Product image of Lifog (Latanoprost) supplied by GNH India

Lifog

Active Ingredient:
Latanoprost
Origin:
EU

Lifog (Latanoprost)

Latanoprost, the active ingredient in Lifog, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It lowers intra‑ocular pressure and is indicated for the treatment of open‑angle glaucoma and ocular hypertension in adult patients. The medication works by enhancing fluid outflow from the eye, helping to preserve visual function.

GNH India supplies Lifog as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. Our distribution network ensures consistent quality and regulatory compliance across EU and global markets.

Manufacturer / TM Owner

Alfa Intes Industria Terapeutica Splendore Via Fratelli

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Indications & Clinical Uses

Latanoprost is a prostaglandin analog used to manage ocular pressure in glaucoma and related conditions.

  • Open-angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent development of glaucoma.
  • Pseudoexfoliative glaucoma: improves fluid outflow to control intra‑ocular pressure.

How It Works

  • Latanoprost acts as an agonist at the prostaglandin F (FP) receptors in the ciliary muscle. Activation of FP receptors remodels the extracellular matrix, increasing uveoscleral outflow of aqueous humor. The enhanced outflow reduces intra‑ocular pressure, thereby helping to protect the optic nerve from glaucomatous damage. This mechanism is independent of beta‑adrenergic pathways and provides a sustained pressure‑lowering effect with once‑daily dosing.

Side Effects

Latanoprost may cause ocular and systemic adverse reactions; the frequency varies among patients.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Increased eyelash growth: longer, thicker lashes.
  • Iris pigmentation: gradual darkening of eye color.

Serious or Rare Side Effects

  • Severe ocular inflammation: uveitis or iritis requiring treatment.
  • Paradoxical intra‑ocular pressure increase: unexpected rise in pressure.
  • Macular edema: fluid accumulation affecting central vision.

Precautions & Warnings

When prescribing Latanoprost, clinicians should consider several precautionary measures to ensure patient safety.

  • Pregnancy: safety not established; avoid unless benefit outweighs risk.
  • Breastfeeding: unknown excretion; consider potential risk to infant.
  • Ocular surgery: postpone elective procedures for at least four weeks after discontinuation.
  • Intra‑ocular pressure monitoring: assess response regularly after initiation.
  • Active ocular infection: do not use until infection resolved.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Latanoprost can interact with other ophthalmic or systemic agents; awareness of these interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Concomitant use with other intra‑ocular pressure‑lowering agents may cause excessive hypotension.
  • Combination with non‑steroidal anti‑inflammatory eye drops can increase ocular irritation.
  • Simultaneous systemic carbonic anhydrase inhibitors may lead to overly low eye pressure.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: monitor for additive pressure reduction.
  • Alpha‑agonist eye drops: observe for combined hypotensive effect.

Frequently Asked Questions

Lifog contains latanoprost, a prostaglandin analog indicated for lowering intra‑ocular pressure in adults with open‑angle glaucoma and ocular hypertension. By reducing pressure, it helps to slow disease progression and protect the optic nerve from damage.

Latanoprost binds to prostaglandin F (FP) receptors in the eye, triggering remodeling of the extracellular matrix in the ciliary body. This increases uveoscleral outflow of aqueous humor, which lowers intra‑ocular pressure and reduces the risk of glaucomatous optic‑nerve injury.

The prescribed dose of Lifog is determined by the treating ophthalmologist. In clinical practice the medication is typically instilled as one drop in the affected eye(s) once daily in the evening, but the exact regimen should follow the prescriber’s instructions.

Safety data for latanoprost in pregnancy and lactation are limited. It is generally advised to avoid use during pregnancy unless the potential benefit justifies the risk, and to consider possible exposure to a nursing infant before prescribing to breastfeeding mothers.

To order Lifog, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lifog (latanoprost) belongs to the prostaglandin analog class, which typically offers once‑daily dosing and a strong pressure‑lowering effect. Compared with beta‑blocker drops such as timolol, latanoprost often provides greater IOP reduction and a different side‑effect profile, including cosmetic changes like iris darkening.

Lifog should be stored at room temperature, below 25 °C, in its original container. Protect the bottle from light and moisture, and keep the cap tightly closed when not in use to maintain sterility and potency.

Lifog is applied as an ophthalmic solution. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place one drop into the conjunctival sac of the prescribed eye(s). Close the eye gently for a few seconds and avoid blinking excessively.

Serious adverse events, although rare, include severe ocular inflammation such as uveitis or iritis, paradoxical increase in intra‑ocular pressure, and macular edema that can affect central vision. Prompt medical evaluation is required if any of these symptoms arise.

Lifog is contraindicated in patients with known hypersensitivity to latanoprost or any component of the formulation. It should also be avoided in individuals with active ocular infections, recent ocular surgery (unless cleared by a physician), and in pregnant or nursing women unless the benefit outweighs potential risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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