Product image of Lignox (Lidocaine Hydrochloride) supplied by GNH India

Lignox

Active Ingredient:
Lidocaine Hydrochloride
Origin:
EU

Lignox (Lidocaine Hydrochloride)

Lidocaine Hydrochloride, the active ingredient in Lignox, is a local anesthetic presented as a formulation for oromucosal use. It provides temporary loss of sensation in the oral mucosa for dental procedures, minor surgeries, and relief of oral pain.
GNH India supplies Lignox as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Chema Elektromet Spoldzielnia Pracy

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Indications & Clinical Uses

Lignox, a lidocaine‑based local anesthetic, is applied to the oral mucosa to achieve temporary numbness and pain control.

  • Oral mucosal anesthesia: provides localized loss of sensation for dental extractions, scaling, and minor oral surgeries.
  • Treatment of aphthous ulcers: reduces pain and facilitates healing of mouth sores.
  • Sore throat relief: numbs the oropharyngeal mucosa to alleviate discomfort from inflammation or irritation.

How It Works

  • Lidocaine Hydrochloride blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of action potentials. By inhibiting sodium influx, it halts nerve impulse conduction in the targeted area, resulting in reversible loss of sensation and analgesia at the site of application.

Side Effects

Lignox may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Burning or tingling at the application site
  • Mild oral irritation or erythema
  • Taste alteration or metallic taste
  • Nausea or mild gastrointestinal upset
  • Headache

Serious or Rare Side Effects

  • Allergic reaction (rash, pruritus, angioedema)
  • Systemic toxicity (dizziness, seizures, cardiac arrhythmia)
  • Methemoglobinemia (rare, cyanosis)
  • Persistent numbness beyond expected duration

Precautions & Warnings

When using Lignox, consider the following safety measures.

  • Patient assessment: evaluate for known lidocaine allergy or hypersensitivity before application.
  • Dosage control: avoid exceeding the recommended amount to reduce risk of systemic absorption.
  • Concurrent anesthetics: limit use with other local anesthetics to prevent cumulative toxicity.
  • Medical conditions: use cautiously in patients with cardiac conduction disorders or severe hepatic impairment.
  • Pregnancy and lactation: assess risk‑benefit ratio as safety data are limited.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Lignox can interact with other substances that affect cardiac conduction or increase systemic lidocaine levels.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may potentiate cardiac toxicity.
  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): can increase lidocaine plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Other local anesthetics: cumulative effect may raise toxicity risk.
  • Beta‑blockers: may enhance lidocaine’s depressant effect on cardiac conduction.
  • Diuretics (e.g., furosemide): may alter lidocaine clearance, requiring monitoring.

Frequently Asked Questions

Lignox contains lidocaine hydrochloride and is used to provide temporary local anesthesia of the oral mucosa. It is applied before dental procedures, minor oral surgeries, and to relieve pain from mouth ulcers or sore throat.

Lidocaine blocks voltage‑gated sodium channels on nerve cells, preventing the influx of sodium ions required for action potential generation. This interruption stops nerve impulse transmission, producing reversible numbness in the area where the product is applied.

The appropriate dose of Lignox is determined by the prescribing clinician based on the procedure, patient age, weight, and overall health. Healthcare professionals calculate the amount needed to achieve effective local anesthesia while minimizing systemic exposure.

Safety data for lidocaine hydrochloride in pregnancy and lactation are limited. Clinicians should weigh the potential benefits against any possible risks and consider alternative treatments when appropriate. Consultation with a obstetrician or pediatrician is recommended.

To order Lignox, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Lignox (lidocaine) is a widely used amide‑type local anesthetic offering rapid onset and moderate duration of action. Compared with benzocaine, lidocaine provides deeper tissue penetration and a more predictable safety profile, while agents like benzocaine may have a higher risk of methemoglobinemia.

Lignox should be stored below 25 °C in its original container, protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposure to extreme temperatures that could compromise its stability.

Lignox is applied directly to the oral mucosa using the supplied applicator or swab. The clinician spreads a thin layer over the target area, allowing the medication to absorb and produce local anesthesia within minutes.

Serious risks include allergic reactions such as rash, angioedema, or anaphylaxis, and systemic lidocaine toxicity, which can manifest as dizziness, seizures, or cardiac arrhythmias. Immediate medical attention is required if any of these symptoms occur.

Individuals with a known hypersensitivity to lidocaine or other amide‑type local anesthetics should avoid Lignox. Patients with severe cardiac conduction disorders, significant hepatic impairment, or those taking interacting medications listed under major interactions should also be evaluated carefully before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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