitors: no direct interaction but monitor for systemic absorption in extensive use.

Frequently Asked Questions

Lidokain-Fluorescein is an ophthalmic solution that combines a local anesthetic with a diagnostic dye. It is used to numb the ocular surface for minor procedures and to stain the cornea and conjunctiva, allowing clinicians to detect epithelial defects, foreign bodies, and tear‑film abnormalities during eye examinations.

Lidocaine hydrochloride blocks voltage‑gated sodium channels on sensory nerves, producing temporary loss of sensation on the eye surface. Fluorescein sodium adheres to damaged epithelial cells and fluoresces under cobalt‑blue light, creating a visible contrast that highlights corneal and conjunctival lesions for diagnostic evaluation.

The prescribed dose of Lidokain-Fluorescein is determined by the treating eye‑care professional based on the specific procedure or diagnostic need. The clinician will decide the volume and frequency of application appropriate for each patient.

Safety data for Lidokain-Fluorescein in pregnancy and lactation are limited. It should be used only if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by a qualified health‑care provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Lidokain-Fluorescein combines both anesthetic and staining functions in a single formulation, reducing the need for separate drops. Compared with using lidocaine alone, it offers diagnostic visualization, and compared with fluorescein alone, it provides temporary anesthesia, making it convenient for procedures that require both effects.

The product should be stored at room temperature below 25 °C, in its original container, protected from light and moisture. Avoid freezing or exposing the solution to extreme temperatures, and keep the vial tightly sealed when not in use.

Lidokain-Fluorescein is applied topically to the ocular surface as a drop or small volume of solution. The eye should be examined after a brief waiting period to allow anesthesia to take effect and the dye to stain the cornea, after which the clinician proceeds with the intended diagnostic or therapeutic procedure.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, significant corneal toxicity leading to persistent epithelial defects, and a marked increase in intra‑ocular pressure. Any signs of severe eye pain, vision loss, or systemic allergic symptoms require immediate medical attention.

Patients with a known hypersensitivity to lidocaine, fluorescein, or any component of the formulation should avoid using this product. It is also contraindicated in individuals with active severe ocular infections or inflammation where staining could mask disease progression.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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