Product image of Lidokainklorid B. Braun (Lidocaine Hydrochloride) supplied by GNH India

Lidokainklorid B. Braun

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidokainklorid B. Braun (Lidocaine Hydrochloride)

Lidocaine Hydrochloride, the active ingredient in Lidokainklorid B. Braun, is a local anesthetic presented as a sterile solution for epidural use. It provides reversible nerve block for surgical, obstetric and other procedural pain management in adult patients.
GNH India supplies Lidokainklorid B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

B.Braun Adria D.O.O.

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Indications & Clinical Uses

Lidokainklorid B. Braun is a local anesthetic used in the epidural pathway to achieve regional analgesia.

  • Epidural anesthesia: Produces loss of sensation in the lower body for surgical or obstetric procedures.
  • Intra‑operative pain control: Provides analgesia during major abdominal or orthopedic surgery.
  • Obstetric analgesia: Relieves labor pain while preserving maternal consciousness and motor function.

How It Works

  • Lidocaine Hydrochloride acts by reversibly binding to voltage‑gated sodium channels on neuronal membranes, stabilising the inactive state of the channel. This blocks the rapid influx of sodium ions required for depolarisation, thereby preventing the initiation and propagation of nerve impulses and producing a localized loss of sensation.

Side Effects

Lidokainklorid B. Braun may cause a range of adverse reactions.

Common Side Effects

  • Tingling or numbness at the injection site
  • Light‑headedness or dizziness
  • Nausea or vomiting
  • Transient hypotension
  • Metallic taste in the mouth
  • Headache

Serious or Rare Side Effects

  • Seizures or convulsions
  • Cardiac arrhythmias, including ventricular tachycardia
  • Respiratory depression or arrest
  • Methemoglobinemia
  • Severe allergic reaction (anaphylaxis)
  • Cardiovascular collapse

Precautions & Warnings

When using Lidokainklorid B. Braun, clinicians should observe several safety measures.

  • Assess patient allergy: Verify no known hypersensitivity to amide‑type local anesthetics.
  • Evaluate cardiac history: Use caution in patients with conduction disorders or heart disease.
  • Monitor dosage: Avoid exceeding recommended maximum cumulative dose to reduce toxicity risk.
  • Observe neurologic status: Watch for signs of central nervous system toxicity such as tinnitus or confusion.
  • Store below 25°C: Keep in the original container, protect from light and moisture.

Avoid Interactions

Lidokainklorid B. Braun can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): Increased risk of cardiotoxicity and arrhythmias.
  • Beta‑blockers combined with high‑dose lidocaine: May potentiate bradycardia and hypotension.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors (e.g., erythromycin, ketoconazole): May raise plasma lidocaine levels.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): Potential additive effect on bleeding risk.
  • General anesthetics (e.g., propofol, volatile agents): May enhance central nervous system depression.

Frequently Asked Questions

Lidokainklorid B. Braun is a lidocaine hydrochloride solution intended for epidural administration. It is used to provide regional anesthesia during surgical procedures, to control pain during obstetric labor, and to offer intra‑operative analgesia for various operations requiring a reversible loss of sensation in the lower body.

Lidocaine hydrochloride blocks voltage‑gated sodium channels on nerve membranes, stabilising them in an inactive state. This prevents the rapid influx of sodium ions needed for depolarisation, thereby inhibiting the generation and propagation of nerve impulses and producing a localized anesthetic effect.

The appropriate dose of Lidokainklorid B. Braun is determined by the prescribing clinician based on the specific procedure, patient characteristics, and desired level of anesthesia. Healthcare professionals calculate the volume and concentration required to achieve safe and effective epidural analgesia.

Safety data for lidocaine hydrochloride in pregnancy and lactation are limited. It may be used when the potential benefit justifies the potential risk to the fetus or infant, but clinicians should evaluate each case individually and follow local regulatory guidance.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Lidokainklorid B. Braun contains lidocaine, an amide‑type local anesthetic with a rapid onset and intermediate duration of action. Compared with bupivacaine, lidocaine has a shorter duration but a lower risk of cardiotoxicity at equivalent doses, making it suitable for procedures requiring quicker recovery of sensation.

The product should be stored below 25 °C in its original packaging, protected from light and moisture. Do not freeze the solution. Before use, inspect the vial for particulate matter or discoloration and ensure aseptic technique during epidural administration.

Lidokainklorid B. Braun is administered by a qualified healthcare professional via epidural injection. The sterile solution is injected into the epidural space using a catheter or needle under aseptic conditions, with the dose adjusted to achieve the desired level of sensory block while monitoring the patient closely.

Serious risks include central nervous system toxicity such as seizures, cardiovascular complications like arrhythmias or cardiac arrest, severe allergic reactions (anaphylaxis), and rare cases of methemoglobinemia. Prompt recognition and management of these events are essential during and after administration.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, those with severe heart block, uncontrolled epilepsy, or significant hepatic impairment should avoid this product. Clinicians must also exercise caution in patients with low plasma protein levels or concurrent use of drugs that affect lidocaine metabolism.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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