Product image of Linatilsan (Enalapril Maleate) supplied by GNH India

Linatilsan

Active Ingredient:
Enalapril Maleate
Origin:
EU

Linatilsan (Enalapril Maleate)

Enalapril, the active ingredient in Linatilsan, is an ACE inhibitor presented as an oral tablet for oral use. It is prescribed to manage hypertension and several forms of heart failure, reducing cardiovascular strain in adult patients. By inhibiting the conversion of angiotensin I to angiotensin II, the drug promotes vasodilation and lowers blood pressure.

GNH India supplies Linatilsan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams worldwide. The company adheres to stringent quality standards and provides regulatory documentation for export.

Manufacturer / TM Owner

Sandoz Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Enalapril is used in cardiovascular conditions that involve the renin‑angiotensin system.
  • Hypertension: lowers blood pressure and reduces the risk of stroke and heart attack.
  • Heart failure: improves symptoms and decreases mortality in patients with reduced ejection fraction.
  • Asymptomatic left ventricular dysfunction: delays progression to symptomatic heart failure.
  • Post‑myocardial infarction: reduces the likelihood of subsequent cardiovascular events.

How It Works

  • Enalapril is a prodrug that is hydrolyzed to enalaprilat, a potent inhibitor of angiotensin‑converting enzyme (ACE). By blocking ACE, it prevents the conversion of angiotensin I to the vasoconstrictor angiotensin II and reduces degradation of bradykinin. The resulting vasodilation, decreased aldosterone secretion, and lowered sodium‑water retention collectively lower systemic vascular resistance and arterial pressure. These actions help to improve cardiac output and reduce the workload on the heart.

Side Effects

Enalapril may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Cough: persistent dry cough.
  • Dizziness: light‑headedness, especially after standing.
  • Headache: mild to moderate headache.
  • Fatigue: general tiredness.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips, tongue or throat.
  • Hyperkalemia: elevated blood potassium levels.
  • Neutropenia: reduced white blood cell count.
  • Hepatic dysfunction: abnormal liver enzymes or hepatitis.

Precautions & Warnings

When prescribing Enalapril, clinicians should consider several safety precautions to minimize risks.

  • Blood pressure monitoring: check for hypotension after initiation or dose changes.
  • Renal function assessment: evaluate serum creatinine and eGFR before and during therapy.
  • Electrolyte surveillance: monitor potassium levels to detect hyperkalemia.
  • Pregnancy and lactation: use only if clearly needed and after consulting a specialist.
  • Store at ambient temperature: keep below 25 °C in the original container, protect from moisture and light.

Avoid Interactions

Enalapril can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Aliskiren: combined use may increase risk of renal impairment and hyperkalemia.
  • Potassium‑sparing diuretics or supplements: may cause dangerous hyperkalemia.
  • NSAIDs (e.g., ibuprofen, naproxen): can reduce antihypertensive effect and impair renal function.

Moderate Interactions (Monitor Closely)

  • Lithium: ACE inhibition may raise lithium levels, requiring dose adjustment.
  • Diuretics (loop or thiazide): may enhance hypotensive effect; monitor blood pressure.

Frequently Asked Questions

Linatilsan contains enalapril, an ACE inhibitor that is used to treat high blood pressure, chronic heart failure, asymptomatic left ventricular dysfunction, and to reduce cardiovascular risk after a myocardial infarction. It works by relaxing blood vessels and decreasing the heart's workload.

Enalapril is converted in the body to enalaprilat, which blocks the angiotensin‑converting enzyme (ACE). This inhibition prevents the formation of angiotensin II, a potent vasoconstrictor, and reduces aldosterone release, leading to vasodilation, lower blood pressure, and decreased fluid retention.

The appropriate dose of Linatilsan is determined by a qualified healthcare professional based on the individual’s medical condition, response to therapy, and other factors. Patients should follow the prescribing physician’s instructions and not adjust the dose on their own.

Safety of enalapril during pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a healthcare provider.

To order Linatilsan, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Linatilsan (enalapril) is comparable to other ACE inhibitors such as lisinopril or ramipril in efficacy for blood‑pressure control and heart‑failure management. Unlike ARBs, which block angiotensin II receptors, ACE inhibitors also increase bradykinin levels, which can lead to a characteristic dry cough in some patients.

Linatilsan tablets should be stored at ambient temperature, preferably below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged.

Linatilsan is taken orally, usually with or without food, as directed by a physician. The tablet should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed by a healthcare professional.

Serious adverse reactions include angioedema (swelling of the face, lips, tongue or throat), severe hypotension, hyperkalemia (high potassium levels), and renal impairment. Patients should seek immediate medical attention if they experience swelling, difficulty breathing, sudden dizziness, or a rapid rise in blood potassium.

Linatilsan should be avoided in individuals with a known hypersensitivity to enalapril or any ACE inhibitor, those with a history of angioedema related to ACE‑inhibitor therapy, and patients with severe renal artery stenosis. Caution is also advised for patients with advanced kidney disease or high potassium levels.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.