Product image of Lignocainum Jelfa (Lidocaine Hydrochloride) supplied by GNH India

Lignocainum Jelfa

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lignocainum Jelfa (Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Lignocainum Jelfa, is a local anesthetic presented as a sterile solution for urethral use. It provides reversible nerve impulse blockade to achieve temporary loss of sensation during urethral procedures in adult patients, and is intended for single‑use application by qualified healthcare professionals.

GNH India supplies Lignocainum Jelfa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Bausch Health Ireland Limited

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Indications & Clinical Uses

  • Lignocainum Jelfa, a lidocaine‑based local anesthetic, is used to provide anesthesia for procedures involving the urethral mucosa.
  • Urethral instrumentation: provides topical anesthesia to reduce discomfort during catheterization, cystoscopy, or urethral dilation.
  • Urethral surgery: facilitates pain‑free operative field during transurethral resection or other surgical interventions.
  • Urethral diagnostic procedures: enables patient tolerance during endoscopic evaluation of the urinary tract.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the rapid influx of sodium ions required for depolarization. This reversible inhibition stops the propagation of nerve impulses, resulting in loss of sensation in the area where the drug is applied, without affecting surrounding tissues.

Side Effects

Common Side Effects

  • Burning or stinging sensation at the application site.
  • Mild local irritation or erythema.
  • Transient numbness lasting beyond the procedure.
  • Dizziness or light‑headedness.
  • Taste disturbance if the solution contacts oral mucosa.
  • Mild hypotension in sensitive individuals.

Serious or Rare Side Effects

  • Central nervous system toxicity (e.g., tinnitus, seizures, loss of consciousness).
  • Cardiac arrhythmias or conduction disturbances.
  • Severe allergic reaction (anaphylaxis, angioedema).
  • Methemoglobinemia leading to cyanosis.
  • Persistent numbness beyond expected duration.
  • Respiratory depression in cases of systemic absorption.

Precautions & Warnings

Before use, consider the following precautions:

  • Allergy assessment: verify no known hypersensitivity to amide‑type local anesthetics.
  • Dosage calculation: ensure administered volume does not exceed recommended maximum for urethral use.
  • Patient monitoring: observe for signs of systemic toxicity such as tinnitus, circumoral numbness, or seizures.
  • Concurrent medications: avoid simultaneous use with other sodium channel blockers.
  • Pregnancy and lactation: use only if the benefit outweighs the potential risk, as safety data are limited.
  • Store at ambient temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Lignocainum Jelfa may interact with other medicines. Review the following interactions:

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may increase lidocaine plasma levels and risk of toxicity.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): can raise lidocaine concentrations.
  • Beta‑blockers (e.g., propranolol) when combined with high doses may potentiate central nervous system effects.

Moderate Interactions (Monitor Closely)

  • CYP1A2 inducers (e.g., carbamazepine): may reduce lidocaine efficacy.
  • Concurrent use of other local anesthetics: additive toxicity risk.
  • Loop diuretics (e.g., furosemide): may increase plasma lidocaine levels.

Frequently Asked Questions

Lignocainum Jelfa is a lidocaine‑based sterile solution used to provide local anesthesia during urethral procedures such as catheterization, cystoscopy, dilation, and transurethral surgeries. It temporarily blocks sensation in the urethral mucosa, helping to reduce patient discomfort and facilitate safe medical interventions.

Lidocaine works by reversibly blocking voltage‑gated sodium channels on nerve cells. This inhibition prevents the rapid influx of sodium ions needed for depolarization, thereby stopping the transmission of pain signals along the nerve fibers in the treated area.

The appropriate dose of Lignocainum Jelfa is determined by the prescribing healthcare professional based on the specific procedure, patient characteristics, and clinical guidelines. The prescriber will calculate the volume required to achieve effective urethral anesthesia while staying within safety limits.

Safety data for lidocaine use in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers should evaluate each case individually and discuss potential risks with the patient.

To order Lignocainum Jelfa, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and assist with import documentation.

Lignocainum Jelfa contains lidocaine, an amide‑type local anesthetic known for rapid onset and moderate duration of action. Compared with ester‑type agents such as procaine, lidocaine generally offers a faster onset, longer duration, and lower risk of allergic reactions, making it a preferred choice for urethral procedures.

Lignocainum Jelfa should be stored at ambient temperature, protected from direct light and moisture. Keep the product in its original sealed container until use, and avoid exposing it to extreme temperatures or humidity to maintain sterility and potency.

The solution is applied directly to the urethral mucosa by a qualified healthcare professional. It is typically instilled using a sterile catheter or syringe, allowing the drug to coat the target area before the procedure begins. Administration is performed in a controlled clinical setting.

The most serious risks include systemic toxicity leading to central nervous system effects such as seizures, cardiac arrhythmias, severe allergic reactions (anaphylaxis), and rare cases of methemoglobinemia. Prompt recognition of symptoms and immediate medical intervention are essential if these events occur.

Patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid using Lignocainum Jelfa. Additionally, individuals with severe cardiac conduction disorders, uncontrolled epilepsy, or those taking medications that significantly raise lidocaine levels should be evaluated carefully before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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