Product image of Limpidex (Lansoprazole) supplied by GNH India

Limpidex

Active Ingredient:
Lansoprazole
Origin:
EU

Limpidex (Lansoprazole)

Lansoprazole, the active ingredient in Limpidex, is a proton pump inhibitor presented as an oral tablet for oral use. It reduces gastric acid production and is used to treat conditions such as gastro‑oesophageal reflux disease, peptic ulcers and Zollinger‑Ellison syndrome in adult patients.

GNH India supplies Limpidex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Alfasigma S.P.A.

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Indications & Clinical Uses

Lansoprazole acts on the gastric acid secretion pathway and is indicated for several acid‑related disorders.

  • Gastro‑oesophageal reflux disease (GERD): provides symptomatic relief and promotes healing of esophageal irritation.
  • Duodenal ulcer: promotes ulcer healing by suppressing gastric acid.
  • Gastric ulcer: aids in ulcer resolution through acid reduction.
  • Helicobacter pylori eradication (in combination therapy): enhances eradication rates when used with antibiotics.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid secretion in this rare condition.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid production, it markedly reduces both basal and stimulated gastric acid secretion, leading to an increase in gastric pH and facilitating ulcer healing and symptom control.

Side Effects

Lansoprazole is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: usually self‑limiting.
  • Nausea: occasional, may improve with food.
  • Abdominal pain: mild discomfort.
  • Flatulence: increased gas.
  • Constipation: occasional.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: persistent watery diarrhea.
  • Low magnesium levels: muscle cramps, irregular heartbeat.
  • Bone fracture risk: long‑term use may affect bone density.
  • Liver enzyme elevation: abnormal liver function tests.
  • Acute interstitial nephritis: kidney inflammation.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess renal function: adjust use in severe impairment.
  • Evaluate hepatic status: use caution in liver disease.
  • Review concomitant medications: potential for drug‑drug interactions.
  • Monitor for infection: prolonged acid suppression may increase risk of gastrointestinal infections.
  • Pregnancy and lactation: discuss risks with a healthcare professional.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Avoid Interactions

Lansoprazole may alter the pharmacokinetics of several co‑administered drugs.

Major Interactions (Avoid)

  • Ketoconazole or itraconazole: reduced antifungal absorption.
  • Atazanavir: decreased antiviral efficacy.
  • Clopidogrel: diminished antiplatelet effect.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, monitor coagulation.
  • Methotrexate: higher serum levels, watch for toxicity.
  • Digoxin: altered plasma concentration, adjust dose if needed.

Frequently Asked Questions

Limpidex, containing lansoprazole, is prescribed for acid‑related disorders such as gastro‑oesophageal reflux disease, duodenal and gastric ulcers, Helicobacter pylori eradication regimens (in combination with antibiotics), and Zollinger‑Ellison syndrome, where excessive gastric acid production is a primary concern.

Lansoprazole blocks the H+/K+ ATPase enzyme, also known as the gastric proton pump, on the surface of parietal cells. By irreversibly inhibiting this pump, it stops the final step of acid secretion, leading to a sustained increase in gastric pH and reduction of acid‑related damage.

The dosage of Limpidex is determined by the prescribing clinician based on the specific indication, patient age, renal and hepatic function, and treatment response. Patients should follow the dose and schedule provided by their healthcare professional.

Safety data for lansoprazole in pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits against any possible risks before prescribing Limpidex to pregnant or nursing individuals.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Limpidex (lansoprazole) belongs to the proton pump inhibitor class, offering more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, its efficacy is similar, though individual response and drug‑interaction profiles may differ.

Limpidex should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed until use.

Limpidex is taken orally, usually as a whole tablet with a glass of water. It is generally recommended to swallow the tablet before a meal, unless the prescribing clinician advises otherwise.

Serious adverse events, though rare, include severe allergic reactions, Clostridioides difficile‑associated diarrhea, low magnesium levels, increased risk of bone fractures with long‑term use, and liver enzyme abnormalities. Patients should seek medical attention if they experience any of these symptoms.

Limpidex is contraindicated in individuals with known hypersensitivity to lansoprazole or any component of the formulation. Caution is advised for patients with severe liver disease, and it should be avoided in those taking medications that have major interactions unless closely monitored.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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