Product image of Lidonostrum (Lidocaine Hydrochloride) supplied by GNH India

Lidonostrum

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lidonostrum (Lidocaine Hydrochloride)

Lidocaine Hydrochloride, the active ingredient in Lidonostrum, is a local anesthetic presented as a formulation for buccal and gingival use. It provides local anesthesia of the oral mucosa and pain relief during dental procedures.

GNH India supplies Lidonostrum as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sidefarma - Sociedade Industrial De Expansão Farmacêutica, S.A.

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Indications & Clinical Uses

Lidonostrum is a local anesthetic that acts on the oral mucosal nerves to provide temporary loss of sensation.

  • Oral mucosal anesthesia: numbs the oral mucosa for minor surgical or diagnostic procedures.
  • Dental extraction pain relief: reduces pain during tooth removal.
  • Periodontal therapy: facilitates comfort during gingival manipulation and scaling.

How It Works

  • Lidocaine hydrochloride blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of action potentials. By inhibiting nerve impulse conduction in the targeted area, it produces reversible loss of sensation and analgesia localized to the site of application.

Side Effects

Adverse reactions may occur following buccal or gingival application of lidocaine.

Common Side Effects

  • Mild burning or stinging sensation at the application site.
  • Transient numbness lasting longer than the intended procedure.
  • Altered taste perception.
  • Localized swelling or mild irritation.
  • Redness of the mucosa.

Serious or Rare Side Effects

  • Allergic reaction such as rash, urticaria, or angioedema.
  • Cardiac arrhythmias including ventricular tachycardia.
  • Central nervous system toxicity manifesting as seizures.
  • Severe hypotension.
  • Methemoglobinemia (very rare).

Precautions & Warnings

Before using Lidonostrum, consider the following safety measures.

  • Allergy assessment: verify no known hypersensitivity to amide‑type local anesthetics.
  • Cardiac history: use with caution in patients with conduction disorders or arrhythmias.
  • Concomitant drugs: review medications that may lower seizure threshold.
  • Pregnancy and lactation: prescribe only if the anticipated benefit justifies potential risk.
  • Store below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Lidonostrum may interact with other medicines; monitor patients accordingly.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine): increased risk of systemic toxicity.
  • Beta‑blockers (e.g., propranolol): may potentiate cardiotoxic effects.

Moderate Interactions (Monitor Closely)

  • Monoamine oxidase inhibitors: possible enhancement of central nervous system effects.
  • Tricyclic antidepressants: may raise seizure risk.
  • Alcohol: can augment local anesthetic toxicity.

Frequently Asked Questions

Lidonostrum is a lidocaine hydrochloride product intended for local anesthesia of the oral mucosa and for pain relief during dental procedures such as extractions, scaling, and minor surgical interventions.

Lidocaine hydrochloride blocks voltage‑gated sodium channels on peripheral nerves, preventing the generation and propagation of action potentials. This interruption of nerve signaling results in a reversible loss of sensation in the area where it is applied.

The dose of Lidonostrum is determined by the prescribing clinician based on the procedure, the size of the treatment area, and the patient’s overall health. No fixed regimen is provided; the prescriber sets the appropriate amount.

Safety data for lidocaine hydrochloride in pregnancy and lactation are limited. It should be used only when the expected benefit outweighs any potential risk to the fetus or infant, and the decision should be made by a qualified health professional.

To order Lidonostrum, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lidonostrum (lidocaine) is an amide‑type local anesthetic offering rapid onset and moderate duration of action. Compared with ester‑type agents such as benzocaine, lidocaine generally provides deeper anesthesia, lower allergenic potential, and a well‑characterised safety profile.

Store Lidonostrum below 25 °C in its original packaging, protecting it from moisture and direct light. Avoid exposing the product to extreme temperatures or humidity, and keep it out of reach of children.

Lidonostrum is applied directly to the buccal or gingival mucosa using a suitable applicator. The clinician spreads a thin layer over the target area, allowing the drug to penetrate the tissue and produce localized numbness.

Serious risks include allergic reactions (e.g., rash, angioedema), systemic toxicity leading to cardiac arrhythmias, central nervous system effects such as seizures, and, in rare cases, methemoglobinemia. Immediate medical attention is required if any of these occur.

Lidonostrum should be avoided in individuals with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, patients with severe cardiac conduction disorders, and those with a history of seizures unless the benefit clearly outweighs the risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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