Product image of Lidoproct (Lidocaine) supplied by GNH India

Lidoproct

Active Ingredient:
Lidocaine
Origin:
EU

Lidoproct (Lidocaine)

Lidocaine, the active ingredient in Lidoproct, is a local anesthetic presented as a rectal formulation for topical analgesia. It provides temporary numbing of the anorectal region and is used to alleviate pain associated with haemorrhoids, anal fissures and other proctologic procedures.

GNH India supplies Lidoproct as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for export to EU and other markets. Customers benefit from reliable logistics and on‑time delivery across multiple continents.

Manufacturer / TM Owner

Galenpharma Gmbh

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Indications & Clinical Uses

Lidoproct (lidocaine) is applied rectally to provide local anesthesia for anorectal conditions.

  • Haemorrhoidal disease: reduces pain and discomfort during flare‑ups.
  • Anal fissure: provides temporary numbness to facilitate bowel movements and healing.
  • Post‑operative anorectal surgery: alleviates procedural pain and spasm.
  • Proctalgia fugax: diminishes episodic rectal pain attacks.

How It Works

  • Lidocaine reversibly blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of nerve impulses. By stabilising the neuronal membrane, it interrupts the transmission of pain signals from the anorectal mucosa, resulting in localized loss of sensation without affecting systemic nerve function when used at recommended doses.

Side Effects

Lidoproct may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Burning or stinging at the application site.
  • Local irritation or redness.
  • Transient numbness extending beyond the intended area.
  • Mild dizziness or headache.

Serious or Rare Side Effects

  • Allergic reactions such as rash, swelling, or anaphylaxis.
  • Seizures or convulsions due to systemic toxicity.
  • Cardiac arrhythmias, including bradycardia or ventricular disturbances.

Precautions & Warnings

Before using Lidoproct, consider the following safety measures.

  • Allergy assessment: confirm no known hypersensitivity to lidocaine or amide‑type anesthetics.
  • Dosage limitation: use only the amount prescribed to avoid systemic toxicity.
  • Concurrent anesthetics: avoid using other topical or injectable local anesthetics simultaneously.
  • Medical conditions: exercise caution in patients with hepatic impairment or cardiac conduction disorders.
  • Pregnancy and lactation: discuss potential risks with a healthcare professional before use.
  • Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Lidoproct can interact with other medications; awareness of potential interactions helps prevent adverse effects.

Major Interactions (Avoid)

  • Other local anesthetics (e.g., bupivacaine, benzocaine): risk of cumulative systemic toxicity.
  • Class I antiarrhythmic agents (e.g., quinidine, procainamide): may enhance cardiac conduction disturbances.
  • Strong CYP1A2 or CYP3A4 inhibitors (e.g., cimetidine, erythromycin): increase lidocaine plasma levels.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers (e.g., propranolol): may potentiate bradycardia.
  • Central nervous system depressants (e.g., benzodiazepines, alcohol): can augment sedation and dizziness.
  • Diuretics (e.g., furosemide): may lower plasma protein binding, modestly raising free lidocaine concentration.

Frequently Asked Questions

Lidoproct is a rectally administered formulation of lidocaine that provides local anesthesia for anorectal discomfort. It is commonly employed to relieve pain associated with haemorrhoids, anal fissures, post‑operative pain after anorectal surgery, and episodic rectal cramps such as proctalgia fugax.

Lidocaine blocks voltage‑gated sodium channels on nerve membranes, preventing the rapid influx of sodium ions that initiates an action potential. By stabilising the neuronal membrane, it stops the transmission of pain signals from the treated area, producing a temporary loss of sensation without affecting consciousness.

The appropriate dose of Lidoproct is determined by the prescribing clinician based on the patient’s condition, age, and overall health. Healthcare professionals select the quantity and frequency that best balances analgesic benefit with safety, and patients should follow the exact instructions provided on the prescription label.

Safety data for rectal lidocaine during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lidoproct, as the prescriber may decide to avoid or adjust therapy.

To request Lidoproct, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs), and the necessary import documentation.

Lidoproct contains lidocaine, an amide‑type local anesthetic, which typically offers a faster onset and longer duration of numbness than ester‑type agents such as benzocaine. Compared with systemic analgesics, lidocaine provides targeted pain relief with minimal systemic exposure, reducing the risk of gastrointestinal side effects common to oral NSAIDs.

Lidoproct should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to extreme heat or humidity, which could compromise its stability and efficacy.

Lidoproct is inserted rectally, typically using a gloved finger or an applicator as directed by the prescriber. The patient should lie on their side with knees drawn toward the chest, gently push the suppository into the rectum, and remain in that position for a few minutes to ensure proper placement and absorption.

The most serious risks associated with Lidoproct include systemic toxicity leading to seizures or cardiac arrhythmias, and severe allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience symptoms like uncontrolled shaking, faintness, irregular heartbeat, difficulty breathing, or widespread rash after use.

Lidoproct should be avoided by individuals with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, patients with severe cardiac conduction disorders, and those with significant hepatic impairment that could impair drug metabolism. Consultation with a healthcare professional is essential before use in these populations.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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