Product image of Lilia (Chlormadinone Acetate, Ethinylestradiol) supplied by GNH India

Lilia

Active Ingredient:
Chlormadinone Acetate, Ethinylestradiol
Origin:
EU

Lilia (Chlormadinone Acetate, Ethinylestradiol)

Chlormadinone acetate and ethinylestradiol, the active ingredients in Lilia, are a combined oral contraceptive presented as a tablet for oral use. It prevents pregnancy in women of reproductive age by inhibiting ovulation and creating cervical mucus changes.
GNH India supplies Lilia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aristo Pharma Gmbh (Art 57)

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Indications & Clinical Uses

Lilia is a combined hormonal contraceptive that acts on the hypothalamic‑pituitary‑ovarian axis to prevent pregnancy.

  • Pregnancy prevention: provides reliable birth control for women of childbearing potential.
  • Oral contraception: offers a daily oral regimen to inhibit ovulation and fertilisation.
  • Menstrual cycle regulation: helps achieve more predictable menstrual bleeding patterns.

How It Works

  • Lilia combines an estrogen (ethinylestradiol) and a progestogen (chlormadinone acetate). Ethinylestradiol stabilises the endometrial lining, while chlormadinone acetate suppresses the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH), thereby inhibiting ovulation. The formulation also thickens cervical mucus and alters the endometrium, reducing the likelihood of fertilisation and implantation.

Side Effects

Lilia may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or migraine‑like pain.
  • Breast tenderness: discomfort or swelling of the breasts.
  • Irregular bleeding: spotting or breakthrough bleeding between periods.

Serious or Rare Side Effects

  • Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism.
  • Hypertension: new‑onset or worsening high blood pressure.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.

Precautions & Warnings

Before prescribing Lilia, clinicians should evaluate individual risk factors and counsel patients on safety considerations.

  • Contraindicated in pregnancy: product is classified as pregnancy category X and must not be used.
  • Avoid in smokers over 35 years: increased risk of cardiovascular events.
  • Assess history of thromboembolic disorders: risk of clot formation may be elevated.
  • Monitor blood pressure regularly: may cause or worsen hypertension.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Lilia can interact with several medicines that affect hormone metabolism or increase clotting risk.

Major Interactions (Avoid)

  • Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): may reduce contraceptive efficacy.
  • Strong CYP3A4 inducers (e.g., rifampicin, griseofulvin): can lower hormone levels.
  • Other estrogen‑containing products (e.g., hormone replacement therapy): may increase estrogen exposure.

Moderate Interactions (Monitor Closely)

  • Certain antibiotics (e.g., metronidazole): may slightly diminish effectiveness.
  • Antifungals such as ketoconazole: can increase hormone concentrations.
  • St. John’s wort herbal supplement: may decrease contraceptive reliability.

Frequently Asked Questions

Lilia is a combined oral contraceptive containing chlormadinone acetate and ethinylestradiol. It is prescribed to prevent pregnancy in women of reproductive age and can also be used to regulate menstrual bleeding patterns as part of family‑planning therapy.

The ethinylestradiol component provides estrogenic activity that stabilises the endometrial lining, while chlormadinone acetate acts as a progestogen. Together they suppress the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH), inhibiting ovulation and inducing cervical mucus changes that impede sperm penetration.

The specific dosing regimen for Lilia is determined by the prescribing clinician based on the product’s labeling and the patient’s individual needs. Typically, combined oral contraceptives are taken once daily for 21 days followed by a hormone‑free interval, but the exact schedule should be confirmed with a qualified health‑care professional.

Lilia is classified as pregnancy category X, meaning it must not be used during pregnancy because it can cause fetal harm. It is also not recommended for breastfeeding women, as hormonal contraceptives may affect milk production and expose the infant to estrogen and progestogen. Alternative non‑hormonal methods should be considered in these situations.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Lilia. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any required temperature control) and necessary import documentation.

Lilia contains chlormadinone acetate as the progestogenic component, which is less commonly used than levonorgestrel or desogestrel in many other pills. This may offer a different side‑effect profile, such as lower androgenic activity, but overall efficacy in preventing pregnancy is comparable to other FDA‑approved combined oral contraceptives when taken correctly.

Lilia tablets should be stored at ambient temperature, below 25 °C (77 °F). Keep them in the original blister pack or container, protect from moisture, heat and direct sunlight, and ensure they are out of reach of children. Do not store in the bathroom or near a kitchen sink where humidity is high.

Lilia is taken orally, usually as a tablet taken at the same time each day. The typical regimen involves a 21‑day active tablet sequence followed by a 7‑day pill‑free interval, during which withdrawal bleeding occurs. Patients should swallow the tablet whole with water and should not split or crush it.

The most serious risks include venous thromboembolism (deep‑vein thrombosis or pulmonary embolism), arterial thrombosis leading to stroke or myocardial infarction, and severe hypertension. Women with a history of clotting disorders, smoking over age 35, or certain cardiovascular conditions should avoid Lilia and seek alternative contraception.

Lilia is contraindicated in women who are pregnant or suspect they may be pregnant, those with known or suspected estrogen‑dependent tumors, active or history of thromboembolic disease, uncontrolled hypertension, severe liver disease, or who are smokers aged 35 years or older. It should also be avoided in individuals with known hypersensitivity to either chlormadinone acetate or ethinylestradiol.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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