Product image of Linagliptin Eg (Linagliptin) supplied by GNH India

Linagliptin Eg

Active Ingredient:
Linagliptin
Origin:
EU

Linagliptin Eg (Linagliptin)

Linagliptin, the active ingredient in Linagliptin Eg, is a dipeptidyl peptidase-4 (DPP-4) inhibitor presented as an oral tablet for oral use. It treats type 2 diabetes mellitus in adult patients by improving glucose‑dependent insulin secretion.
GNH India supplies Linagliptin Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eg S.P.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Linagliptin is a DPP‑4 inhibitor used in the management of disorders related to impaired glucose regulation, primarily type 2 diabetes mellitus.
  • Type 2 diabetes mellitus: improves glycemic control by enhancing insulin secretion and reducing glucagon release in a glucose‑dependent manner.
  • Adjunctive therapy with metformin or other oral agents: provides additional HbA1c reduction when monotherapy does not achieve target levels.

How It Works

  • Linagliptin selectively inhibits the enzyme dipeptidyl peptidase‑4 (DPP‑4), preventing the breakdown of the incretin hormones GLP‑1 and GIP. Elevated incretin levels enhance glucose‑dependent insulin secretion, suppress glucagon release, and slow gastric emptying, resulting in lower post‑prandial and fasting blood glucose concentrations.

Side Effects

Common Side Effects

  • Nasopharyngitis: mild inflammation of the nose and throat.
  • Headache: transient head pain.
  • Gastrointestinal discomfort: mild nausea or abdominal pain.

Serious or Rare Side Effects

  • Pancreatitis: inflammation of the pancreas that may be severe.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Hepatic enzyme elevation: abnormal liver function tests.

Precautions & Warnings

Linagliptin should be used with clinical vigilance in several situations.

  • Renal impairment: assess kidney function before initiating therapy.
  • Hepatic impairment: monitor liver enzymes periodically.
  • Hypersensitivity: discontinue immediately if an allergic reaction occurs.
  • Pregnancy and lactation: prescribe only if potential benefits outweigh risks.
  • Concomitant antidiabetic agents: adjust doses to avoid hypoglycaemia.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Linagliptin may interact with several drug classes.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors: may increase linagliptin exposure.
  • Strong CYP3A4 inducers: may reduce linagliptin efficacy.

Moderate Interactions (Monitor Closely)

  • Diuretics: may affect blood‑glucose control.
  • Insulin or sulfonylureas: increased risk of hypoglycaemia.
  • Rifampin: may lower plasma concentrations of linagliptin.

Frequently Asked Questions

Linagliptin Eg is used to improve blood‑glucose control in adults with type 2 diabetes mellitus, usually as part of a comprehensive treatment plan that includes diet, exercise, and possibly other antidiabetic medicines.

Linagliptin works by selectively inhibiting the enzyme dipeptidyl peptidase‑4 (DPP‑4). This inhibition raises levels of the incretin hormones GLP‑1 and GIP, which enhance insulin secretion and suppress glucagon release in a glucose‑dependent manner, thereby lowering blood glucose.

The specific dose of Linagliptin Eg is determined by the prescribing healthcare professional based on the patient’s clinical condition, renal function, and concomitant therapies. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

The safety of linagliptin in pregnancy and lactation has not been established. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Linagliptin shares the same mechanism of action as other DPP‑4 inhibitors but has a distinct pharmacokinetic profile, allowing once‑daily dosing without dose adjustment in mild to moderate renal impairment, which can be an advantage over some alternatives.

Linagliptin Eg should be stored at ambient temperature below 25 °C, in the original packaging, protected from moisture and direct sunlight. Keep the container tightly closed and out of reach of children.

Linagliptin Eg is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water and not chewed or crushed.

Serious risks include pancreatitis, severe allergic reactions such as anaphylaxis, and significant elevations in liver enzymes. Patients should seek immediate medical attention if they experience persistent abdominal pain, rash, swelling, or signs of liver dysfunction.

Linagliptin Eg is contraindicated in patients with a known hypersensitivity to linagliptin or any of the tablet’s excipients. It should also be avoided in individuals with a history of severe pancreatitis until the cause is clarified.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.