Product image of Linagliptina Mylan (Linagliptin) supplied by GNH India

Linagliptina Mylan

Active Ingredient:
Linagliptin
Origin:
EU

Linagliptina Mylan (Linagliptin)

Linagliptin, the active ingredient in Linagliptina Mylan, is a dipeptidyl peptidase‑4 (DPP‑4) inhibitor presented as a tablet for oral use. It is indicated for the management of type 2 diabetes mellitus in adult patients, helping to improve glycemic control when used as part of a comprehensive treatment plan.

GNH India supplies Linagliptina Mylan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable access to quality‑assured medicines.

Manufacturer / TM Owner

Viatris Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Linagliptin is used to treat disorders of glucose metabolism, primarily type 2 diabetes mellitus.

  • Type 2 diabetes mellitus (monotherapy): reduces fasting and post‑prandial glucose levels as a single agent.
  • Type 2 diabetes mellitus (combination therapy): enhances glycemic control when added to metformin, sulfonylureas, or insulin.
  • Type 2 diabetes mellitus (adjunct to diet and exercise): supports overall blood glucose management as part of lifestyle interventions.

How It Works

  • Linagliptin reversibly binds to the active site of dipeptidyl peptidase‑4 (DPP‑4), inhibiting its enzymatic activity. This prevents the degradation of the incretin hormones GLP‑1 and GIP, leading to higher circulating levels of these hormones. The increased incretin effect enhances glucose‑dependent insulin secretion and suppresses glucagon release, thereby lowering blood glucose concentrations in patients with type 2 diabetes.

Side Effects

Common Side Effects

  • Upper respiratory tract infection: mild symptoms such as cough or sore throat.
  • Nasopharyngitis: inflammation of the nasal passages and throat.
  • Headache: transient mild to moderate pain.
  • Gastrointestinal discomfort: occasional nausea or abdominal pain.
  • Skin rash: mild erythematous eruptions.

Serious or Rare Side Effects

  • Pancreatitis: severe abdominal pain with vomiting, requiring immediate medical attention.
  • Severe hypersensitivity reactions: including angioedema or anaphylaxis.
  • Hepatic injury: elevated liver enzymes or jaundice.
  • Acute kidney injury: sudden decline in renal function, especially in patients with pre‑existing kidney disease.

Precautions & Warnings

Linagliptina Mylan should be used under medical supervision with regular monitoring of glycemic control.

  • Renal impairment: dose adjustment is not required, but monitor kidney function regularly.
  • Hepatic disease: use with caution; assess liver enzymes periodically.
  • Cardiovascular risk: evaluate cardiovascular status, especially in patients with established disease.
  • Concomitant antidiabetic agents: adjust therapy to avoid hypoglycemia.
  • Pregnancy and lactation: safety not established; avoid unless benefits outweigh risks.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Linagliptina Mylan may interact with several drug classes; careful review of the patient's medication list is essential.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): may increase linagliptin exposure.
  • Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce linagliptin efficacy.

Moderate Interactions (Monitor Closely)

  • Insulin or insulin secretagogues (e.g., sulfonylureas): increased risk of hypoglycemia; adjust dose as needed.
  • Diuretics and antihypertensives: monitor blood pressure and electrolytes.
  • Anticoagulants (e.g., warfarin): periodic INR checks are advisable.

Frequently Asked Questions

Linagliptina Mylan contains the active ingredient linagliptin, a DPP‑4 inhibitor indicated for the treatment of type 2 diabetes mellitus in adult patients. It helps lower blood glucose levels when used as part of a comprehensive diabetes management plan that includes diet, exercise, and other antidiabetic agents as prescribed.

Linagliptin works by reversibly inhibiting the enzyme dipeptidyl peptidase‑4 (DPP‑4). This inhibition prevents the breakdown of the incretin hormones GLP‑1 and GIP, which increases their levels in the bloodstream. Higher incretin levels enhance glucose‑dependent insulin secretion and suppress glucagon release, resulting in improved glycemic control.

The specific dose of Linagliptina Mylan is determined by the prescribing healthcare professional based on the individual’s clinical condition, renal and hepatic function, and concomitant therapies. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

The safety of linagliptin in pregnancy and lactation has not been established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss alternative treatment options with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and assist with import documentation.

Linagliptin is unique among DPP‑4 inhibitors because it is primarily eliminated via the entero‑hepatic route and does not require dose adjustment in renal impairment, unlike many of its peers. Efficacy in lowering HbA1c is comparable to other agents in the class, while its safety profile is similar, with low risk of hypoglycemia when used as monotherapy.

Linagliptina Mylan should be stored at ambient temperature, below 25 °C (77 °F). Keep the tablets in the original blister pack or container, protect them from moisture, heat, and direct sunlight. Do not store in the bathroom or near a kitchen sink. Ensure the product is kept out of reach of children.

Linagliptina Mylan is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the dosing schedule prescribed by their healthcare professional and should not split, crush, or chew the tablet unless specifically instructed.

The most serious risks include pancreatitis, severe hypersensitivity reactions such as anaphylaxis or angioedema, and rare cases of hepatic injury. Patients should be educated to seek immediate medical attention if they experience persistent abdominal pain, signs of an allergic reaction, or unexplained jaundice while on therapy.

Linagliptina Mylan is contraindicated in patients with a known hypersensitivity to linagliptin or any of the tablet’s excipients. It should be used with caution in individuals with a history of pancreatitis, severe hepatic impairment, or uncontrolled heart failure. Pregnant or breastfeeding women should only use it if clearly indicated by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.