Product image of Limetic (Desogestrel) supplied by GNH India

Limetic

Active Ingredient:
Desogestrel
Origin:
EU

Limetic (Desogestrel)

Desogestrel, the active ingredient in Limetic, is a progestin presented as an oral tablet for oral use. It is employed to prevent pregnancy in women of reproductive age by inhibiting ovulation and modifying cervical mucus. The tablet is formulated to deliver a consistent dose of desogestrel, ensuring reliable contraceptive efficacy when taken at the same time each day.

GNH India supplies Limetic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance.

Manufacturer / TM Owner

Zaklady Farmaceutyczne Polpharma S.A.

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Indications & Clinical Uses

Desogestrel is a progestin‑only hormonal agent used in contraception and related menstrual management.

  • Contraception (progestin‑only pill): prevents ovulation and pregnancy in women of child‑bearing age.
  • Hormonal birth control alternative: serves as a single‑component option for women who cannot use estrogen‑containing pills.
  • Menstrual cycle management: can help stabilize menstrual bleeding in some users.

How It Works

  • Desogestrel exerts its contraceptive effect by binding to the progesterone receptor in the hypothalamus and pituitary, suppressing the luteinizing hormone surge required for ovulation. It also induces changes in the cervical mucus, making it thicker and less permeable to sperm, and alters the endometrial lining to reduce the likelihood of implantation. These combined actions maintain a high level of contraceptive reliability throughout the dosing cycle.

Side Effects

Desogestrel may be associated with a range of adverse reactions, varying in frequency and severity.

Common Side Effects

  • Irregular vaginal bleeding or spotting
  • Headache
  • Nausea
  • Breast tenderness

Serious or Rare Side Effects

  • Deep vein thrombosis or pulmonary embolism
  • Severe allergic reaction (anaphylaxis)
  • Liver dysfunction (jaundice, hepatitis)

Precautions & Warnings

When prescribing Limetic, clinicians should consider several safety aspects.

  • Assess contraindications: history of thromboembolic disorders, hormone‑sensitive cancers, or severe liver disease.
  • Monitor blood pressure: progestins may cause hypertension in susceptible individuals.
  • Evaluate smoking status: increased cardiovascular risk in women over 35 who smoke.
  • Consider drug interactions: enzyme‑inducing agents can lower contraceptive efficacy.
  • Counsel on missed doses: follow specific guidance to maintain protection.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light.

Avoid Interactions

Desogestrel can interact with other medicines, affecting its contraceptive reliability.

Major Interactions (Avoid)

  • Rifampin and other strong enzyme inducers: may significantly reduce desogestrel plasma levels, compromising contraceptive effect.
  • Antiepileptic drugs such as phenytoin, carbamazepine, phenobarbital: can decrease hormone effectiveness.
  • St. John’s wort: herbal inducer that may lower contraceptive reliability.

Moderate Interactions (Monitor Closely)

  • Azole antifungals (ketoconazole, itraconazole): may increase hormone concentrations, raising risk of side effects.
  • Antiretroviral efavirenz: may modestly reduce desogestrel efficacy.
  • Certain antibiotics (e.g., tetracycline, metronidazole): may have a slight impact on contraceptive reliability.

Frequently Asked Questions

Limetic contains desogestrel, a progestin indicated for hormonal contraception. It is prescribed to prevent pregnancy in women of reproductive age when taken as a daily oral tablet. It works as a progestin‑only pill, offering an alternative to combined oral contraceptives.

Desogestrel binds to progesterone receptors in the hypothalamus and pituitary, suppressing the luteinizing hormone surge that triggers ovulation. It also thickens cervical mucus, making it hostile to sperm, and modifies the endometrial lining, reducing the chance of implantation. These actions together provide reliable contraceptive protection.

The specific dosage regimen for Limetic is determined by the prescribing healthcare professional based on the product’s labeling and the patient’s individual needs. Typically, desogestrel‑containing progestin‑only pills are taken once daily at the same time, but the exact dose and schedule should be confirmed by the prescriber.

Limetic is intended for use as a contraceptive and should not be started during pregnancy. If pregnancy occurs, the product should be discontinued. Limited data are available on use while breastfeeding; healthcare providers usually assess the risk‑benefit ratio before prescribing to nursing mothers.

To place an order, submit an enquiry on the Limetic product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with combined oral contraceptives that contain estrogen and progestin, Limetic provides a progestin‑only option, which may be preferable for women who cannot tolerate estrogen. Its efficacy is similar when taken correctly, and it avoids estrogen‑related side effects such as increased clotting risk, though it shares many progestin‑related adverse effects.

Limetic tablets should be stored at ambient temperature, below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged or the tablets appear discolored.

Limetic is taken orally, usually as a single tablet each day at the same time, without regard to meals. Consistent daily intake is important to maintain contraceptive effectiveness. If a dose is missed, follow the product’s missed‑dose instructions or consult a healthcare professional.

The most serious risks include thromboembolic events such as deep‑vein thrombosis or pulmonary embolism, severe allergic reactions (anaphylaxis), and liver dysfunction. Women with a history of clotting disorders, hormone‑sensitive cancers, or severe liver disease should discuss these risks with their prescriber before using Limetic.

Limetic is contraindicated in women with known or suspected pregnancy, active thromboembolic disease, severe liver impairment, hormone‑dependent tumors, or those who are breastfeeding and wish to avoid medication exposure. Additionally, women who are smokers over 35 years of age should consider alternative contraceptive methods due to increased cardiovascular risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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