Product image of Lidoposterin Kade (Lidocaine) supplied by GNH India

Lidoposterin Kade

Active Ingredient:
Lidocaine
Origin:
EU

Lidoposterin Kade (Lidocaine)

Lidocaine, the active ingredient in Lidoposterin Kade, is a local anesthetic presented as a rectal preparation for local anesthesia use. It provides reversible nerve block to reduce pain sensation during minor rectal procedures and diagnostic examinations or therapeutic interventions in clinical settings while facilitating procedural efficiency and improving patient comfort.

GNH India supplies Lidoposterin Kade as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, clinics, and pharmacies worldwide, ensuring consistent quality, regulatory compliance, and reliable logistics for global healthcare providers.

Manufacturer / TM Owner

Dr. Kade Pharmazeutische Fabrik Gmbh

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Indications & Clinical Uses

Lidoposterin Kade, a local anesthetic, is employed to achieve temporary loss of sensation in the rectal mucosa for various procedures.

  • Hemorrhoidectomy: provides localized anesthesia to reduce procedural pain.
  • Anal fissure treatment: numbs the affected area to facilitate conservative management.
  • Endoscopic rectal examination: ensures patient comfort during diagnostic scopes.
  • Minor rectal surgeries: offers rapid onset analgesia for short‑duration interventions.
  • Proctologic biopsies: enables painless tissue sampling.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of action potentials. By stabilizing the neuronal membrane, it inhibits nerve impulse transmission, resulting in reversible loss of sensation in the targeted area without affecting surrounding tissues.

Side Effects

Lidoposterin Kade may cause a range of adverse reactions following rectal administration.

Common Side Effects

  • Burning or stinging at the application site
  • Local itching or erythema
  • Mild dizziness or light‑headedness
  • Nausea or mild gastrointestinal discomfort
  • Transient headache
  • Temporary numbness extending beyond the intended area

Serious or Rare Side Effects

  • Seizures or convulsions
  • Cardiac arrhythmias, including ventricular tachycardia
  • Respiratory depression or apnea
  • Methemoglobinemia
  • Severe allergic reactions such as anaphylaxis
  • Persistent numbness or paresthesia lasting beyond the expected duration

Precautions & Warnings

Prior to using Lidoposterin Kade, consider the following safety measures.

  • Allergy assessment: verify no known hypersensitivity to lidocaine or amide‑type anesthetics.
  • Cardiac history: caution in patients with conduction disorders or recent myocardial infarction.
  • Liver function: adjust use in severe hepatic impairment due to altered metabolism.
  • Dosage limits: adhere strictly to prescribed amount to avoid systemic toxicity.
  • Concomitant CNS depressants: monitor for additive central nervous system effects.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Lidoposterin Kade can interact with other medications, influencing its safety profile.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may markedly increase plasma lidocaine levels.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): can reduce lidocaine metabolism.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may enhance lidocaine's cardiac depressant effects.
  • Other local anesthetics: concurrent use can raise risk of systemic toxicity.
  • Diuretics (e.g., furosemide): may lower serum potassium, predisposing to arrhythmias.
  • Anticonvulsants: monitor for additive CNS effects.

Frequently Asked Questions

Lidoposterin Kade is a lidocaine‑based product designed for rectal administration to provide local anesthesia during minor rectal procedures, diagnostic endoscopies, hemorrhoidectomy, and other proctologic interventions where temporary pain relief is required.

Lidocaine blocks voltage‑gated sodium channels on nerve fibers, preventing the initiation and spread of action potentials. This results in a reversible loss of sensation in the treated area, allowing procedures to be performed with minimal discomfort.

The appropriate dose of Lidoposterin Kade is determined by the prescribing clinician based on the specific procedure, patient characteristics, and clinical guidelines. Healthcare professionals should follow the recommended dosing instructions on the product label.

Safety data for rectal lidocaine in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lidoposterin Kade contains lidocaine, an amide‑type anesthetic known for rapid onset and moderate duration. Compared with ester‑type agents such as procaine, lidocaine generally offers a faster onset, longer analgesic window, and a lower incidence of allergic reactions.

Store Lidoposterin Kade at room temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture and direct sunlight, and ensure the packaging remains sealed until use.

The product is applied rectally, typically as a gel, ointment, or suppository, depending on the specific formulation. Administration is performed by a qualified healthcare professional who applies the appropriate amount to the target area before the procedure.

Serious adverse events, although rare, include seizures, severe cardiac arrhythmias, respiratory depression, methemoglobinemia, and anaphylactic reactions. Immediate medical attention is required if any of these symptoms occur.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, those with severe hepatic impairment, or individuals with certain cardiac conduction disorders should avoid using Lidoposterin Kade unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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